Skip to main content

Loperamide

ADVERTISEMENT
Identification
Molecular formula
C29H33ClN2O2
CAS number
53179-11-6
IUPAC name
4-(dimethylamino)-2-methyl-2-phenyl-butanamide
State
State

Loperamide is a solid at room temperature, typically existing as a crystalline powder.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.00
Boiling point (Celsius)
435.76
Boiling point (Kelvin)
708.91
General information
Molecular weight
477.03g/mol
Molar mass
477.0330g/mol
Density
1.3140g/cm3
Appearence

Loperamide is typically observed as a white to slightly off-white crystalline powder.

Comment on solubility

Solubility of 4-(dimethylamino)-2-methyl-2-phenyl-butanamide

The solubility of 4-(dimethylamino)-2-methyl-2-phenyl-butanamide can be influenced by several factors, due to its unique molecular structure. Understanding its solubility characteristics is essential for its application in various fields. Here are some key points to consider:

  • Polarity: This compound exhibits a significant degree of polarity because of the dimethylamino group, which often enhances its solubility in polar solvents.
  • Solvent Interaction: Due to its structure, it is expected to be soluble in organic solvents such as alcohols and ethers, while potentially having limited solubility in water.
  • Hydrogen Bonding: The presence of the amide functionality means that the compound can participate in hydrogen bonding, which could facilitate solubility in polar solvents.
  • Temperature Dependence: Solubility can also vary with temperature; generally, increasing temperature may enhance solubility for many organic compounds.

In summary, the solubility behavior of 4-(dimethylamino)-2-methyl-2-phenyl-butanamide is closely tied to its molecular characteristics. As such, empirical testing in various solvents is recommended to accurately determine its solubility profile.

Interesting facts

Exploring 4-(dimethylamino)-2-methyl-2-phenyl-butanamide

4-(dimethylamino)-2-methyl-2-phenyl-butanamide, commonly known within scientific circles for its intriguing properties, is a compound with significant relevance in both medicinal chemistry and organic synthesis.

Key Features

  • Structural Significance: This compound features a unique amide functional group, which contributes to its solvent interactions and biological activity.
  • Biological Activity: Compounds with similar structures have been studied for their potential as antidepressants, anxiolytics, and even as anti-cancer agents.
  • Dimethylamino Group: The presence of the dimethylamino moiety imparts basic properties, enhancing its interaction with biological systems, making it a subject of interest in drug development.

Scientific Implications

Understanding the behavior of 4-(dimethylamino)-2-methyl-2-phenyl-butanamide in different contexts can provide insights into:

  • Drug design: Modifications to enhance efficacy or reduce side effects.
  • Synthetic pathways: Opportunities for creating related compounds with desirable characteristics.
  • Pharmacodynamics: How the structure translates to its action on biological targets.

Quote for Consideration

As famed chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." This resonates well within the context of exploring compounds like 4-(dimethylamino)-2-methyl-2-phenyl-butanamide, where the potential for discovery is boundless.

In conclusion, the exploration of 4-(dimethylamino)-2-methyl-2-phenyl-butanamide not only showcases the complexity of organic compounds but also emphasizes the exciting possibilities that arise in the field of drug development and molecular biology.

Synonyms
2977-16-4
BRN 2807353
BUTYRAMIDE, 4-(DIMETHYLAMINO)-2-METHYL-2-PHENYL-
alpha-Methyl-alpha-(2-dimethylaminoethyl)phenylacetamide
DTXSID80952194
4-(Dimethylamino)-2-methyl-2-phenylbutanimidic acid