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Propofol

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Identification
Molecular formula
C12H18O
CAS number
2078-54-8
IUPAC name
4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol
State
State

At room temperature, propofol is an oily liquid. It is formulated as an emulsion for usage in intravenous injections.

Melting point (Celsius)
18.00
Melting point (Kelvin)
291.15
Boiling point (Celsius)
256.00
Boiling point (Kelvin)
529.15
General information
Molecular weight
178.27g/mol
Molar mass
178.2740g/mol
Density
1.0040g/cm3
Appearence

Propofol appears as a colorless oil at room temperature. It is commonly emulsified as a creamy, white, intravenous formulation for medical applications.

Comment on solubility

Solubility of 4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol

4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol, often referred to as a substituted phenol, exhibits interesting solubility characteristics that can affect its applications in various fields.

Solubility Characteristics:

  • Polarity Influence: Due to the presence of the dimethylamino group, this compound has some polar characteristics; hence, it could be moderately soluble in polar solvents.
  • Hydrophobic Attributes: The isopropyl groups provide hydrophobic regions that can lead to limited solubility in water but enhance solubility in organic solvents.
  • Solvent Interactions: It is likely to be soluble in solvents such as ethanol, acetone, and other organic solvents, while demonstrating poor solubility in water.

In summary, the solubility of 4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol is greatly influenced by its structure. This results in a compound that exhibits:

  1. Moderate solubility in polar solvents
  2. Poor solubility in water
  3. Better solubility in organic solvents

Understanding these solubility parameters is crucial for effective application in chemical processes and formulations.

Interesting facts

Interesting Facts about 4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol

4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol, often referred to in the scientific community for its intriguing properties, falls under the category of organo-phosphorus compounds. Here are some captivating insights about this compound:

  • Unique Structure: The compound features a complex arrangement that includes both an amino and a hydroxy group, which significantly contributes to its reactivity and interaction with biological systems.
  • Biological Relevance: Compounds similar in structure are often studied for their roles as potential pharmaceutical agents, particularly in the fields of neurobiology and pharmacology, due to their ability to interact with neurotransmitter systems.
  • Synthesis Pathways: The synthesis of 4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol can be achieved through various organic reactions, including Friedel-Crafts alkylation and amination processes. This opens up several routes for chemists to modify its properties.
  • Applications in Research: This compound is frequently utilized as an intermediate in the synthesis of more complex molecules and can serve as a useful building block in medicinal chemistry.

Due to its fascinating chemical characteristics, 4-[(dimethylamino)methyl]-2,6-diisopropyl-phenol stands out in both academic research and practical applications, paving the way for insights into innovative therapeutic strategies.

As one prominent chemist once said, "The true beauty of chemistry lies in its potential to transform substances into something greater." This compound exemplifies that beauty, as it bridges fundamental chemical principles with real-world applications.

Synonyms
4918-95-0
4-((dimethylamino)methyl)-2,6-diisopropylphenol
4-[(Dimethylamino)methyl]-2,6-diisopropylbenzenol
4-[(dimethylamino)methyl]-2,6-di(propan-2-yl)phenol
CHEMBL55756
p-CRESOL, alpha-(DIMETHYLAMINO)-2,6-DIISOPROPYL-
2,6-Diisopropyl-4-((dimethylamino)methyl)phenol
2,6-Diisopropyl-4-[(dimethylamino)methyl]phenol
4-[(dimethylamino)methyl]-2,6-diisopropylphenol
3-Hydroxybenzyldimethylamine hydrochloride
NSC 68328
BRN 2939746
alpha-(Dimethylamino)-m-cresol hydrochloride
alpha-(Dimethylamino)-2,6-diisopropyl-p-cresol
MFCD00514869
CBMicro_016910
Oprea1_662916
4-13-00-02008 (Beilstein Handbook Reference)
SCHEMBL5569907
DTXSID40197701
CCG-5900
NSC68328
BDBM50064429
NSC-68328
AKOS005072129
CA-0871
SB81149
BIM-0016911.P001
4-Dimethylaminomethyl-2,6-diisopropyl-phenol
CS-0332008
AB00080269-01
4-[(dimethylamino)methyl]-2,6-bis(propan-2-yl)phenol