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Clorazepate

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Identification
Molecular formula
C11H12ClNO3
CAS number
26412-87-3
IUPAC name
4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide
State
State

At room temperature, Clorazepate exists as a solid. It should be stored in a dry place to prevent degradation and maintain its efficacy.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
460.05
Boiling point (Kelvin)
733.20
General information
Molecular weight
227.67g/mol
Molar mass
227.4790g/mol
Density
1.3225g/cm3
Appearence

4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide appears as a crystalline solid. The color can range from off-white to yellow. It should be handled in a well-ventilated area to avoid inhalation of dust.

Comment on solubility

Solubility of 4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide

The solubility of 4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide is influenced by several factors, including its molecular structure and the presence of functional groups. Here are some key points to consider:

  • Polarity: The presence of polar groups, such as the amide functional group, can enhance solubility in polar solvents, like water.
  • Hydrophobic characteristics: The methoxyphenyl substituent introduces a hydrophobic aromatic character, which may limit solubility in highly polar solvents.
  • Solvent interactions: Solubility can vary significantly with different solvents. For example, while it may dissolve better in ethanol due to the ability to form hydrogen bonds, it might have lower solubility in non-polar solvents like hexane.
  • Temperature dependency: Increased temperature often increases solubility, potentially allowing more of the compound to dissolve in a given solvent.

In summary, while 4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide may exhibit moderate solubility in polar solvents, the aromatic and hydrophobic characteristics should be considered for optimal solvation. Understanding the solubility behavior is crucial for applications in formulation and chemical reactivity.

Interesting facts

Interesting Facts about 4-Chloro-N-(4-Methoxyphenyl)-3-Oxo-Butanamide

This compound, 4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide, is a fascinating example of how modifications to a simple amide structure can significantly alter its properties and potential applications. Here are some noteworthy points:

  • Pharmaceutical Potential: Compounds like this one often exhibit biological activity, making them valuable in drug discovery and development. The presence of both a chloro and a methoxy group suggests potential interactions with various biological targets.
  • Versatile Functional Groups: The combination of the chloro and methoxy substituents enhances the compound's chemical reactivity. This can lead to diverse synthetic pathways and derivatives that may exhibit unique characteristics.
  • Research Applications: 4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide can serve as a useful building block in organic synthesis, particularly in constructing more complex molecules for medicinal chemistry.
  • Mechanistic Studies: Investigating this compound's interactions can provide insights into reaction mechanisms, including nucleophilic substitutions and condensation reactions, which are fundamental concepts in organic chemistry.

As stated by renowned chemists, "The most exciting discoveries often come from exploring the unexpected potential of seemingly simple compounds." This compound embodies that spirit, illustrating the importance of each functional group in determining the overall behavior and utility in various scientific realms.

In summary, 4-chloro-N-(4-methoxyphenyl)-3-oxo-butanamide is not just a compound; it offers a canvas for exploration in both synthetic and applied chemistry, promising future innovations.

Synonyms
71919-02-3
Butanamide, 4-chloro-N-(4-methoxyphenyl)-3-oxo-
SCHEMBL6411466
DTXSID40274889