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4-Fluorobutane-1-sulfonyl fluoride

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Identification
Molecular formula
C4H8FO2S
CAS number
7360-38-5
IUPAC name
4-fluorobutane-1-sulfonyl fluoride
State
State

At room temperature, 4-Fluorobutane-1-sulfonyl fluoride is in a liquid state.

Melting point (Celsius)
-34.00
Melting point (Kelvin)
239.15
Boiling point (Celsius)
159.00
Boiling point (Kelvin)
432.15
General information
Molecular weight
162.17g/mol
Molar mass
162.1590g/mol
Density
1.2910g/cm3
Appearence

4-Fluorobutane-1-sulfonyl fluoride is typically a clear, colorless liquid.

Comment on solubility

Solubility of 4-fluorobutane-1-sulfonyl fluoride

The solubility of 4-fluorobutane-1-sulfonyl fluoride is influenced by several factors, making it a compound of interest in various chemical applications. This compound, known for its unique structure, exhibits the following characteristics regarding its solubility:

  • Polar Nature: Due to the presence of the sulfonyl fluoride group, the compound is polar, which often enhances its solubility in polar solvents.
  • Solvent Interaction: It tends to dissolve well in solvents such as water and alcohols, which can stabilize its polar nature.
  • Temperature Dependence: Like many chemical compounds, its solubility can increase with temperature, allowing for more effective use in reactions at higher temperatures.
  • Limited Solubility in Nonpolar Solvents: Conversely, 4-fluorobutane-1-sulfonyl fluoride is likely to have low solubility in nonpolar solvents due to its polar characteristics, limiting its use in such environments.

In summary, understanding the solubility of 4-fluorobutane-1-sulfonyl fluoride is crucial for its application in organic synthesis, where the choice of solvent can greatly affect the overall reaction efficiency and outcome. By focusing on its polar nature and favorable interactions with polar solvents, chemists can optimize its use in the laboratory.

Interesting facts

Interesting Facts about 4-Fluorobutane-1-sulfonyl Fluoride

4-Fluorobutane-1-sulfonyl fluoride is a fascinating chemical compound, particularly known for its applications in organic synthesis and biochemistry. Here are some noteworthy aspects of this compound:

  • Versatile Reagent: This compound functions as an important sulfonylating reagent, enabling the introduction of sulfonyl groups into various organic molecules. It is widely used in reaction mechanisms to form sulfonamide bonds.
  • Fluorine's Influence: The presence of the fluorine atom in 4-fluorobutane-1-sulfonyl fluoride significantly affects the reactivity and stability of the compound, allowing it to participate in unique reactions that are otherwise difficult to achieve.
  • Structural Significance: This compound is part of the broader class of sulfonyl fluorides, which are known for their ability to activate nucleophiles. Its structure provides insight into the interaction of sulfur compounds in synthetic pathways.

Furthermore, 4-fluorobutane-1-sulfonyl fluoride is considered a valuable tool in pharmaceutical chemistry. Scientists often cite its utility in designing intermediates for complex molecules. As a testimony to its significance, researchers have remarked:

"The ability of sulfonyl fluorides to selectively modify functional groups has opened new avenues in the field of medicinal chemistry."

Its applications continue to expand as chemists explore its role in the development of novel therapeutics and materials. The realm of sulfonyl fluorides presents boundless possibilities for innovative discoveries in chemical science.

Synonyms
4-Fluorobutanesulphonyl fluoride
660-14-0
BUTANESULFONYL FLUORIDE, 4-FLUORO-
BRN 1759301
DTXSID80216208
4-04-00-00047 (Beilstein Handbook Reference)
DTXCID40138699
4-fluorobutane-1-sulfonyl fluoride
SCHEMBL19421383
EN300-727778