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4-Dimethoxyphosphoryl-N-methylmorpholine

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Identification
Molecular formula
C6H14NO4P
CAS number
824-11-3
IUPAC name
4-dimethoxyphosphorylmorpholine
State
State

At room temperature, 4-Dimethoxyphosphoryl-N-methylmorpholine is typically found as a liquid due to its relatively low melting point but can be observed as a solid under cooler conditions.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
197.16g/mol
Molar mass
197.1660g/mol
Density
1.2040g/cm3
Appearence

4-Dimethoxyphosphoryl-N-methylmorpholine appears as a colorless to pale yellow liquid. It may have a slight amine-like odor due to the morpholine structure in its composition.

Comment on solubility

Solubility of 4-dimethoxyphosphorylmorpholine

4-dimethoxyphosphorylmorpholine, with the chemical formula C7H16N2O4P, exhibits interesting solubility characteristics that are worth noting:

  • Polar Nature: The presence of the phosphoryl group contributes to its polar nature, which can enhance solubility in polar solvents.
  • Water Solubility: It is expected to have good solubility in water due to hydrogen bonding capabilities stemming from its morpholine structure and -OCH3 groups.
  • Organic Solvents: Additionally, 4-dimethoxyphosphorylmorpholine may also show solubility in organic solvents such as methanol and ethanol, where it can interact favorably.
  • Temperature Dependency: Like many chemical compounds, solubility may vary with temperature; generally, higher temperatures can increase solubility.

In conclusion, the compound's solubility profile illustrates its potential applications in various chemical reactions and processes. As a general rule, compounds with polar functional groups tend to have enhanced solubility in polar solvents, making 4-dimethoxyphosphorylmorpholine a prime candidate for studies involving solvent-based chemistry.

Interesting facts

Interesting Facts About 4-Dimethoxyphosphorylmorpholine

4-Dimethoxyphosphorylmorpholine is a fascinating chemical compound that holds significant interest in the field of medicinal chemistry and drug development. Here are some intriguing facts about this compound:

  • Phosphorylation potential: The presence of the dimethoxyphosphoryl group makes this compound a prime candidate for phosphorylation reactions, which are vital in biological processes and drug mechanisms.
  • Versatile structure: The morpholine ring structure imparts unique properties to the compound, enabling it to participate in various chemical reactions and interactions.
  • Medicinal applications: Compounds containing phosphorylimidine structures, such as 4-dimethoxyphosphorylmorpholine, have been investigated for their potential as anticancer agents and antiviral therapies.
  • Biological relevance: Morpholine derivatives are known for their ability to act as substrates for various enzymes, making them important in the study of biochemical pathways.
  • Synthetic interest: The synthesis of this compound often involves advanced methods of organic synthesis, showcasing innovative techniques that can inspire future research in organic chemistry.

As noted by one researcher, "The potential applications of phosphorylated morpholines open new avenues in drug design and delivery, making them indispensable in modern chemistry."

In summary, 4-dimethoxyphosphorylmorpholine represents a convergence of structural complexity and functional versatility, making it an intriguing subject for ongoing research and exploration in the chemistry community.

Synonyms
597-25-1
DIMETHYL MORPHOLINOPHOSPHORAMIDATE
Dimethyl morpholinophosphonate
Dimethyl 4-morpholinylphosphonate
NCI-C54740
CCRIS 1352
Dimethylmorpholinophosphoramidate
HC 1717
Morpholinophosphonic acid dimethyl ester
HSDB 4195
UNII-D1B75YF8F1
Phosphonic acid, 4-morpholinyl-, dimethyl ester
BRN 0141995
D1B75YF8F1
Phosphonic acid, morpholino-, dimethyl ester
Dimethylmorpholinophosphonate
DTXSID5020495
4-27-00-00629 (Beilstein Handbook Reference)
DIMETHYL MORPHOLINOPHOSPHORAMIDATE [HSDB]
PHOSPHONIC ACID, P-4-MORPHOLINYL-, DIMETHYL ESTER
DM-MP
4-morpholinylphosphonic acid dimethyl ester
DTXCID70495
Dimethyl 4morpholinylphosphonate
Phosphonic acid, morpholino, dimethyl ester
Phosphonic acid, 4morpholinyl, dimethyl ester
Phosphonic acid, 4morpholinyl, dimethyl ester (9CI)
Phosphonic acid, 4-morpholinyl-, dimethyl ester (9CI)
bzxuqidkdggypb-uhfffaoysa-n
dimethyl (morpholin-4-yl)phosphonate
4-dimethoxyphosphorylmorpholine
Dimethyl morpholinophosphoramidate.
dimethyl morpholin-4-ylphosphonate
MFCD00514647
SCHEMBL13022048
dimethyl(morpholin-4-yl)phosphonate
AKOS006272524
SS-4559
CS-0454136
NS00120597
Q27275969