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4-Ethynylphenol

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Identification
Molecular formula
C8H6O
CAS number
873-62-1
IUPAC name
4-ethynylphenol
State
State

At room temperature, 4-Ethynylphenol is a solid. It can be stored in tightly closed containers to avoid degradation.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
266.00
Boiling point (Kelvin)
539.15
General information
Molecular weight
118.13g/mol
Molar mass
118.1280g/mol
Density
1.1700g/cm3
Appearence

4-Ethynylphenol typically appears as a white to slightly off-white crystalline solid. It is known to be sensitive to air and light, which may cause it to yellow over time. Due to its phenolic nature, 4-Ethynylphenol may also have a characteristic phenolic odor.

Comment on solubility

Solubility of 4-ethynylphenol

4-ethynylphenol, with the chemical formula C8H8O, exhibits intriguing solubility characteristics that merit examination.


Water Solubility

This compound tends to have low solubility in water. This limited solubility can primarily be attributed to:

  • Hydrophobic nature: The ethynyl group contributes to its hydrophobicity, making it less favorable for interaction with polar water molecules.
  • Hydrogen bonding: Although 4-ethynylphenol contains a hydroxyl (-OH) group that can form hydrogen bonds, its overall structure leads to stronger hydrophobic interactions.

Solubility in Organic Solvents

Conversely, 4-ethynylphenol is generally soluble in many organic solvents, which include:

  • Alcohols (e.g., ethanol)
  • Aromatics (e.g., benzene)
  • Ethers and ketones

In summary, while 4-ethynylphenol is not very soluble in water due to its hydrophobic characteristics, it finds better solubility in a variety of organic solvents, showcasing the balance and complexity of its molecular interactions.

Interesting facts

Interesting Facts about 4-Ethynylphenol

4-Ethynylphenol is a fascinating organic compound that has garnered attention due to its unique properties and potential applications. Here are some noteworthy aspects of this compound:

  • Chemical Structure: The compound features a phenolic structure with an ethynyl group attached to the para position, which enhances its reactivity and allows it to participate in various chemical reactions.
  • Applications in Synthesis: 4-Ethynylphenol is used as a building block in synthetic chemistry, particularly in the development of advanced materials and pharmaceuticals. It plays a crucial role in the formation of polymers, dyes, and agrochemicals.
  • Antioxidant Properties: Research has indicated that 4-ethynylphenol exhibits antioxidant activities, making it a potential candidate for inclusion in cosmetic formulations aimed at combating oxidative stress.
  • Versatility in Organic Chemistry: This compound can undergo various reactions, including nucleophilic substitution and metal-catalyzed cross-coupling reactions, which further attest to its versatility as an intermediate in organic synthesis.
  • Research Potential: Ongoing studies are exploring new uses of 4-ethynylphenol in nanotechnology and pharmaceuticals, particularly for targeted drug delivery and as a potential therapeutic agent.

In summary, 4-ethynylphenol is a compound with rich chemical characteristics and promising applications in various fields of science. Its unique structure and properties make it a valuable subject of study for chemists and researchers alike.

Synonyms
4-ethynylphenol
4-ethynyl-phenol
2200-91-1
Phenol, 4-ethynyl-
4-Hydroxyphenylacetylene
p-ethynylphenol
MFCD00078287
SCHEMBL218284
SCHEMBL241981
SCHEMBL1230118
DTXSID60905921
AKOS006239520
NSC 114470
SY032040
CS-0266218
EN300-743881
H51017
101052-19-1