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4-Chlorobenzohydrazide

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Identification
Molecular formula
C7H7ClN2O
CAS number
7392-44-3
IUPAC name
4-chlorobenzohydrazide
State
State

At room temperature, 4-Chlorobenzohydrazide is in a solid state, typically existing as small crystals or a crystalline powder.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.00
Boiling point (Celsius)
294.00
Boiling point (Kelvin)
567.00
General information
Molecular weight
170.60g/mol
Molar mass
170.5980g/mol
Density
1.3900g/cm3
Appearence

4-Chlorobenzohydrazide appears as a white to light-yellow crystalline solid. This compound may appear as a fine powder or small crystalline pieces that are typical of many synthesized organic compounds.

Comment on solubility

Solubility of 4-chlorobenzohydrazide

The solubility of 4-chlorobenzohydrazide can be influenced by several factors, including temperature, pH, and the nature of the solvent used. This compound is often described as being moderately soluble in various organic solvents but less so in water. Here are some key points regarding its solubility:

  • Solvents: Typically dissolves well in polar organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO).
  • Water Solubility: Limited solubility in water due to its hydrophobic aromatic ring structure, which hinders interactions with polar water molecules.
  • Temperature Effects: Increased temperature may enhance solubility in organic solvents, a common phenomenon among organic compounds.
  • pH Dependence: The presence of acidic or basic conditions can affect ionization and thus solubility, particularly if the compound can form salts.

In conclusion, while 4-chlorobenzohydrazide may not be highly soluble in water, it demonstrates a favorable solubility profile in organic solvents, making it suitable for various applications in organic chemistry. The solubility behavior is a testament to the compound's structural characteristics and interactions with different media.

Interesting facts

Interesting Facts about 4-Chlorobenzohydrazide

4-Chlorobenzohydrazide, a compound notable for its various applications, showcases a compelling blend of chemistry and functionality. Here are some intriguing aspects of this compound:

  • Versatile Applications: 4-Chlorobenzohydrazide is widely recognized for its role in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. Its structure allows for easy modification, making it a valuable intermediate for various chemical reactions.
  • Biological Activity: Research has suggested that 4-Chlorobenzohydrazide exhibits potential biological properties, including *antimicrobial* and *antioxidant* activities. These properties have sparked interest in the pharmaceutical field for developing new therapeutic agents.
  • Reactivity: The hydrazide functional group in 4-Chlorobenzohydrazide undergoes several types of reactions, such as hydrazone formation and acylation. These reactions expand its utility in synthetic organic chemistry, particularly in the construction of more complex molecules.
  • Environmental Significance: The compound's derivatives are often explored for their potential as biodegradable agents. As environmental concerns grow, compounds like 4-Chlorobenzohydrazide may lead the way in developing greener chemical processes.
  • Research Interest: Continuous studies are being conducted to explore the full scope of its reactivity and potential applications. The compound serves as a key player in the study of heterocyclic chemistry and materials science.

In summary, 4-Chlorobenzohydrazide is not just a compound of interest for its chemical properties but also serves as a stepping stone in advancing research in multiple fields. Its versatile applications and potential for innovative uses exemplify the dynamic nature of chemical studies.

Synonyms
4-Chlorobenzohydrazide
536-40-3
4-Chlorobenzoylhydrazine
Benzoic acid, 4-chloro-, hydrazide
p-Chlorobenzohydrazide
4-Chlorobenzoic acid hydrazide
p-Chlorobenzoylhydrazine
p-Chlorobenzoic hydrazide
p-Chlorobenzoyl hydrazide
4-Chlorobenzoyl hydrazide
p-Chlorobenzoic acid, hydrazide
4-Chlorobenzoic acid, hydrazide
P-CHLOROBENZHYDRAZIDE
NSC 54990
Benzoic acid, p-chloro-, hydrazide
EINECS 208-632-0
DTXSID40201817
DTXCID70124308
Benzoic acid, 4-chloro-, hydrazide (9CI)
Benzoic acid, p-chloro-, hydrazide (8CI)
208-632-0
inchi=1/c7h7cln2o/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4h,9h2,(h,10,11
4-Chlorobenzhydrazide
4-Chlorobenzoic Hydrazide
MFCD00007603
MLS000402191
4-Chloro-benzoic acid hydrazide
SMR000263809
4-chlorobenzene-1-carbohydrazide
benzoylhydrazine, P-chloro
4-chlorobenzenecarbohydrazide
4ClPhCON2
4-chloro-benzhydrazide
Opera_ID_1071
(p-chlorobenzoyl)hydrazine
benzohydrazide, 4-chloro-
(4-Chlorobenzoyl)hydrazine
4-Chlorobenzhydrazide, 98%
SCHEMBL165164
CHEMBL125812
HMS2529I20
NSC54990
STR01242
BBL003589
NSC-54990
STK039718
AKOS000194880
FC36734
SB85905
NCGC00246092-01
SY035573
DB-052369
C2060
CS-0142936
NS00032801
EN300-17501
Z56945552
F1171-0133