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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanamide
State
State

At room temperature, lidocaine exists as a solid. It is often manipulated and administered in solution form for ease of use in various medical applications.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is typically a white to slightly yellow crystalline powder. It is often encountered in its hydrochloride salt form, which remains odorless. The compound is soluble in water, often lending itself to aqueous solutions for medical use.

Comment on solubility

Solubility of 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanamide

The solubility of 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanamide, often referred to as a complex organic compound, can be influenced by various factors. Understanding its solubility profile is essential for applications such as drug formulation and chemical synthesis. Here are some key points regarding its solubility:

  • Solvent Dependency: This compound is likely to exhibit different solubility characteristics in a range of solvents. It may be more soluble in polar solvents due to the presence of the amino groups that can engage in hydrogen bonding.
  • Impact of Temperature: Generally, solubility can increase with temperature. Therefore, it is advisable to test varied temperatures to determine how the solubility changes.
  • pH Levels: The solubility may also be affected by the pH of the solution. Since it contains basic amine groups, changes in pH can significantly impact its ionization and, consequently, its solubility.

In conclusion, the solubility of this compound is multifaceted and necessitates thorough investigation under specific conditions to fully understand its capabilities and behavior in different environments. It is crucial for chemists to conduct empirical testing in their solubility assessments, ensuring accurate results for practical applications.

Interesting facts

Interesting Facts about 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanamide

This compound, known for its complex structure, is of great interest in the field of medicinal chemistry due to its unique properties and potential applications. Here are some fascinating aspects of this compound:

  • Structural Complexity: The compound contains multiple functional groups, making it an intriguing subject for the study of structure-activity relationships (SAR) in drug design.
  • Pharmacological Activity: It belongs to a class of compounds that can exhibit significant pharmacological properties, potentially influencing neurotransmitter systems, which is essential in the development of therapies for neurological disorders.
  • Tertiary Amines: The presence of dimethylamino groups can enhance the lipophilicity of the molecule, influencing its ability to cross biological membranes and interact with receptors in the central nervous system.
  • Research Potential: Compounds with similar structures are often studied for their roles as analgesics or their ability to modulate pain pathways, contributing to the understanding of pain management strategies.
  • Multifunctionality: The combination of amide and amine functionalities opens up avenues for further chemical modifications, allowing chemists to explore more derivatives with potentially enhanced efficacy.

As one delves deeper into its synthesis and reactivity, this compound stands as a testament to the intricacies of organic chemistry and the endless possibilities that arise from simple variations in molecular structure. It highlights the pivotal role chemists play in shaping future pharmaceutical innovations.

Synonyms
BRN 2812448
3120-59-0
BUTYRAMIDE, 4-(DIMETHYLAMINO)-2-(2-(DIMETHYLAMINO)ETHYL)-2-PHENYL-
alpha,alpha-Bis(2-dimethylaminoethyl)phenylacetamide
DTXSID50185134
DTXCID60107625
4-14-00-01753 (beilstein handbook reference)