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4-Fluorobutan-1-ol

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Identification
Molecular formula
C4H9FO
CAS number
372-93-0
IUPAC name
4-fluorobutan-1-ol
State
State

At room temperature, 4-Fluorobutan-1-ol is in a liquid state.

Melting point (Celsius)
-13.00
Melting point (Kelvin)
260.15
Boiling point (Celsius)
132.00
Boiling point (Kelvin)
405.15
General information
Molecular weight
92.10g/mol
Molar mass
92.1040g/mol
Density
1.1690g/cm3
Appearence

4-Fluorobutan-1-ol appears as a clear liquid. It is typically colorless and shows fluid properties similar to other simple alcohols.

Comment on solubility

Solubility of 4-fluorobutan-1-ol

4-fluorobutan-1-ol, with the chemical formula C4H9FO, exhibits notable solubility characteristics due to its molecular structure. The presence of the hydroxyl (-OH) group is a significant factor influencing its solubility:

  • Polar Nature: The hydroxyl group is highly polar, which aids in hydrogen bonding with water molecules, enhancing solubility in polar solvents.
  • Alkyl Chain: The butyl portion of the molecule, being hydrophobic, can limit solubility in water, yet the overall balance allows for reasonable solubility.
  • Comparative Solubility: In comparison to its non-fluorinated counterparts, the presence of the fluorine atom can influence the solubility, making it more compatible with organic solvents.

In practice, 4-fluorobutan-1-ol is soluble in:

  1. Water: Moderate solubility due to hydrogen bonding.
  2. Alcohols: Easily dissolvable in other alcohols owing to similar functional groups.
  3. Organic solvents: Soluble in various non-polar and polar organic solvents.

In summary, while 4-fluorobutan-1-ol has a level of solubility in water, its solubility profile is enhanced in organic environments. As with many compounds, the interplay between polarity and molecular structure dictates its solubility behavior, making it an interesting subject of study.

Interesting facts

Interesting Facts about 4-Fluorobutan-1-ol

4-Fluorobutan-1-ol is a fascinating chemical compound that falls under the category of alcohols, characterized by the presence of a hydroxyl group (-OH) in its structure. Here are some intriguing aspects of 4-fluorobutan-1-ol:

  • Fluorinated Alcohol: The addition of a fluorine atom in the butanol structure significantly alters its chemical properties compared to non-fluorinated alcohols. This makes it a unique candidate for various chemical reactions.
  • Synthetic Applications: The compound serves as a valuable building block in organic synthesis. It is often used in the development of pharmaceuticals and agrochemicals.
  • Biological Activity: Research has shown that fluorinated alcohols can exhibit various biological activities, making compounds like 4-fluorobutan-1-ol of interest in medicinal chemistry and drug design.
  • Solvate Effect: The introduction of fluorine can enhance the polarity of the alcohol, allowing for interesting solvate effects in solutions, which can be critical in biochemical processes.
  • Environmental Impact: As with many fluorinated compounds, there are ongoing studies to understand their environmental behavior and potential persistence in ecosystems, making their safe handling and disposal vital.

Overall, 4-fluorobutan-1-ol exemplifies how small changes in a chemical structure can lead to significant shifts in functionality and utility, highlighting the importance of molecular design in chemistry.

Synonyms
4-FLUORO-1-BUTANOL
372-93-0
4-fluorobutan-1-ol
4-Fluorobutanol
1-BUTANOL, 4-FLUORO-
61599-24-4
4-Fluoro-butan-1-ol
MFCD00039555
omega-Fluorobutanol
BRN 1697078
C4H9FO
CHEMBL4450925
DTXSID60190698
AKOS006274816
FF23366
DB-295296
E85260
EN300-206962
836-238-4