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4-Chlorobutyric acid

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Identification
Molecular formula
C4H7ClO2
CAS number
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IUPAC name
4-chlorobutanoic acid
State
State

At room temperature, 4-Chlorobutyric acid most commonly exists as a liquid. However, it can form crystalline solids under certain conditions, influenced by its melting point.

Melting point (Celsius)
40.00
Melting point (Kelvin)
313.15
Boiling point (Celsius)
208.50
Boiling point (Kelvin)
481.65
General information
Molecular weight
122.55g/mol
Molar mass
122.5500g/mol
Density
1.2050g/cm3
Appearence

4-Chlorobutyric acid typically appears as a colorless to light yellow liquid. It has a pungent, unpleasant odor characteristic of chlorinated carboxylic acids. This compound can also be found in a crystalline form under certain conditions.

Comment on solubility

Solubility of 4-Chlorobutanoic Acid

4-Chlorobutanoic acid, with the chemical formula C4H7ClO2, exhibits a notable solubility profile that can be summarized as follows:

  • Polar Nature: The presence of the carboxylic acid (-COOH) group contributes significantly to the compound's polarity, enhancing its interaction with polar solvents such as water.
  • Water Solubility: 4-Chlorobutanoic acid is moderately soluble in water, primarily due to hydrogen bonding capabilities of the carboxylic acid moiety, which can form favorable interactions with water molecules.
  • Solvent Dependency: Its solubility can vary in different solvents; for instance, it is generally more soluble in polar aprotic solvents compared to non-polar organic solvents.
  • Temperature Influence: Like many organic compounds, solubility can increase with temperature, making heating a useful strategy for dissolving the compound in various solvents.

Overall, understanding the solubility properties of 4-chlorobutanoic acid is essential for applications in organic synthesis and pharmaceuticals, where effective dissolution can greatly influence reaction rates and product yields.

Interesting facts

Interesting Facts about 4-Chlorobutanoic Acid

4-Chlorobutanoic acid is an intriguing compound that exhibits unique properties and applications in various fields of chemistry. Here are some key facts that highlight its significance:

  • Structure and Isomerism: The presence of a chlorine atom at the fourth carbon in the butanoic acid chain introduces interesting stereochemistry. This halogen substitution leads to several isomers, contributing to the diversity of organic compounds.
  • Reactivity: As a carboxylic acid, 4-chlorobutanoic acid readily undergoes reactions typical of acids. It can participate in esterification, amide formation, and various nucleophilic substitution reactions, making it a versatile intermediate in synthetic organic chemistry.
  • Biological Importance: This compound can be utilized as a building block in the synthesis of pharmaceuticals and agrochemicals. Its derivatives may exhibit biological activity, raising interest in its potential use in drug discovery and development.
  • Environmental Considerations: Like many halogenated compounds, the environmental impact of 4-chlorobutanoic acid is an important consideration. Concentration levels in ecosystems and their effects on organic life warrant further investigation.
  • Historical Context: Chlorinated organic compounds have been studied extensively since the early 20th century, marking a significant evolution in both industrial manufacturing and laboratory research.

In summary, 4-chlorobutanoic acid serves not only as a fundamental component in various chemical syntheses but also as a starting point for exploring more complex molecules. Its unique structural features and reactivity continue to inspire research and innovation in the fields of organic chemistry and materials science.

Synonyms
4-Chlorobutanoic acid
4-CHLOROBUTYRIC ACID
Butanoic acid, 4-chloro-
Gammachlorobutyric acid
NSC 6391
Cl(CH2)3COOH
EINECS 210-977-7
NSC 76578
.gamma.-Chloro-n-butyric acid
DTXSID8060828
gamma-Chloro-n-butyric acid
DTXCID9043485
210-977-7
inchi=1/c4h7clo2/c5-3-1-2-4(6)7/h1-3h2,(h,6,7
iplkgjhgwcvsog-uhfffaoysa-n
627-00-9
Butyric acid, 4-chloro-
gamma-Chlorobutyric acid
4-chlorobutanoicacid
4-chloro-butyric acid
MFCD00002818
.gamma.-Chlorobutyric acid
NSC-6391
NSC-76578
4-Chloro-n-butyric Acid
SCHEMBL34825
4-Chlorobutyric acid, 99%
FW74RY75G3
NSC6391
NSC76578
AKOS009100462
CS-W013545
PB47766
BS-23241
FC164688
SY051529
C0651
NS00035132
EN300-24805
F19286