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Phenazone

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Identification
Molecular formula
C11H12N2O
CAS number
60-80-0
IUPAC name
4-(ethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one
State
State

Phenazone is a solid at room temperature. It is usually encountered in pharmaceutical environments as a stable compound used for medicinal purposes, particularly for its analgesic and anti-inflammatory properties.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
359.40
Boiling point (Kelvin)
632.50
General information
Molecular weight
188.23g/mol
Molar mass
188.2320g/mol
Density
1.0830g/cm3
Appearence

Phenazone is typically in the form of a white or almost white crystalline powder. It is odorless and has a slightly bitter taste. It may also appear as colorless crystals.

Comment on solubility

Solubility of 4-(ethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one

The solubility of 4-(ethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one can be influenced by several factors, making it an intriguing compound for study. Here are some key points to consider:

  • Polarity: The compound contains a hydrophilic ethylamino group which may enhance its interaction with water, suggesting moderate solubility in polar solvents.
  • Temperature Dependence: As with many organic compounds, its solubility may increase with temperature, making it more soluble in warm solvents compared to cold.
  • Solvent Effects: The solubility is also highly dependent on the solvent used. For instance, while it may dissolve in alcohols or dimethyl sulfoxide (DMSO), it might exhibit reduced solubility in non-polar solvents.
  • Chemical Structure: The presence of a phenyl group could contribute to pi-stacking interactions, potentially affecting solubility in various organic matrices.

In conclusion, the solubility of 4-(ethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one is characterized by a balance of its chemical structure and environmental conditions. Researchers should consider these factors when assessing its solubility in both laboratory and practical applications.

Interesting facts

Interesting Facts about 4-(Ethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one

4-(Ethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one, often referred to in scientific studies by its systematic name, is a fascinating compound that falls within the family of pyrazolones. This compound has garnered attention due to its unique structural characteristics and potential applications in various fields.

Key Characteristics

  • Structural Diversity: The presence of both ethylamine and phenyl groups in its structure contributes to its interesting chemical reactivity and biological activity.
  • Pharmaceutical Potential: Compounds in the pyrazolone class have been explored for their potential as anti-inflammatory and analgesic agents. Thus, this compound may exhibit similar properties.
  • Versatile Synthesis: The synthetic pathways for creating this compound typically involve efficient methodologies that are valuable in organic chemistry.

Applications

This compound might be especially relevant in the fields of medicinal chemistry and drug development. Research has indicated that derivatives of pyrazolones can interact with the central nervous system, suggesting opportunities for exploring:

  • Neurological therapeutic agents
  • A novel class of analgesics
  • Compounds with anti-tumor activity

Quote from Research

As one research study suggests, "The unique functional groups present in pyrazolone derivatives contribute to their biological diversity, opening avenues for novel therapeutic strategies."

In conclusion, 4-(ethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one is more than just a simple compound; it embodies the intersection of structural innovation and potential therapeutic efficacy, making it a subject of ongoing research and interest within the scientific community.

Synonyms
ANTIPYRINE, 4-(ETHYLAMINO)-
4-(Ethylamino)antipyrine
15166-10-6
BRN 0212712
DTXSID70164840
4-25-00-03563 (Beilstein Handbook Reference)
DTXCID8087331
TA 2
4-(ethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one
SCHEMBL8940421
AKOS009156078