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Verapamil

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Identification
Molecular formula
C27H38N2O4
CAS number
52-53-9
IUPAC name
4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanenitrile
State
State

At room temperature, verapamil hydrochloride is typically in a solid-state.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
312.10
Boiling point (Kelvin)
585.25
General information
Molecular weight
454.60g/mol
Molar mass
454.6010g/mol
Density
1.1080g/cm3
Appearence

Verapamil hydrochloride appears as a white or slightly yellow crystalline powder. It is odorless, or practically odorless, with a bitter taste.

Comment on solubility

Solubility of 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanenitrile

The solubility of 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanenitrile presents an intriguing aspect for study due to its unique chemical structure. Understanding its solubility is crucial for both practical applications and theoretical exploration. Here are some key points to consider:

  • Solvent Interaction: The presence of the dimethylamino group suggests potential polar characteristics, which may lead to reasonable solubility in polar solvents.
  • Hydrophobic Effects: The 1-naphthyl moiety introduces significant hydrophobic character, potentially decreasing solubility in water but enhancing it in organic solvents.
  • Temperature Dependencies: Solubility can vary significantly with temperature; typically, higher temperatures increase the solubility of organic compounds.

In summary, while empirical data would provide precise solubility values, the balance between polar and nonpolar characteristics in 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanenitrile indicates that:

  • It may be soluble in polar organic solvents such as methanol or ethanol.
  • It is likely insoluble or only sparingly soluble in water due to its hydrophobic elements.

Thus, experimental determination is essential to confirm these predictions and to better understand its solubility behavior in various mediums.

Interesting facts

Interesting Facts about 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanenitrile

This compound, known for its unique structure and properties, belongs to the family of organic nitriles. It boasts an intriguing array of characteristics, making it a subject of interest in various fields such as pharmacology and materials science.

Chemical Structure

The compound features:

  • A dimethylamino group, providing it with significant electronic properties that influence its reactivity.
  • An ethyl substituent that adds to its structural complexity and potential interactions.
  • A naphthyl ring, which enhances its hydrophobicity and can impact its solubility in organic solvents.
  • The presence of a butanenitrile moiety, which introduces a polar functional group, making the compound capable of unique chemical behavior.

Applications

This compound has garnered attention for its potential applications:

  • Drug Development: With its specific structure, it may be used as a lead compound in the development of pharmaceuticals.
  • Organic Synthesis: It can serve as an intermediate or building block in the synthesis of other complex organic molecules.
  • Research: Used in the study of various chemical reactions and mechanisms related to nitriles.

Significance of Nitriles

Nitriles like this compound are significant in the chemical world for several reasons:

  • They often exhibit versatile reactivity, allowing for various transformations.
  • Their presence in biological systems sometimes relates to signaling pathways, making them important in biochemistry.
  • Many nitriles are known to have distinct effects in pharmaceutical applications, acting as precursors or active agents.

In conclusion, 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanenitrile is a fascinating compound with diverse applications and a complex structure, highlighting the beautiful intricacies of organic chemistry. As a science student or researcher, exploring its potential and properties is both challenging and rewarding!

Synonyms
1224-44-8
4-(dimethylamino)-2-ethyl-2-naphthalen-1-ylbutanenitrile
alpha-(2-(Dimethylamino)ethyl)-alpha-ethyl-1-naphthaleneacetonitrile
alpha-[2-(Dimethylamino)ethyl]-alpha-ethyl-1-naphthaleneacetonitrile
BRN 2142563
1-NAPHTHALENEACETONITRILE, alpha-(2-(DIMETHYLAMINO)ETHYL)-alpha-ETHYL-
DTXSID20924153
4-(dimethylamino)-2-ethyl-2-(naphthalen-1-yl)butanenitrile