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4-Chlorobutane-1-sulfonamide

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Identification
Molecular formula
C4H10ClNO2S
CAS number
171262-17-2
IUPAC name
4-chlorobutane-1-sulfonamide
State
State

4-Chlorobutane-1-sulfonamide is in a solid state at room temperature.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.00
Boiling point (Celsius)
304.00
Boiling point (Kelvin)
577.00
General information
Molecular weight
187.64g/mol
Molar mass
187.6440g/mol
Density
1.3210g/cm3
Appearence

4-Chlorobutane-1-sulfonamide is typically found as a solid with a crystalline appearance. The color of this compound is generally white to off-white. It is known for its use in various chemical syntheses and research applications.

Comment on solubility

Solubility of 4-chlorobutane-1-sulfonamide

4-chlorobutane-1-sulfonamide, characterized by its sulfonamide group, exhibits notable solubility in various solvents. Primarily, its solubility can be summarized as follows:

  • Water: 4-chlorobutane-1-sulfonamide is generally soluble in water due to its polar nature, enhanced by the presence of the sulfonamide functional group.
  • Organic Solvents: This compound shows moderate solubility in organic solvents such as methanol and ethanol, which can be attributed to its hydrophobic alkyl chain.
  • Non-polar Solvents: However, it exhibits limited solubility in non-polar solvents due to the polarity of the sulfonamide group.

In conclusion, the solubility of 4-chlorobutane-1-sulfonamide is influenced by the balance between its polar and non-polar characteristics. As with many sulfonamides, solubility is often enhanced in polar solvents, making it an interesting compound for various applications in biochemical research and pharmaceutical formulations.

Interesting facts

Interesting Facts about 4-Chlorobutane-1-sulfonamide

4-Chlorobutane-1-sulfonamide is a fascinating compound that plays a significant role in various fields of chemistry and medicinal applications. Here are some noteworthy aspects to consider:

  • Structure and Functionality: The compound features a sulfonamide functional group, which is a key component in many pharmaceuticals. This group is often responsible for the compound's biological activity, making it a focus of study in medicinal chemistry.
  • Biological Applications: Compounds containing sulfonamide moieties, including 4-chlorobutane-1-sulfonamide, are known for their antibacterial properties. They have been used to develop drugs that combat infections caused by a variety of bacteria.
  • Synthesis: The synthesis of this compound involves the reaction of chlorobutane with a sulfonamide precursor. This process is not only an excellent example of organic synthesis but also highlights the versatility of alkyl halides in chemical reactions.
  • Research Relevance: Due to its unique chemical structure, 4-chlorobutane-1-sulfonamide is often studied in the context of drug design and development, as researchers explore new derivatives that may enhance therapeutic efficacy.
  • Environmental Considerations: The stability of sulfonamides in various conditions raises questions about their environmental impact, especially as they can persist in the environment and potentially affect microbial communities.

As a compound that bridges organic chemistry and pharmacology, 4-chlorobutane-1-sulfonamide serves as an excellent example of how intricate chemical design can yield substances with significant medical importance. As we delve deeper into the study of such compounds, we may uncover novel applications that could benefit both healthcare and environmental science.

Synonyms
4-chlorobutane-1-sulfonamide
3144-06-7
1-BUTANESULFONAMIDE, 4-CHLORO-
4-Chloro-1-butanesulfonamide
Chlorbutansulfamid
Chlorbutansulfamid [German]
BRN 1905512
DTXSID40185365
DTXCID50107856
848-912-5
4-chlorobutanesulfonamide
starbld0019938
4-chlorobutane-sulfonamide
4-chloro-butane-1-sulfonamide
SCHEMBL3858379
JTGPQGWEMUOOCR-UHFFFAOYSA-N
EN300-4276464