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Thiazole-5-carboximidamide

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Identification
Molecular formula
C6H7N5S
CAS number
1078-21-3
IUPAC name
4-formamido-1H-imidazole-5-carboximidothioic acid
State
State
This compound is typically a solid at room temperature. Its crystalline form is stable under standard laboratory conditions, maintaining its powdered consistency.
Melting point (Celsius)
227.00
Melting point (Kelvin)
500.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
141.19g/mol
Molar mass
141.1880g/mol
Density
1.3300g/cm3
Appearence

Thiazole-5-carboximidamide appears as a yellow powder, which may vary in shade depending on its purity and specific synthesis method. This compound is typically crystalline and has a distinct texture indicative of its molecular structure.

Comment on solubility

Solubility of 4-formamido-1H-imidazole-5-carboximidothioic acid

The solubility of 4-formamido-1H-imidazole-5-carboximidothioic acid can be assessed through various factors that influence its behavior in different solvents. Its unique molecular structure suggests that it may exhibit:

  • Moderate solubility in polar solvents: Given the presence of both carboxylic and amine functional groups, this compound is likely soluble in water and other polar solvents due to hydrogen bonding.
  • Limited solubility in non-polar solvents: The presence of sulfur and nitrogen, characteristic of its thioic acid group, may hinder solubility in non-polar environments.
  • Potential pH dependence: The solubility might vary with changing pH levels, particularly due to the ionizable groups, suggesting that the compound's dissociation could lead to increased solubility in basic conditions.

In conclusion, while a precise solubility parameter may be difficult to establish without experimental data, it is reasonable to presume that 4-formamido-1H-imidazole-5-carboximidothioic acid displays greater solubility in aqueous solutions compared to organic solvents. Further studies would undoubtedly refine our understanding of its solubility characteristics.

Interesting facts

Interesting Facts about 4-formamido-1H-imidazole-5-carboximidothioic acid

4-formamido-1H-imidazole-5-carboximidothioic acid is a fascinating compound that has garnered attention in various fields of scientific research. Below are some intriguing aspects of this compound:

  • Biological Significance: This compound contains an imidazole ring, which is a key structural feature found in many biologically active molecules, including amino acids such as histidine. The presence of the formamido group enhances its potential as a bioactive agent.
  • Potential Applications: 4-formamido-1H-imidazole-5-carboximidothioic acid may have applications in medicinal chemistry due to its unique structural composition. Researchers are exploring its role in the development of new drugs, particularly in targeting specific enzymes and receptors.
  • Synthesis Pathways: The synthesis of this compound involves various organic reactions, making it an excellent example of organic synthesis in practice. Its straightforward synthesis can serve as a curriculum point for chemistry students interested in organic methodologies.
  • Research Role: This compound is often studied in relation to its interactions with biological systems, providing insights into the mechanisms of drug action and the design of new therapeutic strategies.
  • Environmental Considerations: As scientists become more aware of the environmental impact of chemical substances, studying the degradation and stability of compounds like 4-formamido-1H-imidazole-5-carboximidothioic acid is becoming increasingly vital.

In conclusion, 4-formamido-1H-imidazole-5-carboximidothioic acid stands as an excellent intersection of synthetic chemistry and biological research. As researchers continue to uncover its properties and potential applications, it will undoubtedly play a role in advancing both fundamental chemistry and applied sciences.