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4-Fluoro-3-iodobenzoic acid

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Identification
Molecular formula
C7H4FIO2
CAS number
825-94-3
IUPAC name
4-fluoro-3-iodo-benzoic acid
State
State

At room temperature, 4-Fluoro-3-iodobenzoic acid is in the solid state. It can be handled as a solid under normal laboratory conditions.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
338.60
Boiling point (Kelvin)
611.75
General information
Molecular weight
266.01g/mol
Molar mass
266.0170g/mol
Density
2.0840g/cm3
Appearence

4-Fluoro-3-iodobenzoic acid generally appears as a white to off-white solid powder. It is crystalline in form and may have a slight characteristic odor typical of benzoic acid derivatives. This compound is intended primarily for laboratory uses and research purposes.

Comment on solubility

Solubility of 4-fluoro-3-iodo-benzoic acid

4-fluoro-3-iodo-benzoic acid, with the chemical formula C7H4F I O2, exhibits notable solubility properties that can be outlined as follows:

  • Solvent Polarity: This compound tends to be more soluble in polar solvents due to the presence of the carboxylic acid functional group. It can readily dissolve in water and other alcohols.
  • Temperature Influence: Solubility often increases with temperature. Warming the solvent may enhance the dissolution process.
  • Hydrogen Bonding: The carboxylic acid group can form hydrogen bonds with water molecules, contributing to its solubility.
  • Substituent Effects: The presence of both the 4-fluoro and 3-iodo substituents impacts the steric and electronic characteristics, potentially altering solubility compared to simpler benzoic acids.

Overall, while 4-fluoro-3-iodo-benzoic acid exhibits good solubility in various solvents, particularly polar ones, the extent of its solubility can depend on external conditions and the specific interactions with the solvent molecules.

Interesting facts

Interesting Facts about 4-Fluoro-3-iodo-benzoic Acid

4-Fluoro-3-iodo-benzoic acid is a fascinating compound within the realm of organic chemistry, known for its unique functional groups and versatile applications. Here are some intriguing points about this compound:

  • Halogenated Aromatics: The presence of both fluorine and iodine atoms makes this compound a member of the halogenated aromatic compounds. Halogenation is important for modifying the chemical properties of organic molecules and enhancing their reactivity.
  • Pharmaceutical Relevance: This compound's derivatives are often explored in drug design. The incorporation of halogens can significantly influence biological activity, making them valuable candidates for pharmaceutical research.
  • Reaction Pathways: 4-Fluoro-3-iodo-benzoic acid can serve as an intriguing substrate for various chemical reactions, including nucleophilic substitutions and coupling reactions. This versatility enables the synthesis of more complex organic molecules.
  • Environmental Significance: Understanding how halogenated compounds behave in the environment is essential, as their persistence can impact ecological systems. Research on their degradation processes contributes to environmental chemistry studies.
  • Research Applications: The study of compounds like 4-fluoro-3-iodo-benzoic acid is crucial for developing materials with enhanced properties, such as improved thermal stability or specific electronic characteristics.

To sum up, 4-fluoro-3-iodo-benzoic acid is not just a simple organic compound; it serves as a gateway to various fields, including medicinal chemistry, materials science, and environmental studies. Its unique structure and reactivity continue to attract attention from chemists worldwide.

Synonyms
4-fluoro-3-iodobenzoic acid
403-18-9
DTXSID00274507
DTXCID50203483
964-507-7
4-fluoro-3-iodo-benzoic Acid
MFCD03788556
3-iodo-4-fluorobenzoic acid
Benzoic acid, 4-fluoro-3-iodo-
4-fluoro-3-iodobenzoicacid
SCHEMBL7756184
IKSOHJRYPQRTLQ-UHFFFAOYSA-N
BCP26635
AKOS015919932
CS-W014591
FF67385
PS-7330
SY101473
DB-010523
EN300-107765
Z1269207858