Skip to main content

Chlorothiazide

ADVERTISEMENT
Identification
Molecular formula
C7H5Cl3N4O2S
CAS number
58-94-6
IUPAC name
4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide
State
State

At room temperature, chlorothiazide is a solid. It is typically handled as a powder or in tablet form for pharmaceutical applications.

Melting point (Celsius)
340.00
Melting point (Kelvin)
613.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
295.10g/mol
Molar mass
295.0990g/mol
Density
1.8900g/cm3
Appearence

Chlorothiazide appears as a white or slightly yellow crystalline powder. It is odorless or may have a faint odor. The compound is usually available in a pure crystalline form for laboratory use.

Comment on solubility

Solubility of 4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide

When it comes to the solubility of 4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide, several key points must be considered:

  • Polarity: The presence of sulfonamide and chlorine substituents indicates a certain degree of polarity, which often enhances solubility in polar solvents such as water.
  • Solvent Interaction: This compound may demonstrate significantly different solubility profiles in various solvents, making it more soluble in polar protic solvents compared to non-polar solvents.
  • Temperature Sensitivity: Solubility can also depend on temperature; typically, increasing the temperature can lead to greater solubility in many cases.
  • pH Dependence: The solubility can be affected by the pH of the solution due to the potential ionization of the sulfonamide group.

As a general observation, compounds similar to 4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide tend to exhibit moderate to low solubility in aqueous solutions, yet their behavior can vastly differ with solvent choice and environmental conditions.

In conclusion, it is essential to evaluate the solubility in the context of the application and specific solvent conditions to fully understand the behavior of this compound in solution.

Interesting facts

Interesting Facts about 4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide

This compound, 4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide, is a fascinating example of a sulfonamide derivative with a triazine core. It belongs to a class of chemicals that has garnered attention for both its synthetic versatility and its biological activity. Here are some intriguing insights regarding this compound:

  • Biological Relevance: Compounds like this one are often studied for their potential antimicrobial properties. The sulfonamide moiety is known for its ability to inhibit bacterial growth, making these compounds significant in the field of medicinal chemistry.
  • Triazine Moiety: The triazine ring, which is part of the structure, lends the compound unique stability and reactivity, creating opportunities for further functionalization and application in agricultural chemistry.
  • Pesticide Development: Due to its chemical properties, this compound is researched for its potential use as a pesticide. Triazine derivatives can exhibit herbicidal activities, influencing how we manage crops and pests sustainably.
  • Pharmaceutical Applications: Researchers are excited about the potential applications of similar compounds in developing new pharmaceuticals that can target specific bacterial and viral pathways.

In essence, the study of 4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide not only deepens our understanding of chemistry but also enhances our exploration of potential applications in medicine and agriculture. As we continue to discover and investigate, compounds like this one remind us of the intersection between chemical structure and biological function.

Synonyms
4-chloro-N-(4,6-dichloro-1,3,5-triazin-2-yl)benzenesulfonamide
17752-71-5
DTXSID20274862