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Michler's ketone

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Identification
Molecular formula
C15H15NO
CAS number
90-94-8
IUPAC name
[4-(dimethylamino)phenyl]-phenyl-methanone
State
State

At room temperature, Michler's ketone is in solid state, appearing as crystals or powder.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
407.00
Boiling point (Kelvin)
680.15
General information
Molecular weight
225.30g/mol
Molar mass
268.3470g/mol
Density
1.2100g/cm3
Appearence

Michler's ketone appears as a white to pale yellow crystalline solid. It may also appear as light yellow or colorless crystals depending on its purity. It has a faint odor and is usually supplied in a powder form.

Comment on solubility

Solubility of [4-(dimethylamino)phenyl]-phenyl-methanone

The solubility of [4-(dimethylamino)phenyl]-phenyl-methanone can be quite intriguing due to its unique structural features. This compound, which includes both an aromatic ring and a dimethylamino group, exhibits solubility that can depend on the nature of the solvent used. Here are some important points to consider:

  • Polar Solvents: Compounds with polar functional groups, like amines, often exhibit greater solubility in polar solvents. Thus, [4-(dimethylamino)phenyl]-phenyl-methanone may dissolve well in solvents such as water or alcohol.
  • Non-Polar Solvents: Conversely, its aromatic characteristics may allow for enhanced solubility in non-polar solvents like benzene or hexane, although the extent of this solubility may vary.
  • Temperature Effects: The solubility of many organic compounds typically increases with temperature. Therefore, heating the solution might improve solubility in both types of solvents.
  • pH Influence: The basic nature of the dimethylamino group could lead to pH-dependent solubility, especially in acidic or basic environments, affecting its ionization state and, hence, solubility.

As a general rule, the overall solubility characteristics are influenced by multiple factors, including molecular structure, environmental conditions, and the presence of other solutes in the solution. Thus, while [4-(dimethylamino)phenyl]-phenyl-methanone can be expected to have reasonable solubility in certain solvents, it is critical to consider these variables for precise predictions.

Interesting facts

Interesting Facts about [4-(dimethylamino)phenyl]-phenyl-methanone

[4-(dimethylamino)phenyl]-phenyl-methanone, often referred to as a member of the diarylmethanone family, is a fascinating compound notable for its diverse applications in various fields. Here are some intriguing points:

  • Versatile Intermediate: This compound serves as a versatile intermediate in organic synthesis, making it an important building block for various chemical reactions. Its structure facilitates reactions such as nucleophilic substitutions and electrophilic aromatic substitutions.
  • Pharmaceutical Relevance: The presence of the dimethylamino group contributes to its bioactivity, allowing it to interact with biological systems. Compounds like this have been explored in the development of pharmaceuticals, particularly in the realm of antimicrobial and anti-cancer drugs.
  • Colorimetric Indicators: Notably, due to the presence of its aromatic structure, this compound can act as a colorimetric indicator, providing visual changes in response to chemical environments, making it valuable in sensor technology.
  • Significant Derivatives: The derivatives of this compound are widely studied for their properties, leading to the development of novel materials in organic electronics and photovoltaics.
  • Research Potential: Scientists are interested in the compound's photophysical properties, which might be harnessed for applications in fluorescence microscopy and bioluminescence imaging.

In summary, [4-(dimethylamino)phenyl]-phenyl-methanone exemplifies a compound with substantial relevance in both practical applications and academic research. As noted in the words of one chemist, “This is more than just a molecule; it’s a key to unlocking further innovations in science.”

Synonyms
4-(DIMETHYLAMINO)BENZOPHENONE
p-Dimethylaminobenzophenone
4-Dimethylaminobenzophenone
4-benzoyl-N,N-dimethylaniline
Methanone, [4-(dimethylamino)phenyl]phenyl-
EINECS 208-478-4
UNII-G8988HD9YE
NSC 15962
G8988HD9YE
Methanone, (4-(dimethylamino)phenyl)phenyl-
NSC-15962
NSC-28935
DTXSID1060188
N,N-DIMETHYL-P-AMINOBENZOPHENONE
P-DIMETHYLAMINOBENZOPHENONE [MI]
Benzenamine,N,N-dimethyl-4-(phenylmethanone)-
(4-(DIMETHYLAMINO)PHENYL)PHENYLMETHANONE
DTXCID7041334
beugbyxjxmvrfo-uhfffaoysa-n
530-44-9
(4-(dimethylamino)phenyl)(phenyl)methanone
p-Benzoyl-N,N-dimethylaniline
Benzophenone, 4-(dimethylamino)-
4-N,N-Dimethylaminobenzophenone
[4-(dimethylamino)phenyl]-phenylmethanone
4-(dimethylamino)phenyl phenyl ketone
[4-(Dimethylamino)phenyl](phenyl)methanone
p-(Dimethylamino)benzophenone
(4-dimethylamino-phenyl)-phenyl-methanone
MFCD00008311
4-dimethylamino-benzophenone
Oprea1_295432
SCHEMBL43585
MLS000564300
BIDD:GT0595
4-(dimethylamino)-benzophenone
CHEMBL1502306
HMS1607I17
HMS2408D11
NSC15962
NSC28935
4-(Dimethylamino)benzophenone, 98%
BBL027707
CCG-46502
STL146478
AKOS001053239
FD41618
NCGC00246075-01
AS-65378
SMR000151805
DB-052241
CS-0197262
D2561
EU-0066744
NS00032635
[4-(Dimethylamino)phenyl](phenyl)methanone #
EN300-17355
D90083
AH-034/32471008
SR-01000389029
SR-01000389029-1
SR-01000389029-2
BRD-K39777924-001-09-7
Q27278927
Z56922119
F0349-2872