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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23ClN2O
CAS number
6108-05-0
IUPAC name
4-(dimethylamino)-2,2-diphenyl-pentanamide;hydrochloride
State
State

At room temperature, lidocaine hydrochloride is in a solid state. It is commonly dissolved in water or other solvents for use in medical applications.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
270.80g/mol
Molar mass
270.7990g/mol
Density
1.1650g/cm3
Appearence

Lidocaine hydrochloride is a white, crystalline powder. It is odorless and has a slightly bitter taste. The crystals are typically small and can appear as a fine powder.

Comment on solubility

Solubility of 4-(dimethylamino)-2,2-diphenyl-pentanamide; hydrochloride

The solubility of 4-(dimethylamino)-2,2-diphenyl-pentanamide; hydrochloride is an intriguing topic due to its unique properties. As a quaternary ammonium compound, it is generally expected to exhibit specific solubility characteristics.

Key Points on Solubility:

  • Hydrochloride Form: The presence of a hydrochloride group typically enhances solubility in polar solvents, particularly water.
  • Polar and Nonpolar Characteristics: Given its structure, which includes both polar (amino group) and nonpolar (aromatic rings) features, solubility can vary greatly depending on the medium.
  • Solvation: In aqueous environments, the ionized form allows for strong interactions with water molecules, facilitating dissolution.

As a rule of thumb, it can be quoted that, “the more polar a compound, the greater its ability to dissolve in polar solvents.” This means that while 4-(dimethylamino)-2,2-diphenyl-pentanamide; hydrochloride is likely to be quite soluble in water, its solubility in nonpolar solvents will be drastically reduced.

In summary, the solubility of this compound is influenced by its ionic nature and structural components, making it predominantly soluble in water while showing limited solubility in organic solvents.

Interesting facts

Interesting Facts about 4-(Dimethylamino)-2,2-diphenyl-pentanamide; Hydrochloride

4-(Dimethylamino)-2,2-diphenyl-pentanamide; hydrochloride is a fascinating compound that has drawn the attention of researchers in various fields, particularly in pharmaceuticals and organic chemistry. Here are some compelling insights:

  • Pharmaceutical Relevance: This compound may play a role as an intermediate in the synthesis of biologically active molecules, contributing to the development of new medications.
  • Structural Significance: The presence of a dimethylamino group greatly influences the compound's reactivity and interaction with biological targets, positioning it as a candidate for drug design.
  • Chirality Considerations: This compound can exhibit chiral characteristics, making it essential to study its stereoisomers since different enantiomers can have vastly different biological activities.
  • Synthetic Versatility: The synthetic pathways to obtain this compound can utilize various methodologies, showcasing the versatility inherent in organic synthesis.
  • Research Potential: Studies involving this compound can lead to insights into its mechanism of action, broaden its applications, and explore its pharmacokinetic properties.

As a student or researcher, understanding such a compound can open up a wide array of scientific inquiries:

  1. How does the dimethylamino substitution affect its pharmacological profile?
  2. What are the implications of the diphenyl moieties in drug interactions?
  3. Can this compound serve as a template for synthesizing other therapeutic agents?

In conclusion, 4-(dimethylamino)-2,2-diphenyl-pentanamide; hydrochloride holds significant promise in the realm of medicinal chemistry and offers exciting opportunities for further research. Its unique structure and potential applications invite scientists to explore and innovate.

Synonyms
AMINOPENTAMIDE HYDROCHLORIDE
dl-Aminopentamide hydrochloride
2019-75-2
H1HPQ055F3
NIOSH/YV4385700
Valeramide, 4-(dimethylamino)-2,2-diphenyl-, hydrochloride
YV43857000
4-(Dimethylamino)-2,2-diphenylvaleramide monohydrochloride
Valeramide, 4-(dimethylamino)-2,2-diphenyl-, monohydrochloride
dl-Aminopentamide HCl
UNII-H1HPQ055F3
AMINOPENTAMIDE HCL
4-(dimethylamino)-2,2-diphenylpentanamide hydrochloride
DTXSID40942258
AMINOPENTAMIDE HYDROCHLORIDE, DL-
Q27279497
4-(Dimethylamino)-2,2-diphenylpentanimidic acid--hydrogen chloride (1/1)