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Oxymetazoline

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Identification
Molecular formula
C16H24ClN3O
CAS number
1491-59-4
IUPAC name
(4-chlorophenyl)-(4,5-dihydro-1H-imidazol-2-yl)-(2-pyridyl)methanol
State
State

At room temperature, Oxymetazoline is typically found in a solid state as a powder.

Melting point (Celsius)
139.00
Melting point (Kelvin)
412.15
Boiling point (Celsius)
358.30
Boiling point (Kelvin)
631.50
General information
Molecular weight
340.83g/mol
Molar mass
340.8290g/mol
Density
1.1300g/cm3
Appearence

Oxymetazoline appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of (4-chlorophenyl)-(4,5-dihydro-1H-imidazol-2-yl)-(2-pyridyl)methanol

The solubility of the compound (4-chlorophenyl)-(4,5-dihydro-1H-imidazol-2-yl)-(2-pyridyl)methanol is influenced by several key factors, including its molecular structure and the presence of polar functional groups. Here are some important aspects to consider:

  • Polar functional groups: The presence of the hydroxyl group (-OH) typically enhances hydrophilicity, suggesting that this compound may dissolve well in polar solvents, such as water.
  • Aromatic substituents: The chlorophenyl and pyridyl rings can contribute to hydrophobic interactions, which may decrease solubility in water but increase solubility in organic solvents.
  • Hydrogen bonding: The ability of the hydroxyl group to engage in hydrogen bonding can facilitate solubility in polar environments.
  • Overall solubility: It is likely that this compound exhibits moderate solubility in polar solvents, with potentially higher solubility in organic solvents due to the hydrophobic character of the aromatic rings.

Given these considerations, it's reasonable to suggest that the solubility of (4-chlorophenyl)-(4,5-dihydro-1H-imidazol-2-yl)-(2-pyridyl)methanol may vary widely depending on the solvent used. Testing in various solvents will provide the most accurate understanding of its solubility characteristics.

Interesting facts

Interesting Facts about (4-chlorophenyl)-(4,5-dihydro-1H-imidazol-2-yl)-(2-pyridyl)methanol

This intriguing compound combines various functional groups and demonstrates a range of potential applications in chemical research and medicinal chemistry. Here are some fascinating insights:

  • Diverse Structure: The compound features a unique combination of a chlorophenyl group, a dihydroimidazole, and a pyridine derivative, allowing it to participate in various chemical reactions and interactions.
  • Biological Significance: Compounds containing imidazole and pyridine rings have been extensively studied for their pharmacological activities, including antimicrobial, anti-inflammatory, and anticancer properties.
  • Ligand Properties: Given its complex structure, this compound may serve as an effective ligand in coordination chemistry, potentially forming complexes with transition metals.
  • Synthetic Potential: The synthesis of this type of compound contributes to the development of new methodologies in organic synthesis, paving the way for innovative medicinal agents.
  • Research Opportunities: The versatility of this compound makes it an exciting subject for ongoing research, particularly in the fields of organometallic chemistry and material science.

As a chemical scientist or student, delving into the properties and applications of such compounds can offer valuable insights into the molecular design of new therapeutics and functional materials. The combination of different aromatic and heterocyclic systems in a single molecule presents a fertile ground for innovative discoveries in both academic and industrial contexts.

Synonyms
Dazadrol
47029-84-5
Dazadrol [INN]
(4-chlorophenyl)-(4,5-dihydro-1H-imidazol-2-yl)-pyridin-2-ylmethanol
alpha-(p-Chlorophenyl)-alpha-2-imidazolin-2-yl-2-pyridinemethanol
9U27285V5R
Dazadrolum
Dazadrolum [INN-Latin]
UNII-9U27285V5R
EINECS 256-292-7
orb2814944
SCHEMBL2110858
CHEMBL2110607
DTXSID60866124
DITYEPYMBCHKLF-UHFFFAOYSA-N
2-Pyridinemethanol, .alpha.-(4-chlorophenyl)-.alpha.-(4,5-dihydro-1H-imidazol-2-yl)-
NS00058163
Q27273221
2-Pyridinemethanol, alpha-(p-chlorophenyl)-alpha-2-imidazolin-2-yl-
.ALPHA.-(P-CHLOROPHENYL)-.ALPHA.-2-IMIDAZOLIN-2-YL-2-PYRIDINEMETHANOL