Interesting facts
Interesting Facts about 4-fluoro-N'-phenyl-benzohydrazide
4-fluoro-N'-phenyl-benzohydrazide is a fascinating compound that has garnered interest in various fields of research, particularly in medicinal chemistry. Here are some engaging insights into this intriguing compound:
- Potent Biological Activity: This compound exhibits significant biological properties, making it a candidate for further pharmacological studies. Its potential use includes exploring its role as a therapeutic agent against several diseases.
- Structure-Activity Relationship (SAR): The incorporation of the 4-fluoro group is essential. Fluorine substitutions often enhance the lipophilicity and metabolic stability of drug candidates, thus influencing their pharmacokinetics.
- Chemical Versatility: 4-fluoro-N'-phenyl-benzohydrazide can serve as a building block for the synthesis of more complex molecules, supporting advancements in drug discovery and development.
- Research Applications: This compound is frequently utilized in the synthesis of various derivatives that could lead to more potent agents in the fight against diseases such as cancer or bacterial infections.
- Hydrazone Chemistry: Being part of the hydrazide functional group, it may partake in important hydrazone formation reactions, which are vital in both organic synthesis and biochemical pathways.
- Impact of Fluorine: The presence of fluorine in organic compounds not only affects their reactivity and stability but also enhances their bioavailability, which is a critical factor in drug design.
In summary, 4-fluoro-N'-phenyl-benzohydrazide represents a compelling intersection of structure, functionality, and biological activity, making it a compound of interest for future explorations in various scientific avenues.
Synonyms
4-fluoro-N'-phenylbenzohydrazide
1496-02-2
BENZOIC ACID, p-FLUORO-, 2-PHENYLHYDRAZIDE
p-Fluorobenzoic acid 2-phenylhydrazide
BRN 0959317
SCHEMBL9829474
DTXSID80164351
PGKDUKIHKGXXIY-UHFFFAOYSA-N
AKOS003791963
4-Fluorobenzoic acid, 2-phenylhydrazide
4-Fluorobenzoic acid-N'-phenylhydrazide
Solubility of 4-fluoro-N'-phenyl-benzohydrazide
4-fluoro-N'-phenyl-benzohydrazide exhibits some intriguing properties when it comes to solubility.
Solvent Interaction
This compound demonstrates variable solubility depending on the solvent used. In general, it is:
Effect of Temperature
As a general rule, increasing the temperature can enhance the solubility of 4-fluoro-N'-phenyl-benzohydrazide in organic solvents. An increase in molecular kinetic energy often leads to increased solvation interactions.
Factors Influencing Solubility
Several factors can influence the solubility of this compound:
In summary, while 4-fluoro-N'-phenyl-benzohydrazide is not highly soluble in water, it demonstrates appreciable solubility in various organic solvents, making it versatile for different chemical applications.