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Pirimicarb

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Identification
Molecular formula
C11H18ClN5O
CAS number
23103-98-2
IUPAC name
4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-pyrimidin-5-amine
State
State

At room temperature, Pirimicarb is in the solid state, commonly appearing as a white crystalline powder.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.00
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.00
General information
Molecular weight
238.70g/mol
Molar mass
238.6990g/mol
Density
1.3400g/cm3
Appearence

Pirimicarb appears as a white or off-white crystalline solid. It is often odorless and is typically found as a powder or granules form when used commercially.

Comment on solubility

Solubility of 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-pyrimidin-5-amine

The solubility of the compound 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-pyrimidin-5-amine (C11H18ClN5O) can be characterized multifactorially, making it a subject of interest in both laboratory and pharmaceutical settings. The structure of this compound provides insight into its possible interactions with solvents.

Several factors influence its solubility:

  • Polarity: The presence of the chlorine atom and the amine group contributes to its overall polarity, which often increases solubility in polar solvents.
  • Hydrogen Bonding: The amine functionalities can form hydrogen bonds with water, enhancing solubility. The imidazole ring may also participate in such interactions.
  • Hydrophobic Regions: The methoxy group and methyl chain introduce hydrophobic characteristics that could reduce solubility in very polar solvents.

Due to these characteristics, it may be more soluble in polar organic solvents while exhibiting limited solubility in non-polar environments. To illustrate:

  • **Higher solubility is expected in:** Ethanol, methanol, and dimethyl sulfoxide (DMSO).
  • **Lower solubility could be seen in:** Hexane or other non-polar solvents.

In summary, the solubility of this compound is influenced by its unique functional groups and structural features, providing opportunities for experimentation and application in various scientific fields. Understanding these solubility dynamics is essential for optimizing its use in relevant chemical contexts.

Interesting facts

Interesting Facts about 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-pyrimidin-5-amine

This compound, known for its complex structure and unique properties, is an intriguing example of a pyrimidine derivative. Here are some noteworthy aspects:

  • Pharmaceutical Applications: This compound is often studied for its potential applications in pharmacology. Its structure allows it to interact with various biological targets, making it a candidate for drug development.
  • Intermolecular Interactions: The presence of the chloro group and the methoxy substituent plays a significant role in how this molecule interacts with other compounds, potentially influencing its activity and solubility.
  • Key Substructures: The imidazole ring is particularly important in medicinal chemistry, as it is commonly found in many biologically active molecules. This versatility can lead to interesting insights into how modifications affect biological activity.
  • Cyclic Components: The 4,5-dihydro-imidazole moiety adds to the compound's stability and can influence its reactivity in various chemical contexts.
  • Synthesized Routes: The synthesis of pyrimidines, especially those with multiple functional groups, often involves an intricate series of reactions. Understanding these synthetic pathways can enhance knowledge in the field of organic chemistry.

As one delves deeper into the study of this compound, it's clear that the world of organic chemistry is filled with a myriad of possibilities. As chemists often say, “Structure dictates function,” and this compound is a prime example of how various substituents can lead to diverse applications and interactions in biological systems.

The study of 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-pyrimidin-5-amine continues to be a fascinating area of research, with ongoing investigations aimed at unlocking its full potential in medicinal chemistry and beyond.

Synonyms
MOXONIDINE
75438-57-2
Norcynt
Nucynt
4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
Cynt
Moxonidina
Physiotens
Moxonidinum
Moxonidinum [Latin]
Moxonidina [Spanish]
BE 5895
Moxonidine [INN]
BDF5895
BDF 5895
LY 326869
4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine
BE-5895
BDF5896
LY326869
CC6X0L40GW
BE5895
4-chloro-N-imidazolidin-2-ylidene-6-methoxy-2-methylpyrimidin-5-amine
Lomox
Moxonidine [USAN:INN:BAN]
DTXSID5045170
MOXONIDINE [MI]
5-Pyrimidinamine, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-
BDF-5895
BDF-5896
MOXONIDINE [USAN]
MOXONIDINE [MART.]
MOXONIDINE [WHO-DD]
CHEMBL19236
LY-326869
CHEBI:7009
moxonidin
DTXCID3025170
Monoxidine [common misspelling of Moxonidine]
MOXONIDINE [EP MONOGRAPH]
4-Chloro-5-(2-imidazolidinyldeneamino)-6-methoxy-2-methylpyrimidine
4-Chloro-5-(2-imidazolin-2-ylamino)-6-methoxy-2-methylpyrimidine
75438-57-2 (free base)
Moxonidinum (Latin)
NCGC00015649-02
Normoxocin
CAS-75438-57-2
MOXONIDINE (MART.)
MOXONIDINE (EP MONOGRAPH)
Normatens
4-chloro-N-(imidazolidin-2-ylidene)-6-methoxy-2-methylpyrimidin-5-amine
Moxonidine hydrochloride hydrate
Monoxidine (common misspelling of Moxonidine)
UNII-CC6X0L40GW
Fisiotens
SR-01000075981
Moxonidine; 4-Chloro-N-(imidazolidin-2-ylidene)-6-methoxy-2-methylpyrimidin-5-amine
Moxonidine (Standard)
Cynt (TN)
Moxonidine (USAN/INN)
Prestwick0_001016
Prestwick1_001016
Prestwick2_001016
Prestwick3_001016
Lopac-M-1559
Lopac0_000753
SCHEMBL49143
BSPBio_001171
MLS002222183
SPBio_003042
BPBio1_001289
GTPL12574
HY-B0374R
C02AC05
GLXC-10505
HMS1571K13
HMS2098K13
HMS2230B15
HMS3373O04
HMS3655B17
HMS3715K13
HMS3747A03
Moxonidine 1.0 mg/ml in Methanol
ALBB-022451
BCP23003
EX-A3409
HY-B0374
Tox21_110190
2-(6-Chloro-4-methoxy-2-methylpyrimidin-5-ylamino)-2-imidazoline
4-chloro-6-methoxy-2-methyl-5-(2-imidazolin-2-yl)aminopyrimidine
AC-637
BDBM50050093
MFCD22689455
PDSP1_000177
PDSP2_000176
s2066
STL419983
STL450991
AKOS015895873
AKOS015997932
Tox21_110190_1
AF-0062
CCG-204838
DB09242
SDCCGSBI-0050731.P002
NCGC00015649-01
NCGC00015649-04
NCGC00015649-05
NCGC00015649-08
NCGC00015649-17
NCGC00092355-02
FM165499
SMR000857402
AB00514003
M2660
NS00007154
SW196502-4
C07451
D05087
AB00514003-08
AB00514003_10
EN300-7360649
Q419944
SR-01000075981-7
BRD-K77771411-001-04-4
BRD-K77771411-001-12-7
BRD-K77771411-003-10-7
(4-Chloro-6-methoxy-2-methyl-pyrimidin-5-yl)-imidazolidin-2-ylidene-amine
4-chloro-N-(imidazolin-2-ylidene)-6-methoxy-2-methyl-5-pyrimidinamine
5-pyrimidinamine, 4-chloro-N-2-imidazolidinylidene-6-methoxy-2-methyl-
BDF5895;BDF-5895;BDF 5895;BE 5895; BE-5895; BE5895
2-(4-Chloro-6-methoxy-2-methyl-pyrimidin-5-ylamino)-4,5-dihydro-3H-imidazol-1-ium
5-Pyrimidinamine, 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl- (9CI)
(2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid
1008754-16-2
4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine;2-(6-Chloro-4-methoxy-2-methylpyrimidin-5-ylamino)-2-i midazoline
629-833-3