HOBt (Hydroxybenzotriazole) | Solubility of Things

Identification

Molecular formula

C₆H₅N₃O

CAS number

2592-95-2

IUPAC name

4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine

State

At room temperature, hydroxybenzotriazole is a solid.

Melting point (Celsius)

156.00

Melting point (Kelvin)

429.15

Boiling point (Celsius)

290.00

Boiling point (Kelvin)

563.15

General information

Molecular weight

135.13g/mol

Molar mass

135.1260g/mol

Density

1.5000g/cm³

Appearence

Hydroxybenzotriazole usually appears as a white to pale beige crystalline powder. The appearance can sometimes be slightly off-white depending on the sample purity and any exposure to humidity.

Comment on solubility

Solubility of 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine

The solubility of 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine presents interesting characteristics influenced by its unique structure. This compound contains functional groups that may interact favorably with solvents, particularly polar solvents.

Factors Influencing Solubility:

Polarity: The presence of hydroxyl (-OH) and imine (=N-) groups indicates that the compound can engage in hydrogen bonding, enhancing its solubility in polar solvents like water.
Hydrogen Bonding: The ability to form hydrogen bonds can significantly improve solubility. It is essential to consider how the compound interacts on a molecular level with surrounding solvent molecules.
pH Dependence: The compound may display variable solubility depending on the pH of the medium, as ionization of the nitrogen-containing functional groups can change with different pH levels.

In summary, while specific empirical data on solubility may vary, it is generally expected that 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine exhibits good solubility in polar solvents due to the compound's structure and favorable interactions with such solvents. Understanding these solubility properties is crucial for applications in various chemical processes and formulations.

Interesting facts

Interesting Facts about 4-Hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine

This intriguing compound belongs to the class of benzotriazines, which are known for their diverse applications in various fields, including pharmaceuticals and materials science. Here are some key points that highlight the significance and uniqueness of this compound:

Structural Diversity: The presence of both hydroxy and oxido functional groups in its structure enhances its chemical reactivity. This structural diversity allows for interesting intermolecular interactions that can affect its behavior in different environments.
Biological Potential: Compounds in the benzotriazine family have garnered attention for their potential biological activity. They are often studied for their ability to act as antioxidants or even as anti-cancer agents, making their research critical in medicinal chemistry.
Stability and Reactivity: The unique combination of imine and oxido functionalities contributes to its stability while also providing opportunities for further chemical reactions, allowing for convenient synthetic pathways in laboratory settings.
Functionality in Safety: Some derivatives of this compound can serve as photostabilizers in polymers, helping to enhance the durability and longevity of materials exposed to sunlight, thus making them invaluable in various industrial applications.

In summary, the compound 4-hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine is not just a simple chemical entity; its multifaceted nature makes it a subject of ongoing research and exploration in both academic and industrial chemistry. As we continue to discover more about its properties and potential applications, this compound may pave the way for innovative solutions to current challenges.