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Pipradrol hydrochloride

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Identification
Molecular formula
C21H28Cl2N2O
CAS number
468-01-1
IUPAC name
4-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide;chloride
State
State

At room temperature, Pipradrol hydrochloride is in solid state.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
292.80
Boiling point (Kelvin)
565.95
General information
Molecular weight
390.48g/mol
Molar mass
390.4480g/mol
Density
1.1850g/cm3
Appearence

Pipradrol hydrochloride typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 4-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide;chloride

The solubility of 4-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide;chloride in various solvents is influenced by its unique chemical structure. This compound features both hydrophobic and hydrophilic components, leading to:

  • Moderate solubility in polar solvents: The presence of the chloride ion may enhance solubility in water and other polar solvents due to its ionic character.
  • Lower solubility in non-polar solvents: The bulky hydrophobic regions of the molecule likely result in decreased solubility in non-polar solvents.
  • pH-dependent solubility: The protonation state of the piperidine moiety can affect solubility; it may exhibit increased solubility at different pH levels.

Overall, it would be recommended to investigate specific solubility profiles under diverse experimental conditions to fully understand its behavior in various environments. As a guideline, it is often noted that:

"The compatibility of an ionic compound with aqueous solutions typically dictates its potential applications in biological systems."

These considerations will assist researchers in predicting its solubility and potential utility in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 4-Chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide; Chloride

This compound, known for its intricate structure, plays a significant role in various fields of chemistry and pharmacology. Below are some intriguing aspects worth noting:

  • Complex Structure: Featuring a piperidine ring and a chloro substituent, this compound showcases the vibrant diversity of organic chemistry.
  • Pharmacological Implications: Compounds with a similar framework are often studied for their potential therapeutic effects, including neuropharmacological activities.
  • Quaternary Ammonium Ion: The presence of the quaternary ammonium ion in its structure indicates unique interactions with biological membranes, which could enhance its bioavailability.
  • Research Tool: Due to its potential effects on neurotransmitter pathways, this compound can serve as a model for understanding the mechanisms of drug action.
  • Fine-Tuning Synthesis: The synthesis of this compound often requires specific conditions to optimize yield and purity, making it an interesting challenge for synthetic chemists.

In essence, the study of 4-chloro-N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)benzamide; chloride is not just about its chemical properties, but also about its potential applications in the realm of medicinal chemistry and beyond. As stated by chemist Robert H. Grubbs, “Chemistry is the art of understanding how every atom interacts with another,” which is perfectly illustrated by the intricate interplay found in this compound.

Synonyms
16297-41-9
4-Chloro-N-(alpha-(1-methyl-1-piperidinoethyl)benzilidene)benzamide hydrochloride
Benzamide, p-chloro-N-(alpha-(1-methyl-1-piperidinoethyl)benzilidene)-, monohydrochloride