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Anfepramone

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Identification
Molecular formula
C18H31NO2
CAS number
90-84-6
IUPAC name
[4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate
State
State

At room temperature, Anfepramone is generally in a solid state, available as a powder or in tablet form. As a hydrochloride salt, it is more stable and suitable for pharmaceutical preparation.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
334.40
Boiling point (Kelvin)
607.55
General information
Molecular weight
263.46g/mol
Molar mass
263.3810g/mol
Density
0.9647g/cm3
Appearence

Anfepramone typically appears as a white to off-white crystalline powder. It is often manufactured in the form of tablets intended for oral use.

Comment on solubility

Solubility of [4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate

The solubility of the compound [4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate can be quite complex due to its intricate structure which includes both hydrophobic and hydrophilic features. Understanding solubility requires considering several factors:

  • Polarity: The presence of the acetate group typically contributes to the hydrophilic character of the molecule, potentially increasing solubility in polar solvents like water. However, the dimethylamino and diphenyl groups may impart hydrophobic characteristics, making the overall solubility more variable.
  • Solvent Effects: This compound may display greater solubility in organic solvents such as ethanol, methanol, or dichloromethane, compared to water. Alcohols, in particular, could facilitate better solvation due to their ability to form hydrogen bonds.
  • Temperature: As with many organic compounds, an increase in temperature often enhances solubility. This manifests due to increased molecular motion and interaction with solvent molecules.

In summary, while [4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate might exhibit some solubility in polar solvents, it is likely to show much greater solubility in nonpolar or weakly polar organic solvents. Testing for solubility in various environments will provide a clearer picture of its behavior, making empirical analysis essential. As the saying goes, "The solvent makes the solute!"

Interesting facts

Interesting Facts about [4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate

This compound is a fascinating member of the category of chemical compounds known as acetates. It possesses unique properties and applications that make it a subject of interest in both academic and industrial contexts. Here are some noteworthy points:

  • Structure and Functionality: The compound features a complex structure that includes a dimethylamino group and a diphenyl substituent. Its diverse functional groups contribute to its reactivity and potential applications in various chemical reactions.
  • Pharmaceutical Applications: Compounds with similar structural motifs are often explored for their potential therapeutic effects. They may exhibit properties that can be exploited in drug development, particularly in targeting neurological conditions.
  • Synthetic Utility: The synthesis of [4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate could serve as a model for studying reaction kinetics as well as sterics and electronics in organic reactions, providing valuable information to chemists.
  • Research Interests: The compound is of notable interest in the field of medicinal chemistry, where scientists are constantly seeking to modify existing structures to enhance efficacy and reduce side effects.
  • Novelty and Innovation: Given the intricate design of its molecular structure, chemists may investigate this compound in the context of new materials science, with potential applications in nanotechnology or polymers.

In conclusion, the compound [4-(dimethylamino)-1-ethyl-2,2-diphenyl-pentyl] acetate stands as an intriguing subject for the exploration of its various properties and potentials. As emphasized by many in the field, “The key to discovery lies in understanding the molecular intricacies of compounds and their interactions.”

Synonyms
Methadyl acetate
Acetylmethadol
Acemethadone
race-Acetylmethadol
Acetilmetadol [INN-Spanish]
Acetylmethadolum [INN-Latin]
Methadyl acetate [USAN]
Acetylmethadol (INN)
Acetylmethadol [INN]
3-Acetoxy-6-dimethylamino-4,4-diphenylheptane
Methadyl acetate (USAN)
UNII-L59OC40KWJ
EINECS 208-103-4
6-(Dimethylamino)-4,4-diphenyl-3-heptanol acetate (ester)
1-Ethyl-4-dimethylamino-2,2-diphenylpentylacetat
ACSCN-9601
IDS-NA-004
(R,S)-4-Dimethylamino-1-ethyl-2,2-diphenylpentyl acetat
NIH-2953
METHADYL ACETATE [MI]
Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, acetate (ester)
DTXSID2023274
Acetilmetadol (INN-Spanish)
Acetylmethadolum (INN-Latin)
O-ACETYL-6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEPTANOL
BENZENEETHANOL, .BETA.-(2-(DIMETHYLAMINO)PROPYL)-.ALPHA.-ETHYL-.BETA.-PHENYL-, ACETATE (ESTER)
6-(Dimethylamino)-4,4-Diphenyl-3-Heptanol Acetate
DTXCID403274
6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate
(3r,6r)-3-acetoxy-6-dimethylamino-4,4-diphenylheptane
Acetilmetadol
509-74-0
[6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate
L59OC40KWJ
CHEMBL170179
Acetylmethadolum
Levomethadyl
DEA No. 9601
SCHEMBL119911
4-(Dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate
CHEBI:135491
BDBM50027391
DB01433
NS00067937
D04973
L000758
Q4673310
Acetic acid 4-dimethylamino-1-ethyl-2,2-diphenyl-pentyl ester
Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-diphenyl-pentyl ester
Benzeneethanol, .beta.-((2S)-2-(dimethylamino)propyl)-.alpha.-ethyl-.beta.-phenyl-, acetate (ester), (.alpha.S)-
Benzeneethanol, .beta.-[2-(dimethylamino)propyl]-.alpha.-ethyl-.beta.-phenyl-, acetate (ester), [S-(R*,R*)]-