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Chloroethylphenoxamine

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Identification
Molecular formula
C19H28ClNO2
CAS number
77-38-0
IUPAC name
4-chloro-N-(2-hydroxyethyl)-N-[(3-methylnorbornan-2-yl)methyl]benzamide
State
State

At room temperature, chloroethylphenoxamine is typically in a crystalline solid state.

Melting point (Celsius)
70.00
Melting point (Kelvin)
343.15
Boiling point (Celsius)
365.00
Boiling point (Kelvin)
638.15
General information
Molecular weight
311.82g/mol
Molar mass
311.8240g/mol
Density
1.2004g/cm3
Appearence

Chloroethylphenoxamine typically appears as a white or off-white crystalline solid. It is often available in powdered form and may have a mild characteristic odor.

Comment on solubility

Solubility of 4-chloro-N-(2-hydroxyethyl)-N-[(3-methylnorbornan-2-yl)methyl]benzamide

The solubility of 4-chloro-N-(2-hydroxyethyl)-N-[(3-methylnorbornan-2-yl)methyl]benzamide can be quite complex due to its intricate molecular structure. Here are several factors that influence its solubility:

  • Polarity: The presence of the 2-hydroxyethyl group suggests a degree of polarity which may enhance water solubility to some extent.
  • Functional Groups: The amide bond typically allows for hydrogen bonding with water, which can also assist in solubility.
  • Molecular Size: The bulky structure introduced by the 3-methylnorbornan-2-yl substituent may hinder the overall solubility in polar solvents.
  • Solvent Dependency: It is likely to have variable solubility in different solvents – possibly being more soluble in organic solvents compared to water.

As a general observation, compounds of this nature often exhibit limited solubility in water while being more soluble in organic solvents due to the conflicting impacts of their polar and nonpolar regions. Hence, careful consideration should be given to the medium used for dissolution.

Interesting facts

Interesting Facts about 4-Chloro-N-(2-hydroxyethyl)-N-[(3-methylnorbornan-2-yl)methyl]benzamide

This compound is a fascinating member of the amide functional group that has garnered attention due to its diverse applications in various fields such as pharmaceuticals and material science. Let’s delve into some intriguing aspects of this interesting molecule:

  • Structural Diversity: The presence of both a chloro group and a hydroxyalkyl substituent makes this compound structurally unique, allowing it to interact with various biological systems effectively.
  • Potential Medical Applications: Compounds like this one are often evaluated for their potential as drug candidates. Their ability to modify biological pathways may be exploited in treating conditions such as cancer or neurodegenerative diseases.
  • Chiral Centers: This compound features chiral centers, which add complexity to its synthesis and potential interactions. Chirality plays a crucial role in pharmacodynamics, as different enantiomers can exhibit vastly different biological activities.
  • Interaction with Receptors: The hydroxyethyl group may enhance the solubility and biological availability of the compound, improving its interaction with specific receptors in the body.
  • Polymer Science: Due to its functional groups, it could serve as a precursor for polymers with tailored properties, demonstrating the versatility of amides in materials development.

In summary, 4-chloro-N-(2-hydroxyethyl)-N-[(3-methylnorbornan-2-yl)methyl]benzamide exemplifies the intricate relationship between structure and functionality in chemical compounds. As noted, “The chemist’s language is structure,” and this compound speaks volumes about the elegance of organic chemistry!

Synonyms
Clocanfamide
Chlorocamphamide
Clocanfamida
Clomiren
Clocanfamide [INN]
Clocanfamidum
Clocanfamidum [INN-Latin]
Clocanfamida [INN-Spanish]
UNII-21Q62BRI9U
BRN 2757291
21Q62BRI9U
p-Chloro-N-(2-hydroxyethyl)-N-((3-methyl-2-norbornyl)methyl)benzamide
Clocanfamidum (INN-Latin)
Clocanfamida (INN-Spanish)
Benzamide, 4-chloro-N-(2-hydroxyethyl)-N-((3-methylbicyclo(2.2.1)hept-2-yl)methyl)-
BENZAMIDE, p-CHLORO-N-(2-HYDROXYETHYL)-N-((3-METHYL-2-NORBORNYL)METHYL)-
Benzamide, 4-chloro-N-(2-hydroxyethyl)-N-((3-methylbicyclo(2.2.1)hept-2-yl)methyl)-(9CI)
18966-32-0
Clorocanfamide
4-chloro-N-(2-hydroxyethyl)-N-[(3-methyl-2-bicyclo[2.2.1]heptanyl)methyl]benzamide
SCHEMBL2111073
CHEMBL2104134
DTXSID60864867
p-Chlor-N-(2-hydroxyethyl)-N-(3-methylnorborn-2-ylmethyl)benzamide
NS00123186
Q27253568