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4-Chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine

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Identification
Molecular formula
C16H15ClN2
CAS number
82076-99-5
IUPAC name
4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine
State
State

At room temperature, this compound is a solid. Its crystalline nature allows it to maintain structural integrity under standard laboratory conditions.

Melting point (Celsius)
252.00
Melting point (Kelvin)
525.15
Boiling point (Celsius)
560.00
Boiling point (Kelvin)
833.15
General information
Molecular weight
236.76g/mol
Molar mass
236.7100g/mol
Density
1.2600g/cm3
Appearence

The compound typically appears as a crystalline solid. Usually, it is characterized by its off-white to light yellow color, depending on the degree of purity and presence of impurities. The crystalline form makes it more stable and easier to handle in comparison to other forms.

Comment on solubility

Solubility of 4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine

The solubility characteristics of 4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine can be intricate due to its unique molecular structure. This compound, belonging to the class of nitrogen-containing heterocycles, generally demonstrates the following solubility behavior:

  • Polar Solvents: It tends to be more soluble in polar solvents such as water or methanol. The presence of amine groups can facilitate hydrogen bonding, enhancing solubility in these environments.
  • Non-Polar Solvents: Conversely, its solubility is limited in non-polar organic solvents due to the hydrophobic nature of the cycloheptane ring.
  • Temperature Dependence: Like many organic compounds, the solubility may increase with temperature, allowing for better dissolution in solvents at elevated temperatures.
  • pH Sensitivity: The solubility can be affected by pH levels; under acidic conditions, protonation of the amine group could increase solubility, while in basic conditions, it may lead to precipitation depending on its ionic nature.

In summary, the solubility of 4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine is influenced by several factors including solvent polarity, temperature, and pH. As with many compounds of this class, understanding these interactions is crucial for employing the right solubility conditions in practical applications.

Interesting facts

Interesting Facts about 4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine

This intriguing chemical compound is notable for several reasons, mainly due to its structural complexity and potential biological applications. Here are some interesting facts:

  • Cyclic Structure: It features a unique bicyclic structure, which is common in various natural products and pharmaceuticals. The presence of multiple fused rings contributes to its interesting chemical properties.
  • Chlorine Substitution: The chlorine atom in this compound plays a critical role. Chlorinated compounds often exhibit enhanced biological activity and can act as key intermediates in organic synthesis.
  • Potential Applications: Compounds with a similar structure have been researched for their potential applications in medicinal chemistry, particularly as antitumor and antiviral agents. This raises questions about its interaction with biological systems.
  • Synthesis Challenges: Synthesizing such complex molecules can pose challenges, notably regarding reaction conditions and purification techniques. Understanding these processes can be crucial for developing efficient synthetic routes.
  • Research Interest: Scientists are continually exploring the pharmacological properties of compounds like this one. Research may include mechanistic studies to understand how it interacts with biological targets.
  • Environmental Considerations: As with many chlorinated compounds, it’s important to consider the environmental impact of synthesis and degradation products, prompting a balanced approach toward its utilization.

In summary, 4-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine is not just a chemical formula; it is a potential gateway to discovering new therapeutic agents and understanding the intricacies of chemical reactions involving complex organic structures.

Synonyms
MAS 805
BRN 0401342
5778-90-5
6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-4-CHLORO-
DTXSID30206472
7,8,9,10-Tetrahydro-11-amino-4-chloro-6H-cyclohepta(b)quinoline
DTXCID30128963
5-22-10-00501 (beilstein handbook reference)
AKOS012656488