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4-Fluorobutyronitrile

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Identification
Molecular formula
C4H6FN
CAS number
1975-55-3
IUPAC name
4-fluorobutanenitrile
State
State

At room temperature, 4-fluorobutyronitrile is a liquid.

Melting point (Celsius)
-62.00
Melting point (Kelvin)
211.15
Boiling point (Celsius)
122.00
Boiling point (Kelvin)
395.15
General information
Molecular weight
89.10g/mol
Molar mass
89.1010g/mol
Density
1.0076g/cm3
Appearence

4-Fluorobutyronitrile is a colorless liquid. Its appearance is devoid of any significant color, typical of many small nitrile compounds.

Comment on solubility

Solubility of 4-fluorobutanenitrile

4-fluorobutanenitrile, with the molecular formula C4H6FN, exhibits notable solubility characteristics that are important to consider in both industrial and laboratory settings. The presence of the nitrile group (-C≡N) enhances its polarity, resulting in increased solubility in polar solvents. Here are some key points regarding its solubility:

  • Polar Solvents: 4-fluorobutanenitrile is highly soluble in polar solvents such as water, ethanol, and methanol due to its ability to form hydrogen bonds.
  • Hydrophobic Character: Its chain length and fluorine substitution introduce a degree of hydrophobicity, which may reduce solubility in non-polar solvents.
  • Temperature Dependence: The solubility can increase with temperature, making it more effective in applications that require higher energy states.

In summary, when considering the application of 4-fluorobutanenitrile, it is crucial to recognize that its solubility is significantly influenced by both its functional groups and the solvent interactions. Understanding these aspects can optimize its usage across various chemical processes.

Interesting facts

Interesting Facts about 4-Fluorobutanenitrile

4-Fluorobutanenitrile, often abbreviated as 4-FBN, is a fascinating compound that blends both the characteristics of organic chemistry and practical applications. Here are some intriguing insights into this compound:

  • Structure and Functionality: 4-Fluorobutanenitrile is a nitrile, which means it contains a cyano group (–C≡N). This functional group is integral to many chemical reactions, making 4-FBN a valuable intermediate in synthetic organic chemistry.

  • Fluorine Focus: The presence of the fluorine atom enhances the reactivity of the compound. Fluorine is known for its electronegativity, and the substitution in 4-Fluorobutanenitrile can influence its chemical behavior in various reactions.

  • Applications: This compound is utilized in the pharmaceutical industry, particularly in the synthesis of fluorinated pharmaceuticals, which often exhibit enhanced biological activity.

  • Biological Significance: Research has suggested that compounds featuring a fluoro group can demonstrate unique interactions with biological targets, making 4-Fluorobutanenitrile a subject of interest for drug design and discovery.

  • Environmental Considerations: With the increasing focus on sustainable chemistry, nitriles like 4-Fluorobutanenitrile are being studied for their potential biodegradability and environmental impact.

As a science enthusiast or chemist, exploring compounds like 4-fluorobutanenitrile opens up a world of possibilities in understanding reactivity and functionality in synthetic chemistry. The interplay of fluorine's unique properties with the nitrile group showcases the complexity and beauty of chemical compounds.

Synonyms
4-fluorobutanenitrile
407-83-0
4-Fluorobutyronitrile
BUTYRONITRILE, 4-FLUORO-
gamma-Fluorobutyronitrile
TL 1126
BRN 1739312
DTXSID20193680
4-02-00-00809 (Beilstein Handbook Reference)
DTXCID60116171
AKOS019676441
EN300-244229
G53346