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4-Chlorodiphenylmethanol

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Identification
Molecular formula
C13H11ClO
CAS number
776-43-0
IUPAC name
(4-chlorophenyl)-phenyl-methanol
State
State
At room temperature, it is a solid and generally stable under recommended storage conditions, away from moisture and light.
Melting point (Celsius)
79.00
Melting point (Kelvin)
352.15
Boiling point (Celsius)
344.00
Boiling point (Kelvin)
617.15
General information
Molecular weight
204.68g/mol
Molar mass
204.6640g/mol
Density
1.1990g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder or solid. It is not soluble in water but may dissolve in organic solvents.

Comment on solubility

Solubility of (4-chlorophenyl)-phenyl-methanol

The solubility of (4-chlorophenyl)-phenyl-methanol can be influenced by several factors due to its unique structure. This compound is characterized by its aromatic rings and the presence of a hydroxyl group, which play a crucial role in determining how it behaves in various solvents.

Key Factors Affecting Solubility:

  • Polarity: The hydroxyl (-OH) group introduces some polarity to the molecule, which can enhance solubility in polar solvents like water.
  • Saturation: The compound's multiple aromatic rings can lead to a decrease in solubility in non-polar solvents due to increased hydrophobic interactions.
  • Temperature: As with many organic compounds, solubility generally increases with temperature, allowing for greater interaction with solvents.
  • Presence of Substituents: The chlorine substituent can also impact the molecule's overall behavior in a solvent by altering electron distribution and intermolecular forces.

In general, one might expect that:

  • The compound could exhibit moderate solubility in polar solvents, given the hydroxyl group.
  • Limited solubility in non-polar solvents due to the complexity of the aromatic structure.

As a rule of thumb, the solubility of organic compounds often reflects their molecular structure, so evaluating (4-chlorophenyl)-phenyl-methanol in various solvents will provide further insight. Understanding these aspects can lead to optimized applications in pharmaceuticals and other chemical disciplines.

Interesting facts

Interesting Facts about (4-Chlorophenyl)-Phenyl-Methanol

(4-Chlorophenyl)-phenyl-methanol is a fascinating compound that showcases the complex interplay between structure and function in organic chemistry. This compound, often referred to in conjunction with its various applications, opens up discussions on its relevance in both industrial and academic settings.

Applications

  • Pharmaceutical Industry: This compound can serve as an intermediate in the synthesis of pharmaceutical agents. Its unique structure allows for modifications that can lead to the development of drugs with specific therapeutic effects.
  • Biochemical Studies: Given its aromatic nature, (4-chlorophenyl)-phenyl-methanol can be useful in biochemical assays, particularly when studying the interactions of small molecules with biological targets.
  • Research on Chlorinated Compounds: The presence of chlorine in its structure makes it a valuable subject for studies involving environmental impact, especially in the context of chlorinated organic contaminants.

Structure and Properties

The structure of (4-chlorophenyl)-phenyl-methanol features a unique combination of phenyl groups that contributes to its stability and reactivity. Key characteristics include:

  • Aromaticity: The compound possesses multiple aromatic rings, which imparts a degree of stability due to delocalized π-electrons.
  • Electron-Withdrawing Group: The chlorine atom attached to one of the phenyl rings acts as an electron-withdrawing group, influencing the reactivity of the compound in chemical reactions.

Safety Considerations

As with many organic compounds, considerations for safety and handling are essential. It's important to remember:

  • Proper personal protective equipment (PPE) should be worn when working with the compound.
  • Always handle with care, adhering to safety protocols to minimize exposure and environmental impact.

In conclusion, (4-chlorophenyl)-phenyl-methanol is not just another organic compound; it represents the intricate world of chemistry where structure directly influences function and application. From its synthetic utility in pharmaceuticals to its role in environmental discussions, this compound embodies the dynamic nature of chemical research.

Synonyms
4-Chlorobenzhydrol
119-56-2
(4-Chlorophenyl)(phenyl)methanol
P-CHLOROBENZHYDROL
Chlorobenzhydrol
Benzhydrol, 4-chloro-
(4-Chlorophenyl)phenylmethanol
Benzhydrol, p-chloro-
(4-chlorophenyl)-phenylmethanol
Benzenemethanol, 4-chloro-.alpha.-phenyl-
Chlorbenzhydrol
Benzenemethanol, 4-chloro-alpha-phenyl-
4-Chlorodiphenylmethanol
4-Chlorobenzhydryl alcohol
4-Chlorodiphenylcarbinol
V5V8VYQ65X
MFCD00004491
NSC 59990
EINECS 204-333-4
NSC-59990
4-CBH
AI3-20881
CHEBI:35091
DTXSID50870472
EC 204-333-4
(+/-)-4-CHLOROBENZHYDROL
4-CHLORO-.ALPHA.-PHENYLBENZENEMETHANOL
.ALPHA.-(4-CHLOROPHENYL)BENZYL ALCOHOL
4-Chloro Benzhydrol (Meclozine EP Impurity B)
(S)-4-chloro-diphenylmethanol
MECLOZINE DIHYDROCHLORIDE IMPURITY B [EP IMPURITY]
4-Chloro benzhydrol
UNII-V5V8VYQ65X
MECLOZINE DIHYDROCHLORIDE IMPURITY B (EP IMPURITY)
4-Chlorobenzohydrol
Meclozine impurity B
4-Chlorodiphenyl carbinol
4-Chlorobenzhydrol, 98%
CBHP [USP IMPURITY]
SCHEMBL477379
Benzhydrol, 4-chloro-(8CI)
CHEMBL2251568
AJYOOHCNOXWTKJ-UHFFFAOYSA-
DTXCID10818193
(4-Chloro-phenyl)-phenyl-methanol
NSC59990
STL450937
AKOS000121493
AKOS016844008
alpha-(4-chlorophenyl)-benzyl alcohol
FC39731
AC-15870
AS-62173
SY032425
4-CHLORO-ALPHA-PHENYLBENZENEMETHANOL
DB-041481
DB-241602
ALPHA-(4-CHLOROPHENYL)BENZYL ALCOHOL
C0989
CS-0186996
NS00006294
4-Chlorobenzhydryl alcohol;4-Chlorobenzhydrol
EN300-21103
Q27116410
Z104491516
Meclozine impurity B, European Pharmacopoeia (EP) Reference Standard
InChI=1/C13H11ClO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13,15H