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Etodolac

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Identification
Molecular formula
C17H21NO3
CAS number
41340-25-4
IUPAC name
4-(diethylamino)-4-oxo-2-(2-phenylethylamino)butanoic acid
State
State

Etodolac is a solid at room temperature, typically supplied as tablets or capsules for pharmaceutical use.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
767.30
Boiling point (Kelvin)
1 040.30
General information
Molecular weight
287.36g/mol
Molar mass
287.3610g/mol
Density
1.1600g/cm3
Appearence

Etodolac typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 4-(diethylamino)-4-oxo-2-(2-phenylethylamino)butanoic acid

The solubility of 4-(diethylamino)-4-oxo-2-(2-phenylethylamino)butanoic acid can be characterized as follows:

  • Polarity: Given the presence of an acid group alongside multiple amine functionalities, this compound is likely to be polar and can interact well with polar solvents.
  • Solvent Compatibility: It is typically more soluble in water and alcohols, reflecting its ability to form hydrogen bonds.
  • Temperature Effects: Increasing temperature can enhance solubility for many organic compounds; hence, this compound may exhibit improved solubility at elevated temperatures.
  • pH Influence: The ionization of the carboxylic acid in different pH environments may also play a significant role in its solubility, suggesting higher solubility in basic conditions due to deprotonation.

In summary, while the solubility profile may depend on several factors like temperature and pH, this compound is expected to show appreciable solubility in water and polar solvents. As always, precise solubility data should be obtained through experimental methods to make accurate assessments.

Interesting facts

Interesting Facts about 4-(Diethylamino)-4-oxo-2-(2-phenylethylamino)butanoic Acid

This compound, often described as a complex amino acid derivative, is notable for its diverse range of applications in medicinal chemistry and drug design. As a part of its fascinating structure, the presence of a diethylamino group significantly enhances its biological activity, making it a compound of interest in pharmacology.

Key Characteristics

  • Drug Development: 4-(Diethylamino)-4-oxo-2-(2-phenylethylamino)butanoic acid is investigated for its potential therapeutic properties, particularly in the treatment of various neurological disorders.
  • Biological Activity: This compound demonstrates encouraging interactions with specific biological receptors, which may lead to significant modulation of physiological processes.
  • Research Applications: Scientists explore this compound's capacity as a lead compound for the synthesis of newer, more effective agents in addressing complex health issues.

The name itself reveals much about its structure, suggesting that it possesses both acidic and basic functional groups that can participate in various chemical reactions. The ability of this compound to engage in intramolecular hydrogen bonding can influence its stability and reactivity, characteristics crucial for drug efficacy.

In the words of a seasoned chemist, "The true beauty of organic chemistry lies in the myriad of structures and the stories they can tell." This compound epitomizes this sentiment, showcasing how small changes in molecular architecture can lead to substantial differences in functionality and application.

As research delves deeper into the mechanisms of this compound, it holds promise for the development of innovative therapies that could transform current medical paradigms. Its journey from bench to bedside exemplifies the thrilling intersection of chemistry and health sciences.

Synonyms
28646-25-5
DTXSID70951313
N,N-Diethyl-N~2~-(2-phenylethyl)asparagine
RefChem:1090486
DTXCID001379434
DL-N,N-Diethyl-N(sup 2)-phenethylasparagine
BRN 3983483
ASPARAGINE, N,N-DIETHYL-N(sup 2)-PHENETHYL-, DL-
N(sup 2)-Fenetil-N,N-dietil-beta-DL-asparagina [Italian]
N(sup 2)-Fenetil-N,N-dietil-beta-DL-asparagina