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Naproxen

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Identification
Molecular formula
C14H14O3
CAS number
22204-53-1
IUPAC name
4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanoic acid
State
State

At room temperature, Naproxen is in a solid crystalline state. It is not very soluble in water but can dissolve in organic solvents like ethanol and acetone.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
230.26g/mol
Molar mass
230.2630g/mol
Density
1.1290g/cm3
Appearence
Naproxen is a white to off-white crystalline powder. It is odorless or may have a faint characteristic odor.
Comment on solubility

Solubility of 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanoic acid

4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanoic acid, often referred to as a derivative of naphthalene-1-acetic acid, showcases unique solubility characteristics due to its complex structure. Understanding its solubility in various solvents is crucial for applications across different fields such as pharmaceuticals and organic chemistry.

Solubility Characteristics:

  • Water Solubility: This compound exhibits limited solubility in water due to its large hydrophobic naphthyl group, making interactions with polar solvents less favorable.
  • Organic Solvents: It tends to be more soluble in non-polar and slightly polar organic solvents, such as ethanol, dichloromethane, and acetone.
  • pH Dependence: Its acid nature suggests that solubility might increase in basic conditions where the compound can deprotonate, forming an anionic species that can interact more favorably with polar solvents.

Overall, the solubility of 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanoic acid is influenced by structural factors and environmental conditions. Proper selection of solvent is essential for optimizing its use in various applications.

Interesting facts

Exploring 4-(Dimethylamino)-2-ethyl-2-(1-naphthyl)butanoic Acid

The compound 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanoic acid is captivating not only for its structural complexity but also for its diverse applications in the field of chemistry and pharmacology. Here are some intriguing details about this compound:

  • Pharmaceutical Relevance: This compound is acknowledged for its role as an important component in pharmaceutical research, particularly in the development of drugs targeting various biological pathways.
  • Unique Structure: The presence of a 1-naphthyl group contributes to its aromatic character, enhancing its interactions within biological systems.
  • Dimethylamino Group: The dimethylamino functional group lends the molecule its basicity, affecting its ability to interact with receptors in the body. This makes it an interesting candidate for studies in drug design.
  • Potential Applications: Research involving this compound includes studies on anti-inflammatory properties and potential analgesic effects, demonstrating its versatility in medicinal chemistry.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the structure of this compound can influence its biological activity is a critical area of investigation, providing insights into the design of more effective therapeutic agents.

In conclusion, 4-(dimethylamino)-2-ethyl-2-(1-naphthyl)butanoic acid represents a rich field of study, as it not only encapsulates intricate chemical behavior but also holds promise for innovative pharmaceutical developments. Its dual nature as a synthetic compound and a potential therapeutic agent makes it an exciting subject for future research.