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4-(dimethylsulfamoyl)benzoic acid

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Identification
Molecular formula
C9H11NO4S
CAS number
35953-85-2
IUPAC name
4-(dimethylsulfamoyl)benzoic acid
State
State

At room temperature, 4-(dimethylsulfamoyl)benzoic acid is in a solid state.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
482.00
Boiling point (Kelvin)
755.15
General information
Molecular weight
229.27g/mol
Molar mass
229.2710g/mol
Density
1.3900g/cm3
Appearence

4-(Dimethylsulfamoyl)benzoic acid typically appears as a crystalline solid. The crystals are white to off-white in color.

Comment on solubility

Solubility of 4-(dimethylsulfamoyl)benzoic acid

4-(dimethylsulfamoyl)benzoic acid, often recognized for its unique structural properties, exhibits interesting solubility characteristics within various solvents. When examining its solubility, it’s essential to consider the following key aspects:

  • Polar Solvents: This compound is generally soluble in polar solvents such as water and methanol due to its sulfonamide group, which enhances its ability to form hydrogen bonds.
  • Non-Polar Solvents: Conversely, it is less soluble in non-polar solvents like hexane or toluene, as the hydrophobic interactions dominate in such environments.
  • Temperature Dependency: The solubility can also increase with temperature, making it more soluble in heated solvents, which can be a crucial factor in chemical reactions or formulations.

In summary, the solubility of 4-(dimethylsulfamoyl)benzoic acid largely depends on solvent polarity and temperature conditions. As such, for optimal solubility, it is advisable to utilize polar solvents and consider thermal adjustments, thereby ensuring efficient dissolution and subsequent applications in chemical processes.

Interesting facts

Interesting Facts about 4-(Dimethylsulfamoyl)benzoic Acid

4-(Dimethylsulfamoyl)benzoic acid, a fascinating compound, belongs to the class of sulfonamides. This compound boasts a unique structural arrangement that leads to interesting properties and applications:

  • Pharmaceutical Applications: This compound is particularly important in the field of medicinal chemistry. It serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those with anti-inflammatory and antibacterial properties.
  • Versatile Chemistry: The presence of the dimethylsulfamoyl group enhances the compound's reactivity, making it a valuable building block for creating more complex molecular architectures.
  • Environmental Impact: Sulfonamide compounds, including this one, have received attention for their persistence in the environment. Understanding their degradation pathway is essential for assessing their ecological impact.
  • Prodrug Development: Compounds like 4-(dimethylsulfamoyl)benzoic acid can act as prodrugs, where the active drug compound is released in the body after metabolic conversion, providing benefits such as improved solubility and reduced toxicity.
  • Research Potential: Ongoing research is being conducted to explore the efficacy of sulfonamides in treating various health conditions, establishing new therapeutic avenues for diseases that are resistant to conventional treatments.

In summary, 4-(dimethylsulfamoyl)benzoic acid is not just an ordinary compound; its role in medicinal chemistry and environmental studies makes it a subject of significant scientific interest. As we continue to uncover its potential and applications, we realize that the small intricacies of molecular compounds can lead to substantial advancements in science and technology.

Synonyms
4-[(Dimethylamino)sulfonyl]benzoic acid
4-(dimethylsulfamoyl)benzoic acid
4-((Dimethylamino)sulfonyl)benzoic acid
827-117-7
1206-37-7
4-(N,N-Dimethylsulfamoyl)benzoic acid
4-Dimethylsulfamoyl-benzoic acid
p-(Dimethylsulfamoyl)benzoic acid
BENZOIC ACID, p-(DIMETHYLSULFAMOYL)-
Benzoic acid, 4-((dimethylamino)sulfonyl)-
MFCD00721975
Benzoic acid, 4-[(dimethylamino)sulfonyl]-
BRN 2731901
AI3-24676
4-(N,N-Dimethylsulfamoyl)benzoicacid
Oprea1_237320
Oprea1_741375
SCHEMBL34672
p-dimethylsulfamylbenzoic acid
4-dimethylsulfamoylbenzoic acid
DTXSID90152921
ALBB-012769
4-(dimethylaminosulfonyl)benzoic acid
BBL008617
STK696347
AKOS000112061
SB80258
BS-13990
SY131906
4-[(Dimethylamino)sulfonyl]benzoic acid #
EU-0099885
EN300-00386
W10216
AQ-390/11215904
SR-01000596888
SR-01000596888-1
Z53038379
F0347-1659
F1386-0334