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Tepoxalin

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Identification
Molecular formula
C20H20ClN3O2
CAS number
103475-41-8
IUPAC name
4-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-benzamide
State
State

At room temperature, Tepoxalin is typically a solid. It is primarily used in pharmaceutical preparations, often formulated into different dosages for veterinary medicine applications, particularly for dogs.

Melting point (Celsius)
243.00
Melting point (Kelvin)
516.15
Boiling point (Celsius)
462.20
Boiling point (Kelvin)
735.35
General information
Molecular weight
372.85g/mol
Molar mass
372.8400g/mol
Density
1.3000g/cm3
Appearence

Tepoxalin typically appears as a crystalline solid. It may vary in color from white to off-white depending on the specific formulation or impurities.

Comment on solubility

Solubility of 4-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-benzamide

The solubility of 4-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-benzamide is influenced by its structural characteristics and chemical interactions. Here are some key points regarding its solubility:

  • Polarity: This compound contains polar functional groups, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: The presence of amide groups can facilitate hydrogen bonding with solvents, particularly water, potentially increasing solubility.
  • Solubility in Organic Solvents: It is likely to be more soluble in organic solvents such as DMSO or ethanol compared to water.
  • Temperature Dependency: As with many organic compounds, solubility may increase with temperature, allowing for better dissolution in various solvents.

In summary, while the exact solubility characteristics of 4-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-benzamide can vary, its ability to engage in hydrogen bonding and its structural properties suggest that it may be soluble in a range of solvents under suitable conditions. Always consider conducting empirical solubility tests for precise determination.

Interesting facts

Interesting Facts about 4-Chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-benzamide

This compound, with its complex structure, represents a fascinating intersection of medicinal chemistry and organic synthesis. Its unique composition makes it a subject of interest among researchers focused on drug development and chemical interactions.

Potential Applications

Several notable applications and characteristics of this compound include:

  • Pharmacological Interest: The structure features a pyrazole ring, which is often found in many pharmaceuticals, suggesting potential medicinal properties.
  • Antimicrobial Activity: Compounds with similar structures have been studied for their effectiveness against a variety of pathogens, offering hope for new antimicrobial agents.
  • Inhibition Mechanisms: The presence of the chloro and benamide groups may enhance interactions with biological targets, providing insights into possible mechanisms of action.

Chemical Features

A closer look reveals:

  • Chlorine Substitution: The 4-chloro group can affect the compound's reactivity and interaction with enzymes, which is critical in pharmacology.
  • Keto Group: The 3-oxo functionality suggests a role in reactivity, potentially involving tautomerization and altered solubility in biological environments.
  • Dimethyl Substitution: The 1,5-dimethyl moiety may influence the structural stability and bioavailability of the compound, making it a vital consideration in drug formulation.

Research and Development

As scientists explore this compound, they often ask:

  • What is its mechanism of action at a molecular level?
  • How does it compare with other known compounds in terms of efficacy and safety?
  • Can derivatives of this compound yield more potent or specific therapeutic agents?

Overall, 4-chloro-N-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-N-ethyl-benzamide serves as a compelling example of how complex organic compounds can pave the way for advancements in medicinal chemistry and therapeutic research.

Synonyms
BENZAMIDE, N-ANTIPYRINYL-p-CHLORO-N-ETHYL-
15166-17-3
TA 6
BRN 0573152
N-Antipyrinyl-p-chloro-N-ethylbenzamide
DTXSID90164842