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Tramadol

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Identification
Molecular formula
C16H25NO2
CAS number
27203-92-5
IUPAC name
4-(dimethylamino)-1-hydroxy-1,1-diphenyl-butan-2-one
State
State

Tramadol at room temperature typically exists in a solid crystalline state, in the form of its hydrochloride salt. It is widely available in tablet or capsule form for oral administration.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
401.00
Boiling point (Kelvin)
674.15
General information
Molecular weight
263.38g/mol
Molar mass
263.3840g/mol
Density
1.1600g/cm3
Appearence

Tramadol is a white to off-white crystalline powder. It is highly soluble in water and methanol but exhibits limited solubility in other organic solvents. The compound is typically supplied in its hydrochloride salt due to enhanced solubility and stability.

Comment on solubility

Solubility of 4-(dimethylamino)-1-hydroxy-1,1-diphenyl-butan-2-one

The solubility of 4-(dimethylamino)-1-hydroxy-1,1-diphenyl-butan-2-one can be characterized by its unique chemical structure. This compound, known for its interesting functional groups, exhibits varying solubility in different solvents. Here are some key points regarding its solubility:

  • Polar Solvents: Due to the presence of the hydroxy group, this compound tends to have increased solubility in polar solvents such as water and alcohols.
  • Non-Polar Solvents: It can also dissolve in non-polar solvents, but to a lesser extent, primarily because of its large hydrophobic diphenyl groups.
  • pH Dependence: The solubility may change with pH variations, influenced by the protonation of the dimethylamino group in acidic conditions.

In summary, the solubility profile of this compound is a function of both its molecular characteristics and the environmental conditions. As this compound is utilized in various chemical applications, understanding its solubility is crucial for optimizing its effectiveness in solutions and formulations.

Interesting facts

Interesting Facts about 4-(Dimethylamino)-1-hydroxy-1,1-diphenyl-butan-2-one

This fascinating compound, commonly known in the field of organic chemistry, exhibits a variety of intriguing characteristics and applications due to its unique structure and functional groups. Here are some key insights into this compound:

  • Dual Functional Groups: The presence of both a hydroxy group and a dimethylamino group makes this compound particularly versatile, allowing it to participate in various chemical reactions and interactions.
  • Importance in Photochemistry: Compounds with similar structural motifs are often studied for their photochemical properties, making them useful in applications such as dyes or luminescent materials.
  • Biological Activity: Many compounds that contain dimethylamino groups have notable biological activities, influencing their use in pharmaceuticals. Understanding their mechanism can lead to advances in drug development.
  • Synthetic Pathways: The synthesis of this compound can involve diverse approaches, often requiring careful control of reaction conditions to achieve optimal yields and purity.
  • Analytical Techniques: Its unique structure provides ample opportunities for analysis using spectroscopic techniques such as NMR, IR, and UV-Vis, crucial for determining structural characteristics and verifying purity.

In summary, 4-(Dimethylamino)-1-hydroxy-1,1-diphenyl-butan-2-one encompasses a rich chemistry that not only highlights the beauty of molecular structure but also paves the way for numerous practical applications in both academic research and industrial settings. As scientists continue to explore its potentials, we can anticipate exciting advancements driven by such compounds.

Synonyms
BRN 2813773
2-BUTANONE, 4-DIMETHYLAMINO-1,1-DIPHENYL-1-HYDROXY-
13960-24-2
4-Dimethylamino-1,11-diphenyl-1-hydroxy-2-butazone
DTXSID00161120
DTXCID1083611