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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[4-(dimethylamino)-2-[[(3R,4S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyl-tetrahydropyran-3-yl] propanoate
State
State

At room temperature, erythromycin is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
426.00
Boiling point (Kelvin)
699.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2000g/cm3
Appearence

Erythromycin is typically a white to off-white crystalline powder. It may have a faint odor and is known for its bitter taste.

Comment on solubility

Solubility of the Compound

The solubility of the compound with the name 4-(dimethylamino)-2-[[(3R,4S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyl-tetrahydropyran-3-yl] propanoate, characterized by its complex structure, can be influenced by various factors.

Key Factors Affecting Solubility:

  • Polarity: The presence of hydroxyl (-OH) groups generally enhances solubility in polar solvents, while larger hydrophobic regions may hinder it.
  • Hydrogen Bonding: The capacity for hydrogen bonding due to hydroxyl groups can significantly increase solubility in water.
  • pH of the Solution: Changes in pH can affect the ionization of functional groups, thus altering solubility.
  • Temperature: Typically, increased temperature can lead to increased solubility for most solids.

In general, it's expected that compounds similar to this one—those containing multiple oxygen functionalities—exhibit moderate to high solubility in water and other polar solvents. However, the exact solubility must be empirically determined, as theoretical predictions can often fall short in complex molecules.

As noted in the literature, "The solubility of a compound can often dictate its bioavailability and therapeutic efficacy," highlighting the importance of understanding solubility in chemical applications.

Interesting facts

Interesting Facts about 4-(Dimethylamino)-2-[[(3R,4S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyl-tetrahydropyran-3-yl propanoate

This compound is a fascinating example of complex organic chemistry, showcasing the intricate nature of chemical synthesis and the rich diversity of biological activity that can arise from tailored modifications of molecular structures.

Key Characteristics:

  • Structural Complexity: The compound features multiple hydroxyl groups and a long hydrocarbon chain, creating a sophisticated molecular framework that can influence its reactivity and interactions.
  • Dimethylamino Group: The presence of the dimethylamino moiety suggests potential for unique electrophilic characteristics, which can be crucial in biochemical pathways.
  • Tetrahydropyran Rings: These structures are notable for their ability to adopt several conformations, affecting how the compound interacts with biological targets.

Applications:

Due to its complexity, this compound may be of interest in various fields:

  • Medicinal Chemistry: Compounds with similar structures have shown promise in drug development, particularly as candidates for treatments against diseases such as cancer or bacterial infections.
  • Biological Research: Understanding how such compounds interact with biological systems can lend insight into metabolic pathways and enzyme functions.

Quote:

As noted by a prominent chemist, "The beauty of organic chemistry lies not only in its structures but also in the innovative ways these structures can modify biological reality."

This compound exemplifies that notion; its intricate design may unlock new avenues in both pharmaceuticals and materials science, showcasing the power of chemical synthesis in creating molecules with potential therapeutic applications.