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4-Chlorobenzaldehyde

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Identification
Molecular formula
C7H5ClO
CAS number
104-88-1
IUPAC name
4-chlorobenzaldehyde
State
State

4-Chlorobenzaldehyde is typically found in a solid state at room temperature. It takes the form of crystalline powder.

Melting point (Celsius)
46.00
Melting point (Kelvin)
319.15
Boiling point (Celsius)
213.00
Boiling point (Kelvin)
486.15
General information
Molecular weight
140.57g/mol
Molar mass
140.5670g/mol
Density
1.2355g/cm3
Appearence

4-Chlorobenzaldehyde appears as white to pale yellow crystalline solid. It has a characteristic aromatic aldehyde smell which can be quite strong.

Comment on solubility

Solubility of 4-chlorobenzaldehyde

4-chlorobenzaldehyde, with the chemical formula C7H5ClO, exhibits interesting solubility characteristics that are influenced by its molecular structure.

This compound is:

  • Slightly soluble in water: Due to the presence of a polar carbonyl group, it has limited interaction with water molecules.
  • Soluble in organic solvents: It shows good solubility in non-polar organic solvents such as:
    • Ethyl acetate
    • Hexane
    • Chloroform

As with many organic compounds, the solubility of 4-chlorobenzaldehyde is a reflection of the principle of "like dissolves like." The non-polar characteristics of many of its preferred solvents facilitate its dissolution, while the hydrogen bond formation with water is less favorable, thus limiting solubility.

Overall, understanding these solubility patterns is crucial for applications where 4-chlorobenzaldehyde is utilized, as they dictate how the compound can be effectively handled and processed in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 4-Chlorobenzaldehyde

4-Chlorobenzaldehyde, also known as p-chlorobenzaldehyde, is an intriguing aromatic compound that has garnered significant attention in the fields of organic chemistry and material science. Here are some fascinating insights into this compound:

  • Aromatic Chemistry: As a derivative of benzaldehyde, 4-chlorobenzaldehyde showcases the characteristics of aromatic compounds, where the stability and reactivity are influenced by the aromatic ring. The presence of a chlorine atom remarkably affects its reactivity profile.
  • Industrial Applications: This compound is widely used in the synthesis of pharmaceuticals, agrochemicals, and dyes. Its aromatic properties contribute to the development of products such as insecticides and various fine chemicals.
  • Intermediary Role: 4-Chlorobenzaldehyde often serves as a key intermediate in organic synthesis. It is involved in the preparation of pharmaceuticals, molecular probes, and advanced materials. Its functionality allows for diverse reactions, including nucleophilic substitutions and cross-coupling reactions.
  • Structure-Activity Relationship: The chlorobenzaldehyde derivative illustrates the importance of substituents in designing new compounds. By studying how the chlorine atom modifies chemical properties, researchers can optimize compounds for improved biological activity.
  • Safety Considerations: While 4-chlorobenzaldehyde is useful, it should be handled with care. It is classified as an irritant and may have toxic effects if ingested or inhaled, emphasizing the importance of proper safety protocols in the lab.

In conclusion, 4-chlorobenzaldehyde plays a pivotal role in both academic research and industrial applications, making it a valuable compound in the realms of chemistry and beyond. Its unique features and practical uses anchor its importance within synthetic chemistry.

Synonyms
4-Chlorobenzaldehyde
104-88-1
P-CHLOROBENZALDEHYDE
Benzaldehyde, 4-chloro-
Benzaldehyde, p-chloro-
p-Chlorobenzenecarboxaldehyde
4-Chlorobenzenaldehyde
4-chloro-benzaldehyde
PARA-CHLOROBENZALDEHYDE
4-Chlorbenzaldehyd
4-chloro benzaldehyde
CCRIS 857
NSC 2078
EINECS 203-247-4
MFCD00003379
parachlorobenzaldehyde
UNII-E67727UP9Z
DTXSID2021860
AI3-52280
E67727UP9Z
4-chlorobenzoic aldehyde
NSC-2078
P-CHLOROPHENYLALDEHYDE
CHLOROBENZALDEHYDE, P-
4-FORMYLPHENYL CHLORIDE
CHLOROBENZALDEHYDE, 4-
DTXCID501860
1-CHLORO-4-FORMYLBENZENE
EC 203-247-4
PCAD
pChlorbenzaldehyd
4Chlorbenzaldehyd
pChlorobenzaldehyde
4-chlorobenzaldehye
4-chlorobezaldehyde
1Chlor4formylbenzol
4-Chlorobenzaldehyd
4Chlorobenzenaldehyde
4-formylchlorobenzene
p-chloro benzaldehyde
p-chloro-benzaldehyde
rho-chlorobenzaldehyde
Benzaldehyde, pchloro
Benzaldehyde, 4chloro
pChlorobenzoic aldehyde
4Chlorobenzoic aldehyde
p-chlorobenzoic aldehyde
(4-chlorophenyl)methanone
pChlorobenzenecarboxaldehyde
bmse001029
SCHEMBL1919
4-Chlorobenzaldehyde, 97%
CHEMBL1474
(4-chloro-phenyl)-methanone
NSC2078
BCP25775
STR00145
Tox21_200136
STK200392
AKOS000118927
CS-W008778
FC59856
PS-9029
NCGC00091804-01
NCGC00091804-02
NCGC00091804-03
NCGC00257690-01
AC-11571
CAS-104-88-1
DB-023682
NS00003543
EN300-18419
C06648
D77694
doi:10.14272/AVPYQKSLYISFPO-UHFFFAOYSA-N.1
Q2154695
Z57772447
F2190-0600
p-Chlorobenzenecarboxaldehyde; 4-Chlorobenzoic aldehyde; PCAD
203-247-4