Skip to main content

4-[ethyl-[2-(1H-indol-3-yl)ethyl]amino]butyl 3,4,5-trimethoxybenzoate

ADVERTISEMENT
Identification
Molecular formula
C26H34N2O5
CAS number
545-31-5
IUPAC name
4-[ethyl-[2-(1H-indol-3-yl)ethyl]amino]butyl 3,4,5-trimethoxybenzoate
State
State

At room temperature, this compound is typically a crystalline solid. It is stable under standard conditions and should be handled with care to avoid decomposition.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
430.00
Boiling point (Kelvin)
703.15
General information
Molecular weight
420.56g/mol
Molar mass
420.5100g/mol
Density
1.2400g/cm3
Appearence

The compound typically appears as a crystalline solid. Its exact appearance can vary depending on the particular formulation and method of synthesis. It may be colorless or possess a slight color depending on impurities or specific structural attributes.

Comment on solubility

Solubility of 4-[ethyl-[2-(1H-indol-3-yl)ethyl]amino]butyl 3,4,5-trimethoxybenzoate

The solubility of the compound 4-[ethyl-[2-(1H-indol-3-yl)ethyl]amino]butyl 3,4,5-trimethoxybenzoate can be quite complex due to its intricate molecular structure. This compound features both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, impacting its overall solubility in various solvents. Key points to consider include:

  • Hydrophobic Nature: The presence of multiple aromatic rings can lead to increased hydrophobic interactions, making the compound less soluble in polar solvents like water.
  • Polar Functional Groups: The methoxy groups in the structure can enhance solubility in organic solvents, providing a degree of compatibility with less polar environments.
  • pH Sensitivity: The solubility may be influenced by pH, particularly due to any amino groups present that can accept or donate protons, thus affecting protonation states.
  • Temperature Effects: As with many organic compounds, increasing temperature may increase solubility in solvents, a critical factor for practical applications.

In conclusion, while this compound might exhibit limited solubility in water, it is likely to be more soluble in non-polar to moderately polar organic solvents, influenced by both temperature and pH conditions. Understanding these aspects of solubility is essential for its applications in pharmacology and organic synthesis.

Interesting facts

Interesting Facts about 4-[ethyl-[2-(1H-indol-3-yl)ethyl]amino]butyl 3,4,5-trimethoxybenzoate

This compound is a fascinating example of a synthetic molecule that features a complex structure with potential implications in medicinal chemistry. As researchers delve into the properties and potential applications of this compound, several interesting aspects come to light:

  • Structure Complexity: The molecule consists of an indole ring—a structure known for its prevalence in natural products and pharmaceuticals—attached to an ethyl group. This combination hints at its possible biological activity due to the influence of the indole moiety.
  • Medicinal Potential: Compounds containing the indole structure often exhibit a variety of biological activities, including anticancer, antidepressant, and anti-inflammatory effects. This particular compound may have noteworthy properties yet to be explored in depth.
  • Functional Enhancements: The presence of the 3,4,5-trimethoxybenzoate group can enhance the lipophilicity and bioavailability of the compound, making it a candidate for drug development. Chemists often use such modifications to improve the pharmacokinetics of drug candidates.
  • Research Interest: Its unique formulation of amino group attachments on the butyl chain allows for potential interactions with various biological targets, inviting more research into its pharmacodynamics and mechanism of action.
  • Indole Revolution: The indole structure has been a cornerstone in drug design, with famous drugs like tryptophan, melatonin, and various antidepressants showcasing the versatility of this moiety.

Given these aspects, the study of 4-[ethyl-[2-(1H-indol-3-yl)ethyl]amino]butyl 3,4,5-trimethoxybenzoate opens up avenues for innovative research and development within pharmaceutical sciences. As the journey of discovery continues, it highlights the interconnected nature of chemistry and biology, revealing how synthetic compounds can pave the way for future therapies.

Synonyms
1061-89-8
BRN 0501898
Indole, 3-(N-ethyl-N-(4-hydroxybutyl)amino)ethyl-, 3,4,5-trimethoxybenzoate (ester)
DTXSID50147510
3-(N-Ethyl-N-(4-hydroxybutyl)amino)ethylindole 3,4,5-trimethoxybenzoate (ester)
Benzoic acid, 3,4,5-trimethoxy-, 4-(N-(2-indol-3-yl)ethyl-N-ethylamino)butyl ester
DTXCID2070001
4-[ethyl-[2-(1H-indol-3-yl)ethyl]amino]butyl 3,4,5-trimethoxybenzoate