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Betaxolol

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Identification
Molecular formula
C18H29NO3
CAS number
63659-18-7
IUPAC name
4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butan-1-ol
State
State

At room temperature, Betaxolol exists as a solid. It is commonly found as a powder and is not volatile under standard temperature and pressure conditions.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
400.20
Boiling point (Kelvin)
673.35
General information
Molecular weight
307.42g/mol
Molar mass
307.4180g/mol
Density
1.0399g/cm3
Appearence

Betaxolol usually appears as a white crystalline powder. It is odorless and has a bitter taste. The compound is often encountered as a hydrochloride salt in pharmaceutical formulations, which helps in its solubility and stability.

Comment on solubility

Solubility of 4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butan-1-ol

The solubility of 4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butan-1-ol is influenced by its unique chemical structure. This compound, which includes both hydrophilic and hydrophobic portions, exhibits interesting solubility characteristics.

Factors Affecting Solubility

  • Polar Groups: The presence of the butanol group suggests potential for hydrogen bonding with water, enhancing the solubility in aqueous environments.
  • Hydrophobic Phenyl Ring: The 4-methoxyphenyl substituent may introduce hydrophobic interactions, which can lead to decreased solubility in water but enhanced solubility in organic solvents.
  • Alkyl Chains: The branched ethyl component can further complicate the solubility, potentially creating a balance between solubility in polar and non-polar solvents.

In summary, the solubility behavior of this compound can be described as:

  • Moderately soluble in water due to the presence of the hydrophilic -OH group.
  • More soluble in organic solvents such as ethanol and acetone, due to the non-polar regions of the molecule.

As a result, the solubility of 4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butan-1-ol reflects the delicate balance between its polar and non-polar functional groups, making it a compound of interest for various applications in both aqueous and organic phases.

Interesting facts

Interesting Facts about 4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butan-1-ol

This compound is a fascinating example of a synthetic organic molecule that showcases the intricate world of chemical design. Known for its potential applications in medicinal chemistry, this compound embodies several key attributes that are worth exploring:

  • Pharmacological Potential: Compounds like this often exhibit desirable biological activities, making them candidates for pharmaceutical research. The presence of a butanol moiety and an ethylamine side chain can influence their interaction with biological targets.
  • Structural Complexity: The structural diversity stemming from substituents such as the 4-methoxyphenyl group contributes to its unique properties. The incorporation of methoxy groups can enhance lipophilicity, affecting the compound's absorption and distribution in biological systems.
  • Biological Activity: Investigating such compounds often leads to insights into their mechanism of action in living organisms, which might involve modulation of neurotransmitter systems. Such compounds could either act as receptor agonists or antagonists.
  • Research Applications: The synthesis and characterization of this compound can provide valuable insights into drug design strategies. These strategies could be aimed at optimizing pharmacokinetic and pharmacodynamic profiles for therapeutic purposes.

Overall, 4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butan-1-ol not only serves as a model for studying the relationship between structure and activity but also emphasizes the creative side of chemistry where molecular design can lead to innovative solutions in medicine. As noted by renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This compound exemplifies that philosophy within the field of chemical synthesis and drug development.

Synonyms
Mebeverine alcohol
14367-47-6
2UK92XY6H9
4-(ETHYL(2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)-1-BUTANOL
MEBOH
Mebeverine metabolite Mebeverine alcohol
4-[ethyl-[1-(4-methoxyphenyl)propan-2-yl]amino]butan-1-ol
4-(Ethyl(1-(4-methoxyphenyl)propan-2-yl)amino)butan-1-ol
BRN 2735398
4-{ETHYL[1-(4-METHOXYPHENYL)PROPAN-2-YL]AMINO}BUTAN-1-OL
1-Butanol, 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-; 1-Butanol, 4-[ethyl(p-methoxy-a-methylphenethyl)amino]- (6CI,7CI,8CI); 4-[Ethyl[2-(p-methoxy-a-phenyl)-1-methylethyl]amino]-1-butanol; 4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-1-butanol; 4-[Ethyl[(2RS)-1-(4-methoxyphenyl)propan-2-yl]amino]butan-1-ol; Mebeverine Impurity C
MFCD01656164
4-(N-Ethyl-N-(4-methoxy-alpha-methylphenethyl)amino)-1-butanol
N-Ethyl-N-(4-hydroxybutyl)-4-methoxy-alpha-methylphenethylamine
Phenethylamine, N-ethyl-N-(4-hydroxybutyl)-4-methoxy-alpha-methyl-
Mebeverine EP Impurity C
UNII-2UK92XY6H9
orb1709161
DTXSID60931982
EX-A4578
MebeverinemetaboliteMebeverinealcohol
1-BUTANOL, 4-(N-ETHYL-N-(4-METHOXY-alpha-METHYLPHENETHYL)AMINO)-
AKOS030239782
BS-15122
HY-12770
D83661
MEBEVERINE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
4-[ethyl-[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]butan-1-ol
1-BUTANOL, 4-(ETHYL(2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)-
4-(ETHYL((2RS)-1-(4-METHOXYPHENYL)PROPAN-2-YL)AMINO)BUTAN-1-OL