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4-Chlorobenzophenone

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Identification
Molecular formula
C13H9ClO
CAS number
134-85-0
IUPAC name
(4-chlorophenyl)-phenyl-methanone
State
State

At room temperature, 4-Chlorobenzophenone is typically found in a solid state.

Melting point (Celsius)
77.00
Melting point (Kelvin)
350.15
Boiling point (Celsius)
324.00
Boiling point (Kelvin)
597.15
General information
Molecular weight
202.66g/mol
Molar mass
202.6600g/mol
Density
1.2123g/cm3
Appearence

4-Chlorobenzophenone is a white to off-white crystalline solid. It has a distinct aromatic odor and is visually characterized by its crystalline texture.

Comment on solubility

Solubility of (4-chlorophenyl)-phenyl-methanone

The solubility of (4-chlorophenyl)-phenyl-methanone, also known as benzyl 4-chlorobenzophenone or simply 4-chlorobenzophenone, is an interesting topic for discussion among chemists.

This compound is largely characterized by its hydrocarbon framework which affects its interactions with solvents. Here are some key points regarding its solubility:

  • Polarity: The presence of the polar carbonyl group (C=O) contributes to its overall polarity, impacting solubility in different solvents.
  • Solvent interactivity: It exhibits moderate solubility in organic solvents like ethanol and acetone.
  • Solvent categorization: It is less soluble in highly polar solvents, indicating a preference for less polar environments.

As a general rule, like dissolves in like, so:

  1. Polar solvents: Limited solubility due to the nonpolar aromatic system.
  2. Non-polar solvents: Better solubility as they complement the compound’s nonpolar regions.

Overall, the solubility of (4-chlorophenyl)-phenyl-methanone showcases the fascinating balance between its structural characteristics and the properties of solvent systems. As such, understanding these interactions is essential for applications in organic chemistry and materials science.

Interesting facts

Interesting Facts about (4-chlorophenyl)-phenyl-methanone

(4-chlorophenyl)-phenyl-methanone, commonly referred to as a derivative of benzophenone, is an intriguing compound in organic chemistry with various applications in the fields of material science and pharmaceuticals. Here are some engaging insights about this compound:

  • Structural Diversity: The compound features an extensive structure involving multiple aromatic rings. This structure is known for its ability to contribute to the compound's unique chemical properties and reactivity.
  • Applications: Due to its photostability, (4-chlorophenyl)-phenyl-methanone is often used in the formulation of sunscreens and photoinitators in polymer chemistry. Its capability to absorb UV radiation makes it valuable in protective coatings.
  • Biological Relevance: Studies have shown that derivatives of this compound possess promising biological activities, including antibacterial and anticancer properties. This opens avenues for further research into its pharmacological applications.
  • Synthetic Pathways: The synthesis of (4-chlorophenyl)-phenyl-methanone can be achieved through various methods, commonly involving Friedel-Crafts acylation reactions. This illustrates the versatility of electrophilic aromatic substitution reactions in organic synthesis.
  • Environmental Considerations: Like many aromatic compounds, studies are being conducted to understand the environmental impact of (4-chlorophenyl)-phenyl-methanone. Investigating its degradation products and their potential toxicity is crucial for environmental safety.

In summary, (4-chlorophenyl)-phenyl-methanone is not just a simple aromatic ketone; it is a compound with potential applications across chemistry, biology, and materials science. Understanding its properties and functions can lead to innovations in various industrial and pharmaceutical processes. As stated by a renowned chemist, *“In the world of molecules, the potential for discovery is limitless.”*

Synonyms
4-CHLOROBENZOPHENONE
134-85-0
(4-Chlorophenyl)(phenyl)methanone
p-Chlorobenzophenone
Methanone, (4-chlorophenyl)phenyl-
p-CBP
(4-chlorophenyl)-phenylmethanone
Benzophenone, 4-chloro-
4-chloro benzophenone
para-Chlorobenzophenone
(4-chlorophenyl)phenylmethanone
4-Benzoylphenyl chloride
UNII-WIH1IZ728U
p-Chlorophenyl phenyl ketone
4-chlorophenyl phenyl ketone
WIH1IZ728U
MFCD00000622
DTXSID2051687
HSDB 2740
NSC 2872
NSC-2872
CLEMASTINE (M2)
EINECS 205-160-7
4-CBP
Cetirizine Impurity (4-Chlorobenzophenone)
AI3-00705
DTXCID5030242
PHENYL 4-CHLOROPHENYL KETONE
4-CHLOROBENZOPHENONE [USP-RS]
4-CHLOROPHENYL-PHENYL METHANONE
4-Chlorobenzophenone(Chunks or pellets or flake)
MECLOZINE DIHYDROCHLORIDE IMPURITY C [EP IMPURITY]
4-CHLOROBENZOPHENONE (USP-RS)
MECLOZINE DIHYDROCHLORIDE IMPURITY C (EP IMPURITY)
pChlorobenzophenone
Meclozine Hydrochloride Imp. C (EP); Meclozine Imp. C (EP); 4-Chlorobenzophenone; (4-Chlorophenyl)phenylmethanone; Meclozine Dihydrochloride Impurity C; Meclozine Impurity C
paraChlorobenzophenone
Benzophenone, 4chloro
4-Chlorobenzophenone, 99%
SCHEMBL50462
phenyl-(4-chlorophenyl)-ketone
Benzophenone, 4-chloro-(8CI)
CHEMBL3560455
Methanone, (4chlorophenyl)phenyl
NSC2872
CHEBI:167846
BCP27841
STR01449
Tox21_304009
(4-Chlorophenyl)(phenyl)methanone #
STL453116
AKOS000119405
CS-W004344
FC10726
PS-7925
NCGC00357224-01
AC-23664
CAS-134-85-0
DB-042255
NS00000626
EN300-20342
D77656
AH-034/32828041
Q27292660
Z104477824
4-Chlorobenzophenone, United States Pharmacopeia (USP) Reference Standard
205-160-7