4-Ethoxyaniline | Solubility of Things

Identification

Molecular formula

C₈H₁₁NO

CAS number

156-43-4

IUPAC name

4-ethoxyaniline

State

Solid at room temperature, typically in the form of crystalline powder or needles with an off-white to beige color.

Melting point (Celsius)

53.00

Melting point (Kelvin)

326.15

Boiling point (Celsius)

243.00

Boiling point (Kelvin)

516.15

General information

Molecular weight

137.19g/mol

Molar mass

137.1850g/mol

Density

0.9950g/cm³

Appearence

4-Ethoxyaniline is typically found in a solid state at room temperature. It can appear as off-white to beige crystalline powder or needles. It may darken upon exposure to air and light over time.

Comment on solubility

Solubility of 4-ethoxyaniline

4-ethoxyaniline, with its chemical formula C₁₀H₁₅NO, exhibits a notable solubility profile that is important in various applications. This compound is classified as an aromatic amine, and its solubility can be understood through the following points:

Solvent Polarity: 4-ethoxyaniline typically demonstrates good solubility in polar organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). However, it has limited solubility in non-polar solvents like hexane.
pH Sensitivity: The solubility of 4-ethoxyaniline can be affected by pH levels. In acidic conditions, it can form soluble salts, enhancing its solubility.
Temperature Dependency: Like many organic compounds, the solubility of 4-ethoxyaniline tends to increase with rising temperatures. This can be crucial for applications requiring precise solute concentrations.

In conclusion, 4-ethoxyaniline's solubility characteristics render it useful in various chemical processes, especially in organic synthesis and dye manufacturing. It is important to consider both the solvent choice and environmental conditions when working with this compound to achieve optimal results.

Interesting facts

Interesting Facts about 4-Ethoxyaniline

4-Ethoxyaniline, known for its significant role in the synthesis of various chemical compounds, belongs to the group of ethoxyanilines. Here are some notable aspects of this compound:

Applications in Dye Production: 4-Ethoxyaniline is a precursor in the manufacture of azo dyes, which are widely used in textiles, foods, and pharmaceuticals. Dyes derived from this compound often exhibit vivid colors and excellent stability.
Role in Pharmaceuticals: Its derivatives can serve as important building blocks in the development of pharmaceuticals, showcasing the versatility of 4-ethoxyaniline in medicinal chemistry.
Research Significance: It is actively studied for its chemical properties and potential applications in material science, including polymers and nanomaterials.
Safety Precautions: As with many anilines, handling 4-ethoxyaniline requires caution, as it can be harmful. Personal protective equipment (PPE) is essential when working with this compound.

In summary, the utility of 4-ethoxyaniline extends beyond its basic chemical makeup, as it serves as a critical component in various industries and research fields. Its role as a dye precursor and a stepping stone in drug development highlights its importance in both chemistry and applied sciences. As the fields of organic and synthetic chemistry evolve, 4-ethoxyaniline will likely continue to play a vital part.

Synonyms

p-Phenetidine

4-ETHOXYANILINE

156-43-4

Phenetidine

4-Aminophenetole

p-Ethoxyaniline

Benzenamine, 4-ethoxy-

p-Phenetidin

p-Aminophenetole

4-Ethoxybenzenamine

Phenethidine

Aniline, p-ethoxy-

1-Amino-4-ethoxybenzene

4-Phenetidine

4-Aminoethoxybenzene

p-Aminofenetol

p-Fenetidin

Ethyl p-aminophenol

p-Fenetidin [Czech]

p-Aminofenetol [Czech]

4-ETHOXY-ANILINE

4-Ethoxybenzeneamine

NSC 3116

CCRIS 2878

p-aminophenyl ethyl ether

EINECS 205-855-5

9TSL224ZSE

p-aminoethoxybenzene

CP 5685

BRN 0606666

Aniline, 4-ethoxy-

DTXSID0025864

CHEBI:85505

Para-aminoethoxybenzene

AI3-09042

PHENETIDINE, P-

NSC-3116

P-ETHOXYPHENYLAMINE

4-aminophenyl ethyl ether

MFCD00007865

P-PHENETIDINE [MI]

DTXCID505864

EC 205-855-5

4-13-00-01017 (Beilstein Handbook Reference)

4-ethoxyphenylamine

CAS-156-43-4

UNII-9TSL224ZSE

phenetylamine

pAminofenetol

pAminophenetole

paraPhenetidine

pEthoxyaniline

pFenetidin

pPhenetidin

4ethoxyaniline

4Aminophenetole

4Phenetidine

para-phenetidine

4-ethoxyanilin

Aniline, pethoxy

4Ethoxybenzenamine

4Ethoxyphenylamine

Ethyl paminophenol

4Aminoethoxybenzene

1Amino4ethoxybenzene

4-ethoxy-phenylamine

paraAminoethoxybenzene

PAMINOPHENETOL

Benzenamine, 4ethoxy

4Amino1ethoxy benzene

4ETHOXYANILIN

4PHENETIDIN

pAminophenyl ethyl ether

(4-ethoxyphenyl) amine

(4-ethoxyphenyl)-amine

4-Ethoxyaniline, 98%

1AMINO4ETHOXYBENZOL

4AMINO1ETHOXYBENZOL

4-Amino-1-ethoxy benzene

WLN: ZR DO2

4AMINOPHENOLETHYLETHER

4AMINOPHENYLETHYLETHER

SCHEMBL15703

P-PHENETIDINE [INCI]

MLS002454444

UN 2311 (Salt/Mix)

BIDD:GT0388

CHEMBL250969

NSC3116

HMS3041D03

STR01492

Tox21_201946

Tox21_303334

STK397546

AKOS000100572

FP26875

VS-0323

NCGC00091785-01

NCGC00091785-02

NCGC00257138-01

NCGC00259495-01

PD055436

SMR001252219

NS00011443

P0090

EN300-17982

E78819

Q27158608

Z57127438

F2190-0444

4-Ethoxybenzenamine;1-Amino-4-ethoxybenzene;4-Aminophenetole

205-855-5