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4-Chlorocyclohexanol

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Identification
Molecular formula
C6H11ClO
CAS number
1192-37-6
IUPAC name
4-chlorocyclohexanol
State
State

At room temperature, 4-Chlorocyclohexanol is found in a solid state. This state is due to its melting point being relatively high compared to room temperature.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
213.50
Boiling point (Kelvin)
486.65
General information
Molecular weight
148.61g/mol
Molar mass
148.6210g/mol
Density
1.1690g/cm3
Appearence

4-Chlorocyclohexanol is typically a crystalline solid. The compound can also be obtained in the form of a powder. It is mostly white or off-white in appearance. Its appearance can slightly vary depending on the purity and form in which it is prepared.

Comment on solubility

Solubility of 4-Chlorocyclohexanol

4-Chlorocyclohexanol, with the chemical formula C6H11ClO, exhibits interesting solubility characteristics that are influenced by its molecular structure.

General Solubility Characteristics

In general, the solubility of 4-chlorocyclohexanol can be described as follows:

  • Polarity: The presence of the hydroxyl group (-OH) makes 4-chlorocyclohexanol polar, which allows it to interact favorably with polar solvents.
  • Solvent Compatibility: It is likely to be soluble in:
    • Water (to some extent, given the polar -OH group)
    • Alcohols
    • Some organic solvents such as acetone, due to similar polar characteristics
  • Limiting Factors: However, the solubility may be limited by:
    • The bulky cyclohexane ring structure, which makes it less compatible with highly polar solvents.
    • Hydrophobic interactions resulting from the chlorinated cyclohexane moiety.

As a result, the importance of considering both polarity and molecular structure cannot be overstated when predicting the solubility behavior of 4-chlorocyclohexanol.

Conclusion

In summary, 4-chlorocyclohexanol demonstrates moderate solubility in various solvents, influenced by its polar -OH group and its chlorinated cyclohexane structure. It's essential to evaluate specific solvent properties for optimal dissolution.

Interesting facts

Interesting Facts about 4-chlorocyclohexanol

4-chlorocyclohexanol is a fascinating compound that belongs to the class of organic chemicals known as alcohols. It is particularly noteworthy for several reasons:

  • Functional Group Diversity: This compound features both a chlorinated substituent and a hydroxyl group, making it a versatile molecule in organic synthesis.
  • Applications: It is commonly used in the development of pharmaceuticals and agrochemicals, serving as a building block for more complex structures.
  • Environmentally Relevant: The presence of chlorine in its structure often raises considerations regarding its environmental impact and the need for proper handling due to potential toxicity.
  • Research Interest: Researchers are interested in studying 4-chlorocyclohexanol for its unique stereochemistry, which can lead to differences in reactivity and biological activity.
  • Chemical Behavior: Its behavior in reactions such as nucleophilic substitutions and elimination provides insight into the effects of substituents in cyclic alcohols.

As one prominent organic chemist eloquently put it, "The beauty of organic chemistry lies in the subtle interplay between structure and function." This is clearly exemplified in the properties and behaviors of 4-chlorocyclohexanol.

Overall, 4-chlorocyclohexanol's combination of structural features and its implications in various fields makes it a compound worthy of study and appreciation.

Synonyms
4-Chlorocyclohexanol
30485-71-3
1-Chloro-4-Hydroxycyclohexane
DTXSID40184555
RefChem:521980
DTXCID80107046
805-059-3
4-chlorocyclohexan-1-ol
29538-77-0
trans-4-Chlorocyclohexanol
Cyclohexanol, 4-chloro-
trans-4-Chloro-cyclohexanol
Cyclohexanol, 4-chloro-, trans-
MFCD00038713
Rel-(1r,4r)-4-chlorocyclohexan-1-ol
4-Chlorocyclohexanol #
cis-4-chlorocyclohexanol
(E)-4-Chlorocyclohexanol
trans--4-Chlorocyclohexanol
4-hydroxy-cyclohexyl chloride
SCHEMBL1766735
SCHEMBL1766740
SCHEMBL10542869
SCHEMBL10543208
SCHEMBL27893501
HVPIAXWCSPHTAY-OLQVQODUSA-N
DTXSID901031186
trans-4-hydroxy-cyclohexyl chloride
SBB007863
AKOS006228549
SB84297
FC176167
SY413096
DB-047789
CS-0032779
CS-0497684
NS00114002
ST50828268
4-Chlorocyclohexan-1-ol, mixture of diastereomers
F329686