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4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane

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Identification
Molecular formula
C6H11ClO2
CAS number
35838-35-0
IUPAC name
4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane
State
State

At room temperature, 4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane is typically found as a liquid.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
150.61g/mol
Molar mass
150.6160g/mol
Density
1.0610g/cm3
Appearence

This compound is often found in liquid form and is colorless. It may have a slight odor that is characteristic of chlorinated dioxolanes.

Comment on solubility

Solubility of 4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane

The solubility of 4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane is an intriguing topic, particularly due to its unique molecular structure. Understanding the solubility characteristics can offer insights into its potential applications and interactions in various environments.

In terms of solubility:

  • Polarity: The presence of both the chloromethyl group and the dioxolane ring contributes to the overall polarity of the compound. This affects its solubility in polar solvents.
  • Solvent Compatibility: It is generally more soluble in polar organic solvents, such as:
    • Alcohols
    • Esters
    • Some ethers
  • Water Solubility: Due to its structural features, it has limited solubility in water, making it more compatible with organic phases.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature, potentially affecting its use in various applications.

In conclusion, while 4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane exhibits some solubility in organic solvents, its limited water solubility highlights the importance of selecting appropriate solvents for its use. As a quotation often states, "The solvent dictates the reaction," reminding us of the critical role solubility plays in chemical interactions.

Interesting facts

Interesting Facts about 4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane

This intriguing compound, known as 4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane, possesses unique structural features making it an interesting subject in organic chemistry. As a member of the dioxolane family, it features a five-membered ring that includes two oxygen atoms, which significantly contributes to its chemical properties.

Key Features:

  • Versatile Intermediate: This compound serves as an important intermediate in synthetic organic chemistry, often utilized in the manufacture of various pharmaceuticals and fine chemicals.
  • Reactive Group: The presence of a chloromethyl group within its structure makes it highly reactive, allowing it to participate in numerous nucleophilic substitution reactions.
  • Use in Synthesis: Its unique structure enables the transformation into more complex molecules, facilitating the development of new materials and biologically active compounds.

Furthermore, the dioxolane ring system can exhibit properties such as enhanced *stability* and *selectivity* in chemical reactions, making it an attractive scaffold for medicinal chemistry research.

In studying this compound, scientists often emphasize the potential to explore its reactivity patterns and applications in different chemical environments. As pointed out by leading chemists, "Understanding the reactivity of such compounds opens doors to novel discoveries." This is particularly true for those venturing into the fields of drug development and material science.

In summary, 4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane stands out as a versatile and valuable compound in the realm of organic synthesis, enriching the toolkit of chemists and researchers alike.

Synonyms
4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane
1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl-
BRN 0104463
EINECS 224-452-5
AI3-17556
UNII-0366925SM9
0366925SM9
DTXSID60884065
5-19-01-00085 (Beilstein Handbook Reference)
1-CHLORO-2,3-O-ISOPROPYLIDENEPROPANE
DTXCID101023537
(+-)-4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE, (+-)-
bnpotxlwpzoesz-uhfffaoysa-n
4362-40-7
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
MFCD00046097
4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane, (+/-)-
(S)-(-)-4-chloromethyl-2,2-dimethyl-1,3-dioxolane
(+/-)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane
MFCD00273365
MFCD00273371
1,3-Dioxolane, 4-(chloromethyl)-2,2-dimethyl-; (+/-)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane; 1-Chloro-2,3-O-isopropylidenepropane
R-Chloropropanediol acetonide
SCHEMBL150257
EAA36240
AKOS005203140
SB37184
SB44724
SB46740
AS-47211
SY014847
SY016487
SY038108
2,2-dimethyl-4-chloromethyl-1,3-dioxolane
CS-0134037
NS00045917
4-chloromethyl-2,2-dimethyl-[1,3]dioxolane
EN300-122587
F12669
4-(chloromethyl)-2,2-dimethyl-[1,3]dioxolane
(S)-2,2-Dimethyl-4-Chloromethyl-1,3-Dioxolane
4-Chloromethyl-2,2-dimethyl-1,3-dioxolane, 97%
Q27247531
(S)-(+)-4-Chloromethyl-2,2-dimethyl-­1,3-dioxolane
4-Chloromethyl-2 pound not2-dimethyl-1 pound not3-dioxolane
4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane 100 microg/mL in Acetonitrile