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4-Hydroxy-3-nitrobenzaldehyde

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Identification
Molecular formula
C7H5NO4
CAS number
619-21-6
IUPAC name
4-hydroxy-3-nitro-benzaldehyde
State
State
At room temperature, 4-Hydroxy-3-nitrobenzaldehyde is a solid. It is stable and usually handled easily without any reactive hazards under ambient conditions. The compound should be handled carefully to prevent inhalation or ingestion.
Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
309.00
Boiling point (Kelvin)
582.15
General information
Molecular weight
181.12g/mol
Molar mass
181.1340g/mol
Density
1.4670g/cm3
Appearence

4-Hydroxy-3-nitrobenzaldehyde appears as a yellow crystalline solid. The compound may also exhibit a powdery texture, typical for many nitroaromatic compounds. It is generally stable under normal conditions but should be stored in a cool, dry place to prevent any potential degradation.

Comment on solubility

Solubility of 4-hydroxy-3-nitro-benzaldehyde

4-hydroxy-3-nitro-benzaldehyde, also known as m-nitrohydroxybenzaldehyde, presents interesting solubility characteristics that are important for its applications in organic synthesis and various chemical reactions. Here are some key points regarding its solubility:

  • Polar and Non-Polar Solvent Interaction: This compound is somewhat polar due to the presence of both the hydroxyl group and nitro group, which influences its solubility in different solvents.
  • Solubility in Water: Generally, 4-hydroxy-3-nitro-benzaldehyde is sparingly soluble in water. The presence of the hydroxyl group does enhance its ability to interact with water molecules, albeit to a limited extent.
  • Solubility in Organic Solvents: It demonstrates improved solubility in organic solvents such as ethanol, methanol, and acetone. This property is indicative of its capacity to interact better with non-polar or slightly polar solvents.
  • Influence of pH: The solubility may also vary with changes in pH, particularly due to the ionization of the hydroxyl and nitro groups in different acidic or basic environments.

In conclusion, while 4-hydroxy-3-nitro-benzaldehyde is not highly soluble in water, its solubility in organic solvents enhances its utility in chemical synthesis. As noted, the balance of polar and non-polar characteristics is pivotal in determining its solubility profile. Hence, exploring its solubility in various conditions is essential for effective application in synthetic chemistry.

Interesting facts

Interesting Facts about 4-Hydroxy-3-nitro-benzaldehyde

4-Hydroxy-3-nitro-benzaldehyde, also known as a versatile organic compound, plays a significant role in various chemical applications. Here are some captivating facts about this compound:

  • Functional Groups: This compound features both a hydroxyl group and a nitro group, which make it an important intermediate in organic synthesis.
  • Synthetic Applications: It is commonly used in the synthesis of pharmaceuticals and agrochemicals, highlighting its importance in the chemical industry.
  • Analytical Chemistry: The presence of both functional groups allows for its application in various analytical techniques, including UV-Vis spectroscopy.
  • Biological Activity: Research shows that derivatives of this compound exhibit antimicrobial and anti-inflammatory activities, indicating potential therapeutic uses.
  • Colorimetric Reactions: Due to its reactivity, 4-hydroxy-3-nitro-benzaldehyde is also employed in colorimetric reactions, providing visual indicators in laboratory settings.

As a noteworthy compound in chemistry, 4-hydroxy-3-nitro-benzaldehyde exemplifies how complex molecules can serve various functions in both research and industry. Its ability to act as an important precursor showcases the interconnectedness of organic compounds in developing new technologies and pharmaceuticals.

In summary, 4-hydroxy-3-nitro-benzaldehyde is more than just a compound; it is a gateway to innovation and discovery in the field of chemistry!

Synonyms
4-Hydroxy-3-nitrobenzaldehyde
3011-34-5
Benzaldehyde, 4-hydroxy-3-nitro-
EINECS 221-141-6
NSC 138267
DTXSID80184195
DTXCID90106686
221-141-6
inchi=1/c7h5no4/c9-4-5-1-2-7(10)6(3-5)8(11)12/h1-4,10
ythjczrfjgxptl-uhfffaoysa-n
4-FORMYL-2-NITROPHENOL
MFCD00007117
4-hydroxy-3-nitro-benzaldehyde
CHEMBL378361
3-nitro-4-hydroxybenzaldehyde
4-Hydroxy-3-nitrobenzaldehyde; NSC 138267; 3-Nitro-4-hydroxybenzaldehyde
NSC138267
SCHEMBL244093
4-hydroxyl-3-nitrobenzaldehyde
4-Hydroxy-3-nitro benzaldehyde
BBL023246
BDBM50177410
STK397481
4-Hydroxy-3-nitrobenzaldehyde, 97%
AKOS000120628
AC-2992
CS-W019280
FH32308
NSC-138267
PS-6187
BP-14084
PD182199
SY003511
DB-014481
H0924
NS00028860
EN300-18187
O11241
Z57313904
F0001-3459