(4-Ethoxyphenyl)urea | Solubility of Things

Identification

Molecular formula

C₉H₁₂N₂O₂

CAS number

2318-34-9

IUPAC name

(4-ethoxyphenyl)urea

State

(4-Ethoxyphenyl)urea is typically encountered as a solid at room temperature. Its stable crystalline nature makes it a solid under standard conditions, and it remains stable unless subjected to temperatures nearing its melting point.

Melting point (Celsius)

176.70

Melting point (Kelvin)

449.90

Boiling point (Celsius)

391.50

Boiling point (Kelvin)

664.60

General information

Molecular weight

180.21g/mol

Molar mass

180.2050g/mol

Density

1.2374g/cm³

Appearence

(4-Ethoxyphenyl)urea appears as a crystalline solid. It is typically white in color and can be characterized by its needle-like crystal structure. This compound may powder upon grinding and usually appears in a dry form unless exposed to moisture, where it can exhibit some level of clumping due to its hygroscopic nature.

Comment on solubility

Solubility of (4-ethoxyphenyl)urea

(4-ethoxyphenyl)urea, also known for its unique structural features, exhibits varying solubility characteristics in different solvents. Understanding its solubility behavior is crucial for practical applications in both laboratory and industrial settings.

Factors Influencing Solubility

The solubility of (4-ethoxyphenyl)urea can be influenced by several factors:

Polarity of Solvent: Since (4-ethoxyphenyl)urea contains a urea functional group, it can engage in hydrogen bonding, making it more soluble in polar solvents like water and alcohols.
Temperature: Typically, solubility increases with temperature. Thus, heating may enhance the dissolution of (4-ethoxyphenyl)urea in its suitable solvents.
Concentration: As with many compounds, a higher concentration of solvent can facilitate better solubility.

Solubility Characteristics

The solubility of (4-ethoxyphenyl)urea can be summarized as follows:

In water: It exhibits moderate solubility due to the presence of polar functional groups, which can interact favorably with water molecules.
In organic solvents: This compound is generally soluble in organic solvents such as ethanol and acetone, where the non-polar ethoxy group can better interact.

In conclusion, the solubility of (4-ethoxyphenyl)urea is a nuanced property that depends on a variety of factors. Understanding these can lead to more effective applications and utilization of this compound in various fields.

Interesting facts

Interesting Facts about (4-ethoxyphenyl)urea

(4-ethoxyphenyl)urea is a fascinating compound with a variety of applications in both research and industry. Here are some interesting facts:

Chemical Structure: This compound consists of a urea functional group attached to a phenyl ring with an ethoxy substituent, enhancing its solubility and reactivity. The unique structure allows for interesting interactions with other substances.
Role in Research: (4-ethoxyphenyl)urea is often utilized in medicinal chemistry, especially in the design of pharmaceuticals. Scientists study its properties to understand how modifications to its structure might enhance biological activity.
Biological Activities: Some studies suggest that compounds similar to (4-ethoxyphenyl)urea exhibit notable antibacterial and antifungal properties. This could lead to potential applications in developing new therapeutic agents.
Versatile Applications: Beyond pharmaceuticals, (4-ethoxyphenyl)urea is helpful in agricultural chemistry, where it may serve as a growth regulator or herbicide, demonstrating its versatility across various scientific fields.
Reaction Studies: This compound can undergo various chemical reactions, such as condensation and substitution. Such reactions are essential for synthetic organic chemistry and can lead to the creation of other useful compounds.
Importance in Drug Design: The incorporation of the ethoxy group improves lipophilicity, significantly impacting absorption and distribution in biological systems, a crucial factor in drug development.

In summary, (4-ethoxyphenyl)urea serves as a significant example of how small changes in chemical structure can lead to vast differences in functionality and application. As research continues to unveil its properties, we can expect to see more innovative uses for this intriguing compound!

Synonyms

Dulcin

150-69-6

1-(4-Ethoxyphenyl)urea

N-(4-Ethoxyphenyl)urea

(4-ethoxyphenyl)urea

Sucrol

Valzin

p-Ethoxyphenylurea

p-Phenetylurea

Phenetolcarbamide

Dulcine

Suesstoff

Dulein

p-Phenetolcarbamide

p-Phenethylurea

p-Phenetolecarbamide

4-ETHOXYPHENYLUREA

Urea, (p-ethoxyphenyl)-

Phenethylcarbamid

p-Phenetolcarbamid

Urea, (4-ethoxyphenyl)-

p-Aethoxyphenylharnstoff

4-Ethoxy-phenylurea

p-Ethoxyfenylmocovina

NCI-C02073

Urea, N-(4-ethoxyphenyl)-

Phenethylcarbamid [German]

p-Phenetolcarbamid [German]

NSC 1839

p-Ethoxyfenylmocovina [Czech]

CCRIS 5913

p-Aethoxyphenylharnstoff [German]

4-Ureidophenetole

EINECS 205-767-7

UNII-8U78KF577Z

BRN 2096445

DTXSID9020580

AI3-08931

HSDB 8048

8U78KF577Z

DULCIN [IARC]

NSC-1839

DULCIN [MI]

4-ETHOXYPHENYL)UREA

(P-ETHOXYPHENYL)UREA

DTXCID10580

CHEBI:82462

UREA,(4-ETHOXYPHENYL)-

4-13-00-01154 (Beilstein Handbook Reference)

DULCIN (IARC)

Phenethylcarbamid (German)

p-Phenetolcarbamid (German)

p-Ureidophenetole

Dulcin?

4-ethoxyphenyl urea

p-Phenetol-carbamide

MFCD00025431

p-Aethoxyphylharnstoff

(4-ethoxyphenyl)-urea

Maybridge1_002383

WLN: ZVMR DO2

DULCIN (SWEETENER)

PARA-PHENETOLECABAMIDE

Oprea1_621725

MLS000056892

DivK1c_001135

SCHEMBL177957

p-Aethoxyphylharnstoff (German)

CHEMBL1330343

HMS548E07

NSC1839

Urea, (4-ethoxyphenyl)-(9CI)

HMS2487K12

Urea, (4-ethoxyphenyl)- (9CI)

Tox21_301340

BBL004546

STK400289

AKOS000113528

HY-W150251

PS-4228

CDS1_000095

NCGC00255360-01

CAS-150-69-6

SMR000065473

CS-0206739

E1171

NS00021681

C19415

T71814

Q423302

Z56754688