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(4-Chlorophenyl)methanol

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Identification
Molecular formula
C7H7ClO
CAS number
873-76-7
IUPAC name
(4-chlorophenyl)methanol
State
State

(4-Chlorophenyl)methanol is typically a solid at room temperature.

Melting point (Celsius)
62.00
Melting point (Kelvin)
335.15
Boiling point (Celsius)
258.00
Boiling point (Kelvin)
531.15
General information
Molecular weight
142.58g/mol
Molar mass
142.5820g/mol
Density
1.2633g/cm3
Appearence

(4-Chlorophenyl)methanol appears as white to off-white crystalline solid. The crystalline structure may vary slightly depending on purity and form.

Comment on solubility

Solubility of (4-chlorophenyl)methanol

(4-chlorophenyl)methanol, also known as para-chlorobenzyl alcohol, showcases distinctive solubility properties that can be attributed to its molecular structure. As an aromatic compound with a hydroxyl group, it has both hydrophobic and hydrophilic characteristics, affecting its solubility in various solvents.

Solubility Characteristics:

  • Polar Solvents: (4-chlorophenyl)methanol is generally soluble in polar solvents such as water and alcohols due to the presence of its hydroxyl group, which can form hydrogen bonds.
  • Non-Polar Solvents: The aromatic ring contributes to some level of solubility in non-polar solvents, although to a lesser extent than in polar solvents.
  • Temperature Effect: Like many organic compounds, its solubility may increase with temperature, making it more soluble in warmer conditions.

In summary, the solubility of (4-chlorophenyl)methanol in various solvents can be summarized as:

  1. Highly soluble in water and polar solvents.
  2. Moderately soluble in non-polar solvents.
  3. Solubility increases with temperature.

As a compound of interest, understanding the solubility of (4-chlorophenyl)methanol is essential for its applications in organic synthesis and pharmaceuticals. "The relationship between solubility and molecular structure can often determine the utility of compounds in various chemical processes."

Interesting facts

Interesting Facts About (4-chlorophenyl)methanol

(4-chlorophenyl)methanol, commonly referred to in a more practical context as p-chlorobenzyl alcohol, is a fascinating compound with a range of applications and characteristics that pique the interest of both chemists and environmental scientists.

Chemical Structure and Properties

The compound features a benzene ring with a chlorine substituent in the para position, attached to a methanol group. This structure has implications on its reactivity and interaction with other substances:

  • Polarity: The presence of the hydroxyl group (-OH) contributes to its polar nature, affecting its solubility and reactivity.
  • Chlorine Effect: The chlorine atom acts as a strong electron-withdrawing group, which can influence its behavior in electrophilic substitution reactions.

Applications

This compound finds use in various fields, including:

  • Synthesis: It is utilized in the synthesis of pharmaceuticals and agrochemicals where chlorinated aromatic compounds are essential.
  • Biological Studies: Research indicates its potential as an antibacterial agent, making it a candidate in medicinal chemistry.

Environmental Impact

With the ongoing exploration of safer chemical alternatives, the environmental impact of (4-chlorophenyl)methanol has also come under scrutiny:

  • Toxicology: It has been studied for its toxicity to aquatic life, necessitating careful handling and disposal.
  • Regulations: Awareness of chlorinated compounds helps promote compliance with environmental regulations to minimize ecological risks.

Research and Future Prospects

In the realm of organic chemistry, compounds like (4-chlorophenyl)methanol open pathways for innovative research:

  • Researchers are investigating new synthetic routes that are more environmentally friendly.
  • The compound also poses opportunities for developing novel antibacterial agents amidst rising antibiotic resistance.

In summary, (4-chlorophenyl)methanol exemplifies the intersection of chemical structure, application, and ecological considerations, providing a rich area for both academic inquiry and practical application.

Synonyms
4-Chlorobenzyl alcohol
873-76-7
P-CHLOROBENZYL ALCOHOL
Benzenemethanol, 4-chloro-
4-Chlorobenzenemethanol
Benzyl alcohol, p-chloro-
4-Chlorobenzylic alcohol
CCRIS 5120
p-chlorotoluol
NSC 5286
EINECS 212-852-2
GF8BS53B6V
4-chlorophenylmethanol
AI3-20628
NSC-5286
DTXSID7073937
DTXCID8048579
Benzenemethanol, 4-chloro-(9CI)
(4-Chlorophenyl)methanol
4-Chlorobenzylalcohol
MFCD00004652
(4-chloro-phenyl)-methanol
CHEMBL1224554
UNII-GF8BS53B6V
p-chloro-benzylalcoho
p-chlorobenzyl-alcohol
4-chloro-benzyl alcohol
para-chlorobenzyl alcohol
(4-chlorophenyl) methanol
(4-chlorophenyl)-methanol
(4-Chlorophenyl)methanol #
SCHEMBL50385
4-Chlorobenzyl alcohol, 99%
1-chloro-4-hydroxymethylbenzene
NSC5286
CS-D1681
AC7505
BBL011936
BDBM50325563
STL163452
AKOS000119500
FC38176
PS-5314
BP-10435
SY001234
4-Chlorobenzyl alcohol, analytical standard
DB-076930
NS00039188
EN300-20398
A842116
AB-131/40228314
Q27279073
Z104478032
InChI=1/C7H7ClO/c8-7-3-1-6(5-9)2-4-7/h1-4,9H,5H
4JL