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BZP (Benzylpiperazine)

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Identification
Molecular formula
C18H17NO3
CAS number
27515-41-9
IUPAC name
[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]-phenyl-methanone
State
State

At room temperature, the compound is typically in a solid state, often as a crystalline powder or solid chunk.

Melting point (Celsius)
188.00
Melting point (Kelvin)
461.00
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.00
General information
Molecular weight
285.32g/mol
Molar mass
285.3200g/mol
Density
1.1100g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It might also be available as a solidified form or in tablet form when used in non-research settings. The crystalline form gives it a slightly shiny appearance under light.

Comment on solubility

Solubility of [4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]-phenyl-methanone

The solubility of the compound [4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]-phenyl-methanone can be influenced by several factors due to its complex structure. Understanding its solubility is crucial for applications in fields such as pharmaceuticals and material science. Here are some key points to consider:

  • Solvent Polarity: The polarity of the solvent plays a significant role in the solubility of this compound. Polar solvents, such as water or methanol, may provide varying degrees of solubility based on the presence of functional groups.
  • Hydrophilicity vs. Hydrophobicity: The balance between hydrophilic and hydrophobic portions of the molecule affects its interaction with solvents. For instance:
    • The -OH group indicates potential for hydrogen bonding, suggesting increased solubility in polar solvents.
    • Conversely, aromatic rings contribute to hydrophobic character, potentially leading to lower solubility in highly polar environments.
  • pH Sensitivity: The solubility may change with pH, particularly due to the presence of functional groups which may ionize in acidic or basic media.
  • Temperature Dependence: Solubility can also vary with temperature, often increasing with rising temperatures for many organic compounds.

In summary, while predicting the solubility of [4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]-phenyl-methanone involves considering interactions with solvents, functional group behavior, and environmental conditions, its complete solubility profile can be complex and multifaceted. It is often recommended to conduct solubility tests in various solvents and at different temperatures to establish practical solubility data.

Interesting facts

Interesting Facts About [4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]-phenyl-methanone

This intriguing compound, often referred to in research contexts, showcases the fascinating intersection of organic chemistry and pharmaceutical applications. Its unique structure incorporates a benzofuran moiety, which is known for its biological activity, particularly in medicinal chemistry. Here are some interesting facets of this compound:

  • Complex Structure: The presence of both phenyl and benzofuran rings creates a multifaceted compound, enabling varied interactions with biological targets.
  • Biological Activity: Compounds with benzofuran structures have been studied for their potential as therapeutic agents, particularly in the areas of anti-inflammatory and anti-cancer research.
  • Dimethylamino Group: The dimethylamino functionality enhances the compound's ability to engage in molecular interactions, augmenting its pharmacological profile.
  • Hydroxy Group Impact: The hydroxy group at the 5-position contributes to the compound's reactivity and solubility characteristics, serving as a potential site for further chemical modification.
  • Research Implications: Ongoing research explores the derivative’s potential applications in drug development, showcasing its promise in synthesizing high-impact pharmaceuticals.

The synthesis and study of this compound emphasize the significant role that detailed chemical design plays in advancing medicinal chemistry. As noted by researchers, "the relationship between molecular structure and biological activity is a profound realm that drives innovation in drug discovery."

Overall, [4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]-phenyl-methanone exemplifies how subtle changes in molecular architecture can lead to significant biological implications, igniting curiosity and exploration within the scientific community.

Synonyms
MLS000060844
SMR000069709
{4-[(dimethylamino)methyl]-5-hydroxy-1-benzofuran-3-yl}(phenyl)methanone
Oprea1_728778
cid_34611
CHEMBL1531553
BDBM68546
HMS2448N10
STK524610
AKOS005458781
SR-01000209989
3-benzoyl-4-dimethylaminomethyl-5-hydroxybenzofuran
SR-01000209989-1
[4-[(dimethylamino)methyl]-5-hydroxy-1-benzofuran-3-yl]-phenylmethanone
[4-[(dimethylamino)methyl]-5-hydroxy-3-benzofuranyl]-phenylmethanone
[4-[(dimethylamino)methyl]-5-hydroxy-benzofuran-3-yl]-phenyl-methanone
[4-[(dimethylamino)methyl]-5-oxidanyl-1-benzofuran-3-yl]-phenyl-methanone