Skip to main content

Lobeline

ADVERTISEMENT
Identification
Molecular formula
C22H27N3O
CAS number
90-69-7
IUPAC name
4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanenitrile
State
State

At room temperature, lobeline is typically found in a solid state as a crystalline or powdery substance. It is stable under standard conditions but should be stored in a dry, cool environment to maintain its stability over time.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
359.00
Boiling point (Kelvin)
632.15
General information
Molecular weight
264.40g/mol
Molar mass
264.4030g/mol
Density
1.0150g/cm3
Appearence

Lobeline is a white crystalline solid when pure. It may also be found as a colorless or white powder. Industrial or synthetic samples may have variable coloration due to impurities. It is usually odorless or has a very faint characteristic odor.

Comment on solubility

Solubility of 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanenitrile

When assessing the solubility of 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanenitrile, several factors come into play, given its complex molecular structure. Here are some important aspects to consider:

  • Polarity: The presence of multiple dimethylamino groups tends to increase the polarity of the compound, which may lead to better solubility in polar solvents.
  • Hydrophobic Character: The phenyl group contributes to hydrophobic characteristics, which could reduce solubility in water.
  • Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO) than in water.

As a result, it is reasonable to conclude that:

  1. The compound exhibits variable solubility depending on the solvent used.
  2. It is expected to be soluble in common organic solvents.
  3. Its solubility in aqueous solutions might be limited due to the combination of hydrophobic and polar features.

In summary, while 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanenitrile has the potential for solubility in polar solvents, its overall solubility profile will fluctuate in accordance with the solvent environment.

Interesting facts

Interesting Facts about 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanenitrile

This intriguing compound, often referred to within chemical circles, showcases the fascinating interplay between molecular structure and biological activity. Here are some key insights:

  • Complex Structure: The compound features a multi-substituted benzene ring and several dimethylamino groups, suggesting potential interactions with various biological targets, particularly in the realm of medicinal chemistry.
  • Pharmacological Potential: Compounds with dimethylamino groups are known to enhance solubility and bioavailability. This characteristic may facilitate the exploration of this compound in drug development, especially in treating central nervous system disorders.
  • Structure-Activity Relationship (SAR): The presence of multiple nitrogen atoms can influence the compound's activity profile significantly. Studying SAR can lead to the design of derivatives optimized for specific therapeutic applications.
  • Research Interest: Scientists are increasingly interested in the biochemical pathways influenced by such compounds. This can spark inquiries into their impact on neurotransmitter systems, potentially leading to innovative treatments.
  • Application in Synthesis: The complexity of this molecule makes it a valuable target for synthetic chemists looking to develop novel methodologies for constructing intricate organic molecules.

Overall, 4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenyl-butanenitrile is not just a compound of academic interest; it holds the promise of contributing significantly to the fields of medicinal chemistry and pharmacology. As renowned chemist Robert H. Grubbs once said, "In chemistry, each new molecule represents a potential avenue for scientific innovation."

Synonyms
2809-47-4
BUTYRONITRILE, 4-(DIMETHYLAMINO)-2-(2-(DIMETHYLAMINO)ETHYL)-2-PHENYL-
BRN 2811962
DTXSID90182364
4-(Dimethylamino)-2-(2-(dimethylamino)ethyl)-2-phenylbutyronitrile
DTXCID00104855
4-14-00-01753 (beilstein handbook reference)
4-(dimethylamino)-2-[2-(dimethylamino)ethyl]-2-phenylbutanenitrile