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Atenolol

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Identification
Molecular formula
C14H22N2O3
CAS number
14132-53-5
IUPAC name
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide;phosphoric acid
State
State

At room temperature, Atenolol is in a solid state. It is typically manufactured and used in the form of tablets or capsules, incorporated with other inactive substances for medical usage.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
266.34g/mol
Molar mass
266.3360g/mol
Density
1.2000g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. Due to its crystalline structure, light reflecting off these surfaces gives it a slightly shiny appearance. There is no significant odor associated with its solid form.

Comment on solubility

Solubility of 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide; phosphoric acid

The solubility of the compound 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide; phosphoric acid is influenced by various factors due to its complex structure. Here are some key points to consider:

  • Polarity: The presence of the phosphoric acid component typically increases the polarity of the compound, which can enhance its solubility in polar solvents such as water.
  • Hydrogen bonding: The ability of the amide and phosphoric acid groups to engage in hydrogen bonding can further facilitate solubility in aqueous environments.
  • Solvent effects: In addition to water, the compound may exhibit variable solubility in organic solvents depending on their polarity. For instance, solvents like dimethyl sulfoxide (DMSO) or ethanol could potentially dissolve this compound due to their polar characteristics.
  • Temperature dependence: Like many compounds, the solubility of this compound may increase with temperature, allowing for greater dissolution in hot solvents compared to cold.

In summary, understanding the solubility of 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide; phosphoric acid is crucial for its effective application in various chemical contexts. Factors such as polarity, hydrogen bonding capabilities, and solvent choice play pivotal roles in determining how well this compound can be dissolved.

Interesting facts

Interesting Facts about 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide; Phosphoric Acid

This compound is a fascinating example of the intricate world of organic chemistry, blending amide functionality with the role of phosphoric acid in industrial and pharmaceutical applications. Here are some captivating insights:

  • Versatile Applications: Compounds like this are often investigated for their potential use as intermediates in the synthesis of various pharmaceuticals. The presence of the diisopropylamino group suggests it could play a significant role in developing drugs designed to target specific receptors in the body.
  • Unique Structure: The structure incorporates both a phenyl and a pyridine ring, which are known for their diverse chemical properties. This duality enhances the compound's reactivity, making it an interesting candidate for further study in organic synthesis.
  • Phosphoric Acid Connection: By including phosphoric acid, this compound may participate in a variety of chemical reactions, especially in creating phosphoramidates, which have notable uses in biochemistry and agriculture.
  • Symmetry and Chirality: The presence of branched substituents like diisopropyl groups introduces potential for chirality within the molecule. This characteristic is essential in medicinal chemistry, where the biological activity of compounds often hinges on their chiral configuration.
  • Scientific Inquiry: As a chemistry student or researcher, understanding such compounds opens doors to exploring drug design, molecular recognition, and the design of new materials. This compound could lead to a deeper appreciation of how molecular structure influences function.

In conclusion, 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide; phosphoric acid exemplifies the complexity and beauty of organic compound design, making it a subject of dynamic research and inquiry in the fields of chemistry and pharmacology.

Synonyms
DISOPYRAMIDE PHOSPHATE
22059-60-5
Norpace
Rythmodan
Norpace Cr
Dirythmin sa
Diso-duriles
SC-7031 PHOSPHATE
NSC-756744
CHEBI:4658
N6BOM1935W
SC-13957
DTXSID30944685
2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium phosphate
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide;phosphoric acid
Dirythmin
Rythmodan ret
Dirythmin-sa
Isomide cr
RefChem:56639
Disopyramide Phosphate (1:1)
DTXCID301373023
SC13957
alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide Phosphate(1:1)
DISOPYRAMIDE PHOSPHATE SALT
DisopyramidePhosphate
SC 7031 phosphate
EINECS 244-756-1
SC 7031 (phosphate)
22059-60-5 (phosphate)
MFCD00069254
Disopyramid phosphate
4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate
C21H32N3O5P
SR-01000003039
Disopyramide phosphate; (2RS)-4-[bis(1-methylethyl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide dihydrogen phosphate
Norpace (TN)
SC 13957
Disopyramide (phosphate)
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid
UNII-N6BOM1935W
SCHEMBL41810
MLS000028431
SPECTRUM1500261
orb1705063
CHEMBL1201020
HMS501I11
CGDDQFMPGMYYQP-UHFFFAOYSA-N
Disopyramide phosphate (JAN/USP)
HMS1920I14
HMS2094K15
HMS2234B16
HMS3259J21
HMS3261C04
HMS3369L05
HMS3652M20
HMS3885J07
HMS5082E20
HMS5083M09
Pharmakon1600-01500261
DISOPYRAMIDE PHOSPHATE [MI]
XAA05960
DISOPYRAMIDE PHOSPHATE [JAN]
Tox21_500411
CCG-40209
DISOPYRAMIDE PHOSPHATE [USAN]
HY-12533A
NSC756744
DISOPYRAMIDE PHOSPHATE [VANDF]
AKOS040744844
alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate
DISOPYRAMIDE PHOSPHATE [MART.]
DISOPYRAMIDE PHOSPHATE [USP-RS]
DISOPYRAMIDE PHOSPHATE [WHO-DD]
LP00411
NC00683
NSC 756744
(+-)-alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-, phosphate
alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1)
NCGC00093836-01
NCGC00093836-02
NCGC00093836-03
NCGC00093836-04
NCGC00261096-01
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, (+-)-, phosphate (1:1)
SMR000058438
DB-045779
DISOPYRAMIDE PHOSPHATE [ORANGE BOOK]
DISOPYRAMIDE PHOSPHATE [EP MONOGRAPH]
Disopyramide phosphate [USAN:USP:BAN:JAN]
EU-0100411
S4143
SW196836-3
SW196836-4
DISOPYRAMIDE PHOSPHATE [USP MONOGRAPH]
C07740
D 6035
D00637
H40410
SR-01000003039-2
SR-01000003039-6
Q27106430
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide,phosphoric acid
4-DIISOPROPYLAMINO-2-PHENYL-2-(2-PYRIDYL)BUTYRAMIDE PHOSPHATE
Disopyramide phosphate, European Pharmacopoeia (EP) Reference Standard
Disopyramide phosphate, United States Pharmacopeia (USP) Reference Standard
(+/-)-.ALPHA.-(2-(DIISOPROPYLAMINO)ETHYL)-.ALPHA.-PHENYL-2-PYRIDINEACETAMIDE PHOSPHATE (1:1)
2-PYRIDINEACETAMIDE, .ALPHA.-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-.ALPHA.-PHENYL-, (+/-)-, PHOSPHATE (1:1)
79190-73-1