Skip to main content

Genistein

ADVERTISEMENT
Identification
Molecular formula
C15H10O5
CAS number
446-72-0
IUPAC name
4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one
State
State

At room temperature, genistein is a crystalline solid.

Melting point (Celsius)
297.00
Melting point (Kelvin)
570.15
Boiling point (Celsius)
678.30
Boiling point (Kelvin)
951.50
General information
Molecular weight
270.24g/mol
Molar mass
270.2410g/mol
Density
1.4138g/cm3
Appearence

Genistein typically appears as a yellow crystalline solid, sometimes with a slight brown hue. It is insoluble in water but soluble in organic solvents like DMSO and ethanol.

Comment on solubility

Solubility of 4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one

The solubility of 4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one is a topic of significant interest in the field of chemistry, especially for applications in pharmaceuticals and formulations.

Key points regarding its solubility:

  • Solvent Interactions: This compound displays varying solubility depending on the solvent used. Generally, it is more soluble in polar solvents due to the presence of hydroxyl (–OH) groups that can form hydrogen bonds.
  • pH Sensitivity: The solubility can be influenced by pH levels; increasing the pH may lead to an increase in solubility, as deprotonation of the –OH groups occurs.
  • Temperature Dependence: Solubility is also temperature-dependent. As temperature rises, an increase in kinetic energy may enhance the solubility of the compound in various solvents.
  • Crystalline vs. Amorphous Forms: The crystalline form is often less soluble than its amorphous counterpart due to differences in molecular packing and interaction with solvents.

In summary, the solubility of 4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one can be described as polar solvent-friendly, temperature-sensitive, and pH-dependent. Understanding these aspects is essential for its practical applications in diverse chemical environments.

Interesting facts

Interesting Facts about 4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one

4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one is a fascinating compound that belongs to the class of flavonoids, a group renowned for their diverse biological activities. This specific flavonoid is chemically significant due to its unique structure, which contributes to its various properties:

  • Natural Source: This compound can be derived from natural sources, particularly in plants, where it plays a vital role in the plant's defense mechanisms against environmental stressors.
  • Antioxidant Activity: Flavonoids are well-known for their antioxidant properties. Studies have shown that 4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one exhibits notable antioxidant effects, which help to neutralize harmful free radicals in the body.
  • Health Benefits: This compound is being researched for its potential health benefits, including anti-inflammatory, anti-cancer, and cardiovascular protective effects.
  • Biological Research: The compound’s structure allows it to interact with various biological pathways, making it a subject of investigation in pharmacological studies.
  • Colorant and Flavoring: Like many flavonoids, it may also be used in the food industry for its coloring properties, enhancing the visual appeal of food products.

Moreover, its ability to modulate enzymatic activity and cell signaling pathways makes it an interesting topic for chemists and biologists alike. As the renowned scientist Dr. Albert Szent-Györgyi once said, "Discovery consists of seeing what everybody has seen and thinking what nobody has thought." The study of 4-hydroxy-2-(4-hydroxyphenyl)chromen-7-one invites us to delve deeper into its potential, paving the way for exciting advancements in the fields of medicine and nutrition.