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4-Fluoro-N-phenyl-benzohydrazonoyl chloride

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Identification
Molecular formula
C13H9ClFN3
CAS number
38444-78-9
IUPAC name
4-fluoro-N-phenyl-benzohydrazonoyl chloride
State
State

At room temperature, 4-Fluoro-N-phenyl-benzohydrazonoyl chloride is typically in a solid state. When kept under stable conditions, it maintains its form effectively. Its solid form is ideal for transportation and handling in various chemical processes.

Melting point (Celsius)
184.50
Melting point (Kelvin)
457.65
Boiling point (Celsius)
300.50
Boiling point (Kelvin)
573.65
General information
Molecular weight
278.70g/mol
Molar mass
278.6960g/mol
Density
1.2830g/cm3
Appearence

4-Fluoro-N-phenyl-benzohydrazonoyl chloride is a solid compound, typically found as a crystalline powder. It is an organofluorine compound featuring phenyl groups, which generally contribute to its stability and specific chemical behavior. The color and size of the crystals can vary based on the purity and specific handling conditions.

Comment on solubility

Solubility of 4-fluoro-N-phenyl-benzohydrazonoyl chloride

The solubility of 4-fluoro-N-phenyl-benzohydrazonoyl chloride can be described as follows:

  • Solvent Compatibility: This compound tends to be soluble in organic solvents such as chloroform and ether, which is often the case for halogenated organic compounds.
  • Water Solubility: It is generally considered to be insoluble in water due to its hydrophobic nature and the presence of chlorine in its structure, which reduces overall polarity.
  • Temperature Effects: Solubility can vary with temperature; typically, increased temperature can enhance the solubility of this compound in organic solvents.
  • Reaction with Water: Upon exposure to water, hydrolysis may occur, affecting the stability of the compound and potentially altering its solubility characteristics.

In summary, while 4-fluoro-N-phenyl-benzohydrazonoyl chloride exhibits good solubility in certain organic solvents, its limited solubility in water makes it less versatile in aqueous environments. Understanding these solubility dynamics is crucial for its applications in synthesis and chemical reactions.

Interesting facts

Interesting Facts about 4-fluoro-N-phenyl-benzohydrazonoyl chloride

4-fluoro-N-phenyl-benzohydrazonoyl chloride is an intriguing compound that plays a significant role in various fields, particularly in organic synthesis and medicinal chemistry. Here are some captivating facts about this compound:

  • Substituent Significance: The presence of the 4-fluoro group enhances the compound's reactivity, making it a valuable building block in the formation of more complex chemical entities.
  • Hydrazone Chemistry: As a hydrazonoyl derivative, it participates in unique reactivity patterns, allowing for the synthesis of other derivatives that could be biologically active or useful in materials science.
  • Applications in Medicine: Compounds containing hydrazone functionalities have been explored for their potential medicinal properties, including anti-tumor activities.
  • Functional Group Versatility: The functionality of the acyl chloride in this compound allows for easy transformations, facilitating the formation of amides or other derivatives through reactions with various nucleophiles.
  • Therapeutic Potential: While research is ongoing, derivatives of benzohydrazonoyl chlorides have shown promise in studies related to neurodegenerative diseases and other health conditions.
  • Synthetic Utility: Chemists value this compound for its ability to serve as an intermediate in multi-step syntheses, providing a pathway to create compounds with tailored properties.

The multifaceted nature of 4-fluoro-N-phenyl-benzohydrazonoyl chloride makes it a compound worth studying. As we delve deeper into the world of chemistry, uncovering hidden potentials in such compounds can lead to significant advancements in various scientific fields.

Synonyms
25939-02-0
4-fluoro-N-phenylbenzenecarbohydrazonoyl chloride
RefChem:292893
SCHEMBL9441607
DTXSID101233279