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N-(4-carboxyphenyl)-N-ethylsulfamide

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Identification
Molecular formula
C11H15NO4S
CAS number
3309-68-0
IUPAC name
4-(diethylsulfamoyl)benzoic acid
State
State

At room temperature, 4-(diethylsulfamoyl)benzoic acid is a solid. Its stability and structure make it remain in this solid state under normal conditions, making it useful for various chemical applications.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
429.60
Boiling point (Kelvin)
702.80
General information
Molecular weight
243.31g/mol
Molar mass
243.2900g/mol
Density
1.2736g/cm3
Appearence

4-(diethylsulfamoyl)benzoic acid appears as a white crystalline solid. This compound is typically handled in powdered form and is known for its relatively stable nature in a controlled environment.

Comment on solubility

Solubility of 4-(diethylsulfamoyl)benzoic acid

4-(diethylsulfamoyl)benzoic acid, a compound with potential pharmaceutical applications, exhibits intriguing solubility characteristics. In general, the solubility of this compound can be affected by various factors, including:

  • Polarity: The sulfonamide functional group contributes to the overall polarity, which may enhance its solubility in polar solvents like water.
  • pH Levels: As a benzoic acid derivative, its solubility may vary significantly with changes in pH due to protonation and deprotonation processes.
  • Temperature: Higher temperatures often lead to increased molecular motion, which can enhance solubility.
  • Interaction with Solvents: Its ability to form hydrogen bonds can facilitate its dissolution in various organic solvents.

In general, while 4-(diethylsulfamoyl)benzoic acid may show solubility in polar solvents, it might be less soluble in nonpolar solvents. It’s important to consider these factors for effective use in applications such as drug formulation. As always, conducting specific solubility tests can provide concrete data for practical applications.

Interesting facts

Interesting Facts about 4-(diethylsulfamoyl)benzoic acid

4-(diethylsulfamoyl)benzoic acid is a fascinating compound that plays a significant role in the field of medicinal chemistry. Here are some noteworthy aspects about this compound:

  • Pharmaceutical Relevance: This compound is often studied for its potential applications as a drug molecule. Its structural properties may contribute to biological activity, making it a valuable candidate for the development of new medications.
  • Sulfonamide Connection: The presence of the sulfonamide group in this compound links it to a class of drugs known for their antibacterial properties. This connection stimulates research into its effectiveness against various pathogens.
  • Acidic Properties: As a benzoic acid derivative, it possesses acidic characteristics that can be tuned for various chemical reactions, making it an interesting subject for synthetic organic chemists.
  • Medicinal Chemistry: Researchers have utilized this compound as a structural template for designing inhibitors or modulators that target specific enzymes related to various diseases.
  • Interdisciplinary Applications: The compound serves as a bridge between multiple scientific disciplines, including organic chemistry, pharmacology, and biochemistry. This makes it a point of interest in ongoing collaborative research projects.

In summary, 4-(diethylsulfamoyl)benzoic acid is not just a chemical formula; it represents a blend of chemistry and medicine that continues to inspire innovations and deepen our understanding of drug development and design. As researchers delve into its properties and potential uses, this compound stands at the forefront of science, illustrating how even small modifications to molecular structures can lead to significant advancements in healthcare.

Synonyms
Etebenecid
Ethebenecid
Ethebenecide
Urelim
4-[(Diethylamino)sulfonyl]benzoic acid
Etebenecidum
Etebenecida
Etebenecide
Etebenecid [INN]
p-(Diethylsulfamoyl)benzoic acid
p-Diethylsulfamoylbenzoic acid
N,N-Diethyl-p-sulfamoylbenzoic acid
p-Carboxy-N,N-diethylbenzenesulfonamide
4-((Diethylamino)sulfonyl)benzoic acid
4-Carboxy-N,N-diethylbenzenesulfonamide
Etebenecide [INN-French]
Etebenecidum [INN-Latin]
Etebenecida [INN-Spanish]
BENZOIC ACID, p-(DIETHYLSULFAMOYL)-
NSC 49467
Etebenecid [INN:BAN]
Benzoic acid, 4-[(diethylamino)sulfonyl]-
EINECS 214-925-4
NSC-49467
BRN 2812421
DTXSID7023011
Benzoic acid, 4-((diethylamino)sulfonyl)-
UNII-4413I5098G
ETHEBENECID [MI]
ETEBENECID [WHO-DD]
p-Diethylsulfamylbenzoic acid
DTXCID003011
4413I5098G
4-11-00-00691 (Beilstein Handbook Reference)
Etebenecide (INN-French)
Etebenecidum (INN-Latin)
Etebenecida (INN-Spanish)
Benzoic acid, 4-((diethylamino)sulfonyl)-(9CI)
214-925-4
uacoqeqobaqrdq-uhfffaoysa-n
1213-06-5
4-(diethylsulfamoyl)benzoic acid
4-Diethylsulfamoyl-benzoic acid
Etamid
4-(N,N-diethylsulfamoyl)benzoic acid
NCGC00160437-01
SMR000685799
CAS-1213-06-5
MFCD00020373
N,N-DIETHYL-4-SULFAMOYLBENZOIC ACID
Oprea1_182805
MLS000881133
MLS000881184
IFLab1_005538
SCHEMBL1643610
CHEMBL1705586
CHEBI:135060
HMS1427L16
HMS2992H15
ALBB-006583
HY-B0939
NSC49467
Tox21_111810
STK501236
AKOS000112051
Tox21_111810_1
AT24937
CCG-213930
IDI1_010941
NCGC00160437-03
DA-63290
LS-02333
NS00023959
EN300-00397
AB00865141_06
AQ-390/42869863
SR-01000833862
SR-01000833862-3
BRD-K24443618-001-08-6
BRD-K24443618-001-10-2
Q27258685
Z53036662
F1386-0327